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LOC112163605 Sharpr-MPRA regulatory region 2055 [ Homo sapiens (human) ]

Gene ID: 112163605, updated on 7-Jul-2021


Gene symbol
Gene description
Sharpr-MPRA regulatory region 2055
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
This genomic sequence was predicted to be a transcriptional regulatory region based on chromatin state analysis from the ENCODE (ENCyclopedia Of DNA Elements) project. It was validated as a functional enhancer by the Sharpr-MPRA technique (Systematic high-resolution activation and repression profiling with reporter tiling using massively parallel reporter assays) in K562 erythroleukemia cells (group: K562 Activating DNase unmatched - State 13:Ctcf, distal CTCF/candidate insulator without open chromatin), with weaker activity in HepG2 liver carcinoma cells (group: HepG2 Activating DNase matched - State 1:Tss, active promoter, TSS/CpG island region). [provided by RefSeq, Jul 2021]
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Genomic context

See LOC112163605 in Genome Data Viewer
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 12 NC_000012.12 (52024785..52025079)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (52418569..52418863)

Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene activin A receptor type 1B Neighboring gene RNA, U6 small nuclear 574, pseudogene Neighboring gene TAMALIN antisense RNA 1 Neighboring gene trafficking regulator and scaffold protein tamalin Neighboring gene nuclear receptor subfamily 4 group A member 1 Neighboring gene uncharacterized LOC107984510 Neighboring gene NR4A1 antisense RNA

Genomic regions, transcripts, and products

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.


  1. NG_056586.1 

    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly


  1. NC_000012.12 Reference GRCh38.p13 Primary Assembly

    GenBank, FASTA, Sequence Viewer (Graphics)
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