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Snurf SNRPN upstream open reading frame [ Rattus norvegicus (Norway rat) ]

Gene ID: 113938, updated on 13-Apr-2024

Summary

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Official Symbol
Snurfprovided by RGD
Official Full Name
SNRPN upstream open reading frameprovided by RGD
Primary source
RGD:69269
See related
AllianceGenome:RGD:69269
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable ATPase binding activity. Predicted to be located in nucleoplasm. Predicted to be active in nuclear speck. Orthologous to human SNURF (SNRPN upstream open reading frame). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Brain (RPKM 1941.8), Heart (RPKM 609.9) and 2 other tissues See more
Orthologs
human mouse all
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Genomic context

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Location:
1q22
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (120316846..120339153, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (111101327..111123634, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (195074328..195096694, complement)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA, C/D box 64 Neighboring gene small nucleolar RNA, C/D box 107 Neighboring gene ras homolog family member G, pseudogene 3 Neighboring gene small nuclear ribonucleoprotein polypeptide N Neighboring gene uncharacterized LOC134483395 Neighboring gene COMM domain containing 9, pseudogene 1 Neighboring gene solute carrier family 25 member 19 like 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Small nuclear RING finger protein stimulates the rat luteinizing hormone-beta promoter by interacting with Sp1 and steroidogenic factor-1 and protects from androgen suppression. Curtin D, et al. Mol Endocrinol, 2004 May. PMID 14988433
  2. An imprinted, mammalian bicistronic transcript encodes two independent proteins. Gray TA, et al. Proc Natl Acad Sci U S A, 1999 May 11. PMID 10318933, Free PMC Article
  3. Novel ATPase of SNF2-like protein family interacts with androgen receptor and modulates androgen-dependent transcription. Rouleau N, et al. Mol Biol Cell, 2002 Jun. PMID 12058073, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables ATPase binding ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
is_active_in nuclear speck IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nuclear speck ISO
Inferred from Sequence Orthology
more info
  
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in nucleus ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
SNRPN upstream reading frame protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001270712.1 → NP_001257641.1  SNRPN upstream reading frame protein

    See identical proteins and their annotated locations for NP_001257641.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Both variants encode the same protein.
    Source sequence(s)
    BC098906, JAXUCZ010000001
    UniProtKB/Swiss-Prot
    Q9WU11
    Conserved Domains (1) summary
    pfam07192
    Location:4 → 68
    SNURF; SNURF/RPN4 protein

  2. NM_130738.2 → NP_570094.1  SNRPN upstream reading frame protein

    See identical proteins and their annotated locations for NP_570094.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 3' UTR compared to variant 1. Both variants encode the same protein.
    Source sequence(s)
    BC081739, JAXUCZ010000001
    UniProtKB/Swiss-Prot
    Q9WU11
    Conserved Domains (1) summary
    pfam07192
    Location:4 → 68
    SNURF; SNURF/RPN4 protein

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    120316846..120339153 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9WU11.1 GenPept UniProtKB/Swiss-Prot:Q9WU11

Gene LinkOut

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