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ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 [ Rhinatrema bivittatum (two-lined caecilian) ]

Gene ID: 115084587, updated on 17-Mar-2024

Summary

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Gene symbol
ARAP2
Gene description
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
Gene type
protein coding
RefSeq status
MODEL
Organism
Rhinatrema bivittatum
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Gymnophiona; Rhinatrematidae; Rhinatrema
Orthologs
human mouse all
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Genomic context

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See ARAP2 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
35
Annotation release Status Assembly Chr Location
100 current aRhiBiv1.1 (GCF_901001135.1) 1 NC_042615.1 (165680281..166300223)

Chromosome 1 - NC_042615.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC115084571 Neighboring gene death domain containing 1 Neighboring gene myb-related transcription factor, partner of profilin-like Neighboring gene uncharacterized LOC115080209

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_042615.1 Chromosome 1 Reference aRhiBiv1.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Multi-tissue transcriptomes of caecilian amphibians highlight incomplete knowledge of vertebrate gene families. Torres-Sánchez M, et al. DNA Res, 2019 Feb 1. PMID 30351380, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphatidylinositol-3,4,5-trisphosphate binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Rhinatrema bivittatum Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference aRhiBiv1.1 Primary Assembly

Genomic

  1. NC_042615.1 Reference aRhiBiv1.1 Primary Assembly

    Range
    165680281..166300223
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_029589653.1 → XP_029445513.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 isoform X1

    Conserved Domains (6) summary
    cd04385
    Location:1122 → 1300
    RhoGAP_ARAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in ARAPs. ARAPs (also known as centaurin deltas) contain, besides the RhoGAP domain, an Arf GAP, ankyrin repeat ras-associating, and PH domains. Since their ArfGAP activity ...
    cd13253
    Location:494 → 587
    PH1_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 1
    cd08856
    Location:688 → 808
    ArfGap_ARAP2; ArfGap with Rho-Gap domain, ANK repeat and PH domain-containing protein 2
    cl15755
    Location:11 → 68
    SAM_superfamily; SAM (Sterile alpha motif )
    cl17171
    Location:899 → 1009
    PH-like; Pleckstrin homology-like domain
    cl28922
    Location:1332 → 1428
    Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold

  2. XM_029589667.1 → XP_029445527.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 isoform X2

  3. XM_029589686.1 → XP_029445546.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 isoform X4

  4. XM_029589677.1 → XP_029445537.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 isoform X3

  5. XM_029589662.1 → XP_029445522.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 isoform X1

    Conserved Domains (6) summary
    cd04385
    Location:1122 → 1300
    RhoGAP_ARAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in ARAPs. ARAPs (also known as centaurin deltas) contain, besides the RhoGAP domain, an Arf GAP, ankyrin repeat ras-associating, and PH domains. Since their ArfGAP activity ...
    cd13253
    Location:494 → 587
    PH1_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 1
    cd08856
    Location:688 → 808
    ArfGap_ARAP2; ArfGap with Rho-Gap domain, ANK repeat and PH domain-containing protein 2
    cl15755
    Location:11 → 68
    SAM_superfamily; SAM (Sterile alpha motif )
    cl17171
    Location:899 → 1009
    PH-like; Pleckstrin homology-like domain
    cl28922
    Location:1332 → 1428
    Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold
Nucleotide Protein
Heading Accession and Version

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