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Adh1 alcohol dehydrogenase 1 (class I) [ Mus musculus (house mouse) ]

Gene ID: 11522, updated on 5-Sep-2021

Summary

Official Symbol
Adh1provided by MGI
Official Full Name
alcohol dehydrogenase 1 (class I)provided by MGI
Primary source
MGI:MGI:87921
See related
Ensembl:ENSMUSG00000074207
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
ADH; Adh-; Adh-1; Adh1-; ADH-A2; ADH-AA; Adh-1-; Adh-1e; Adh-1t; Adh-3e; Adh1-e; Adh1-t; Adh1tl; Adh3-e; Adh-1-t; AI194826
Expression
Biased expression in liver adult (RPKM 1139.9), adrenal adult (RPKM 886.1) and 9 other tissues See more
Orthologs
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Genomic context

See Adh1 in Genome Data Viewer
Location:
3 G3; 3 64.16 cM
Exon count:
9
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (137983346..137996459)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (138277585..138290698)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 3 NC_000069.5 (137940609..137953655)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 0610031O16 gene Neighboring gene alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide Neighboring gene predicted gene, 40156 Neighboring gene Adh1 promoter region Neighboring gene predicted gene 16559 Neighboring gene alcohol dehydrogenase 6A (class V)

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables NAD binding ISO
Inferred from Sequence Orthology
more info
 
enables NAD-retinol dehydrogenase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables NAD-retinol dehydrogenase activity ISO
Inferred from Sequence Orthology
more info
 
enables alcohol dehydrogenase (NAD+) activity IDA
Inferred from Direct Assay
more info
PubMed 
enables alcohol dehydrogenase (NAD+) activity ISO
Inferred from Sequence Orthology
more info
 
enables alcohol dehydrogenase (NAD+) activity TAS
Traceable Author Statement
more info
PubMed 
enables alcohol dehydrogenase activity, zinc-dependent IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables alcohol dehydrogenase activity, zinc-dependent ISO
Inferred from Sequence Orthology
more info
 
enables ethanol binding ISO
Inferred from Sequence Orthology
more info
 
enables identical protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables organic cyclic compound binding ISO
Inferred from Sequence Orthology
more info
 
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 
enables zinc ion binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables zinc ion binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in acetaldehyde biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within behavioral response to ethanol IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within ethanol catabolic process IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within ethanol catabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in ethanol oxidation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in ethanol oxidation ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within response to retinoic acid IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within response to steroid hormone IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within response to testosterone IDA
Inferred from Direct Assay
more info
PubMed 
involved_in retinoic acid metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within retinoic acid metabolic process IGI
Inferred from Genetic Interaction
more info
PubMed 
acts_upstream_of_or_within retinoic acid metabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within retinoid metabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in retinol metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within retinol metabolic process IGI
Inferred from Genetic Interaction
more info
PubMed 
acts_upstream_of_or_within retinol metabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in intracellular anatomical structure IDA
Inferred from Direct Assay
more info
PubMed 
located_in mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
alcohol dehydrogenase 1
Names
alcohol dehydrogenase 1 temporal, liver
alcohol dehydrogenase 1, complex
alcohol dehydrogenase 1, electrophoretic
alcohol dehydrogenase 3, electrophoretic
alcohol dehydrogenase A subunit
class I alcohol dehydrogenase
NP_031435.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_007409.3NP_031435.1  alcohol dehydrogenase 1

    See identical proteins and their annotated locations for NP_031435.1

    Status: VALIDATED

    Source sequence(s)
    AC079682, AI256543, AI326887, CD355981, DV044803
    Consensus CDS
    CCDS17867.1
    UniProtKB/Swiss-Prot
    P00329
    UniProtKB/TrEMBL
    Q3UKA4
    Related
    ENSMUSP00000004232.10, ENSMUST00000004232.10
    Conserved Domains (2) summary
    cd08299
    Location:3375
    alcohol_DH_class_I_II_IV; class I, II, IV alcohol dehydrogenases
    COG1062
    Location:8375
    FrmA; Zn-dependent alcohol dehydrogenase [General function prediction only]

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    137983346..137996459
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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