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MALSU1 mitochondrial assembly of ribosomal large subunit 1 [ Homo sapiens (human) ]

Gene ID: 115416, updated on 7-Aug-2021

Summary

Official Symbol
MALSU1provided by HGNC
Official Full Name
mitochondrial assembly of ribosomal large subunit 1provided by HGNC
Primary source
HGNC:HGNC:21721
See related
Ensembl:ENSG00000156928 MIM:614624
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
mtRsfA; C7orf30
Expression
Ubiquitous expression in kidney (RPKM 9.8), fat (RPKM 9.6) and 25 other tissues See more
Orthologs
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Genomic context

See MALSU1 in Genome Data Viewer
Location:
7p15.3
Exon count:
5
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 7 NC_000007.14 (23298744..23311729)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (23338958..23351348)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101927890 Neighboring gene glycoprotein nmb Neighboring gene insulin like growth factor 2 mRNA binding protein 3 Neighboring gene small nucleolar RNA, C/D box 65C Neighboring gene RNA, U7 small nuclear 143 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables ribosomal large subunit binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in negative regulation of mitochondrial translation IDA
Inferred from Direct Assay
more info
PubMed 
involved_in negative regulation of ribosome biogenesis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in negative regulation of translation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in ribosomal large subunit biogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in cytosol IDA
Inferred from Direct Assay
more info
 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
mitochondrial assembly of ribosomal large subunit protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_138446.2NP_612455.1  mitochondrial assembly of ribosomal large subunit protein 1

    See identical proteins and their annotated locations for NP_612455.1

    Status: VALIDATED

    Source sequence(s)
    AC005082, BC012331
    Consensus CDS
    CCDS5381.1
    UniProtKB/Swiss-Prot
    Q96EH3
    Related
    ENSP00000419370.1, ENST00000466681.2
    Conserved Domains (1) summary
    pfam02410
    Location:98194
    RsfS; Ribosomal silencing factor during starvation

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p13 Primary Assembly

    Range
    23298744..23311729
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017011731.1XP_016867220.1  mitochondrial assembly of ribosomal large subunit protein 1 isoform X1

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