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Calcb calcitonin-related polypeptide, beta [ Mus musculus (house mouse) ]

Gene ID: 116903, updated on 23-Jun-2021

Summary

Official Symbol
Calcbprovided by MGI
Official Full Name
calcitonin-related polypeptide, betaprovided by MGI
Primary source
MGI:MGI:2151254
See related
Ensembl:ENSMUSG00000030666
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
CGR; Cal; CGRP2; Calc2
Expression
Biased expression in thymus adult (RPKM 2.1), large intestine adult (RPKM 0.5) and 13 other tissues See more
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Genomic context

See Calcb in Genome Data Viewer
Location:
7; 7 F1
Exon count:
5
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (114315790..114322603)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (114716555..114723368)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (121862157..121866879)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene Rho GTPase activating protein 21 pseudogene Neighboring gene ribosomal protein L5 pseudogene Neighboring gene INSC spindle orientation adaptor protein Neighboring gene predicted gene, 24982 Neighboring gene ribosomal protein S4-like, pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

General gene information

Markers

Clone Names

  • MGC130530

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables calcitonin receptor binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in adenylate cyclase-activating G protein-coupled receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in regulation of cytosolic calcium ion concentration IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
calcitonin gene-related peptide 2
Names
CGRP-II
beta-type CGRP
calcitonin gene-related peptide II

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_054084.2NP_473425.2  calcitonin gene-related peptide 2 precursor

    See identical proteins and their annotated locations for NP_473425.2

    Status: VALIDATED

    Source sequence(s)
    AI324836, BC111865
    Consensus CDS
    CCDS21764.1
    UniProtKB/TrEMBL
    Q3UW96
    Related
    ENSMUSP00000032902.5, ENSMUST00000032902.11
    Conserved Domains (1) summary
    pfam00214
    Location:1125
    Calc_CGRP_IAPP; Calcitonin / CGRP / IAPP family

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    114315790..114322603
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006507212.4XP_006507275.1  calcitonin gene-related peptide 2 isoform X1

    See identical proteins and their annotated locations for XP_006507275.1

    UniProtKB/TrEMBL
    Q3UW96
    Conserved Domains (1) summary
    pfam00214
    Location:1125
    Calc_CGRP_IAPP; Calcitonin / CGRP / IAPP family
  2. XM_006507213.4XP_006507276.1  calcitonin gene-related peptide 2 isoform X1

    See identical proteins and their annotated locations for XP_006507276.1

    UniProtKB/TrEMBL
    Q3UW96
    Conserved Domains (1) summary
    pfam00214
    Location:1125
    Calc_CGRP_IAPP; Calcitonin / CGRP / IAPP family
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