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Sv2b synaptic vesicle glycoprotein 2b [ Rattus norvegicus (Norway rat) ]

Gene ID: 117556, updated on 22-Aug-2021

Summary

Official Symbol
Sv2bprovided by RGD
Official Full Name
synaptic vesicle glycoprotein 2bprovided by RGD
Primary source
RGD:619716
See related
Ensembl:ENSRNOG00000011160
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
proton cotransporter; mediates the uptake of neurotransmitters into vesicles [RGD, Feb 2006]
Expression
Restricted expression toward (RPKM 462.5) See more
Orthologs
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Genomic context

See Sv2b in Genome Data Viewer
Location:
1q31
Exon count:
18
Annotation release Status Assembly Chr Location
108 current mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (128978471..129152479, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (136664199..136842247, complement)

Chromosome 1 - NC_051336.1Genomic Context describing neighboring genes Neighboring gene actin-like Neighboring gene 60S ribosomal protein L13-like Neighboring gene A-kinase anchoring protein 13 Neighboring gene uncharacterized LOC103691165

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in chemical synaptic transmission IEA
Inferred from Electronic Annotation
more info
 
involved_in neurotransmitter uptake TAS
Traceable Author Statement
more info
PubMed 
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
synaptic vesicle glycoprotein 2B
Names
synaptic vesicle protein 2B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_057207.3NP_476555.1  synaptic vesicle glycoprotein 2B

    See identical proteins and their annotated locations for NP_476555.1

    Status: VALIDATED

    Source sequence(s)
    AI716529, BF285601, BG671769, CB609053, CO402345, DV721065, L10362
    UniProtKB/Swiss-Prot
    Q63564
    Related
    ENSRNOT00000015084.6
    Conserved Domains (2) summary
    cd06174
    Location:112305
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    TIGR01299
    Location:8683
    synapt_SV2; synaptic vesicle protein SV2

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRatBN7.2 Primary Assembly

Genomic

  1. NC_051336.1 Reference mRatBN7.2 Primary Assembly

    Range
    128978471..129152479 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017588701.2XP_017444190.1  synaptic vesicle glycoprotein 2B isoform X1

    Conserved Domains (1) summary
    TIGR01299
    Location:8683
    synapt_SV2; synaptic vesicle protein SV2
  2. XM_008759493.3XP_008757715.1  synaptic vesicle glycoprotein 2B isoform X1

    See identical proteins and their annotated locations for XP_008757715.1

    Conserved Domains (1) summary
    TIGR01299
    Location:8683
    synapt_SV2; synaptic vesicle protein SV2
  3. XM_017588700.2XP_017444189.1  synaptic vesicle glycoprotein 2B isoform X1

    Conserved Domains (1) summary
    TIGR01299
    Location:8683
    synapt_SV2; synaptic vesicle protein SV2
  4. XM_039080109.1XP_038936037.1  synaptic vesicle glycoprotein 2B isoform X1

    Conserved Domains (1) summary
    TIGR01299
    Location:8683
    synapt_SV2; synaptic vesicle protein SV2
  5. XM_008759492.3XP_008757714.1  synaptic vesicle glycoprotein 2B isoform X1

    See identical proteins and their annotated locations for XP_008757714.1

    Conserved Domains (1) summary
    TIGR01299
    Location:8683
    synapt_SV2; synaptic vesicle protein SV2
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