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Cd5l CD5 antigen-like [ Mus musculus (house mouse) ]

Gene ID: 11801, updated on 9-Jan-2022

Summary

Official Symbol
Cd5lprovided by MGI
Official Full Name
CD5 antigen-likeprovided by MGI
Primary source
MGI:MGI:1334419
See related
Ensembl:ENSMUSG00000015854
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1/6; AIM; CT2; Pdp; Api6; mAIM; AAC-11; AI047839; Sp-alpha
Summary
Predicted to enable serine-type endopeptidase activity. Acts upstream of or within positive regulation of complement-dependent cytotoxicity and regulation of complement activation. Located in cell surface and plasma membrane. Is expressed in central nervous system; liver; retina; stomach; and testis. Orthologous to human CD5L (CD5 molecule like). [provided by Alliance of Genome Resources, Nov 2021]
Expression
Biased expression in liver E18 (RPKM 55.6), liver E14 (RPKM 35.5) and 4 other tissues See more
Orthologs
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Genomic context

See Cd5l in Genome Data Viewer
Location:
3; 3 F1
Exon count:
6
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (87265188..87278381)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (87357881..87371074)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 3 NC_000069.5 (87161803..87174996)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene Fc receptor-like S, scavenger receptor Neighboring gene predicted gene, 31879 Neighboring gene predicted gene, 31940 Neighboring gene Fc receptor-like 1 Neighboring gene predicted gene, 40084

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables scavenger receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables serine-type endopeptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in cell surface IDA
Inferred from Direct Assay
more info
PubMed 
located_in cell surface ISO
Inferred from Sequence Orthology
more info
PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
CD5 antigen-like
Names
AIM/Spalpha
CT-2
Pdp 1/6
apoptosis inhibitor 6
apoptosis inhibitor expressed by macrophages

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_009690.2NP_033820.2  CD5 antigen-like precursor

    See identical proteins and their annotated locations for NP_033820.2

    Status: VALIDATED

    Source sequence(s)
    AK159181, BY582711
    Consensus CDS
    CCDS17451.1
    UniProtKB/Swiss-Prot
    Q9QWK4
    Related
    ENSMUSP00000015998.7, ENSMUST00000015998.8
    Conserved Domains (2) summary
    smart00202
    Location:246348
    SR; Scavenger receptor Cys-rich
    pfam00530
    Location:251348
    SRCR; Scavenger receptor cysteine-rich domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    87265188..87278381
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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