Format

Send to:

Choose Destination

Apobec2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2 [ Mus musculus (house mouse) ]

Gene ID: 11811, updated on 23-Jun-2021

Summary

Official Symbol
Apobec2provided by MGI
Official Full Name
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2provided by MGI
Primary source
MGI:MGI:1343178
See related
Ensembl:ENSMUSG00000040694
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Arp1
Expression
Biased expression in heart adult (RPKM 62.8), mammary gland adult (RPKM 42.7) and 3 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Apobec2 in Genome Data Viewer
Location:
17 C; 17 24.02 cM
Exon count:
3
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (48726259..48739756, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (48419231..48432728, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 17 NC_000083.5 (48558556..48572053, complement)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene nuclear transcription factor-Y alpha Neighboring gene O-acyl-ADP-ribose deacylase 1 Neighboring gene predicted gene, 30283 Neighboring gene VISTA enhancer mm243 Neighboring gene translocator protein 2

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables catalytic activity IEA
Inferred from Electronic Annotation
more info
 
enables cytidine deaminase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables cytidine deaminase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables cytidine deaminase activity ISO
Inferred from Sequence Orthology
more info
PubMed 
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in DNA demethylation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in DNA demethylation ISO
Inferred from Sequence Orthology
more info
 
involved_in cytidine to uridine editing IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within cytidine to uridine editing IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within cytidine to uridine editing ISO
Inferred from Sequence Orthology
more info
PubMed 
acts_upstream_of_or_within mRNA modification IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within mRNA processing IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
C->U-editing enzyme APOBEC-2
Names
apolipoprotein B editing complex 2
mRNA(cytosine(6666)) deaminase 2
probable C->U-editing enzyme APOBEC-2
NP_033824.1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_009694.3NP_033824.1  C->U-editing enzyme APOBEC-2

    See identical proteins and their annotated locations for NP_033824.1

    Status: VALIDATED

    Source sequence(s)
    AC165291, AC166164
    Consensus CDS
    CCDS28868.1
    UniProtKB/Swiss-Prot
    Q9WV35
    Related
    ENSMUSP00000047402.4, ENSMUST00000046549.5
    Conserved Domains (3) summary
    cd01283
    Location:61151
    cytidine_deaminase; Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on ...
    pfam05240
    Location:160208
    APOBEC_C; APOBEC-like C-terminal domain
    pfam08210
    Location:52221
    APOBEC_N; APOBEC-like N-terminal domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    48726259..48739756 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Support Center