Format

Send to:

Choose Destination

Atp6v0c ATPase, H+ transporting, lysosomal V0 subunit C [ Mus musculus (house mouse) ]

Gene ID: 11984, updated on 23-Jun-2021

Summary

Official Symbol
Atp6v0cprovided by MGI
Official Full Name
ATPase, H+ transporting, lysosomal V0 subunit Cprovided by MGI
Primary source
MGI:MGI:88116
See related
Ensembl:ENSMUSG00000024121
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
A; At; PL; Atp; pro; Atp6; Atpl; PL16; VATL; Vma3; Atp6c; Atp6l; Atp6c2; Atpl-rs1
Expression
Ubiquitous expression in kidney adult (RPKM 768.5), adrenal adult (RPKM 629.5) and 28 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Atp6v0c in Genome Data Viewer
Location:
17; 17 A3.3
Exon count:
6
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (24382839..24388652, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (24163865..24169678, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 17 NC_000083.5 (24300833..24306374, complement)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene 3-phosphoinositide dependent protein kinase 1 Neighboring gene predicted gene, 33409 Neighboring gene amidohydrolase domain containing 2 Neighboring gene TBC1 domain family, member 24 Neighboring gene netrin 3 Neighboring gene tubulin epsilon and delta complex 2

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (3)  1 citation
  • Endonuclease-mediated (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables P-type proton-exporting transporter activity ISA
Inferred from Sequence Alignment
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables proton transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
enables ubiquitin protein ligase binding ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in Golgi apparatus ISO
Inferred from Sequence Orthology
more info
 
is_active_in integral component of membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in lysosome ISO
Inferred from Sequence Orthology
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
part_of proton-transporting V-type ATPase, V0 domain IEA
Inferred from Electronic Annotation
more info
 
part_of proton-transporting two-sector ATPase complex, proton-transporting domain IEA
Inferred from Electronic Annotation
more info
 
located_in synaptic vesicle ISO
Inferred from Sequence Orthology
more info
 
part_of vacuolar proton-transporting V-type ATPase complex TAS
Traceable Author Statement
more info
PubMed 
located_in vacuole IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
V-type proton ATPase 16 kDa proteolipid subunit
Names
ATPase, H+ transporting, lysosomal (vacuolar proton pump) 16 kDa
ATPase, H+ transporting, lysosomal 16kD, V0 subunit C
ATPase, H+ transporting, lysosomal 2
H(+)-ATPase (mvp)
V-ATPase 16 kDa proteolipid subunit
vacuolar proton pump 16 kDa proteolipid subunit
NP_001348460.1
NP_001348461.1
NP_001348462.1
NP_001348463.1
NP_001348464.1
NP_033859.1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001361531.1NP_001348460.1  V-type proton ATPase 16 kDa proteolipid subunit isoform a

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longest isoform (a).
    Source sequence(s)
    BP769833, BY140472, CT010502
    Conserved Domains (2) summary
    TIGR01100
    Location:72177
    V_ATP_synt_C; vacuolar ATP synthase 16 kDa proteolipid subunit
    pfam00137
    Location:152211
    ATP-synt_C; ATP synthase subunit C
  2. NM_001361532.1NP_001348461.1  V-type proton ATPase 16 kDa proteolipid subunit isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (b) is shorter at the N-terminus compared to isoform a. Variants 2 and 3 both encode the same isoform (b).
    Source sequence(s)
    CT010502
    Consensus CDS
    CCDS28476.1
    Related
    ENSMUSP00000111059.2, ENSMUST00000098862.9
    Conserved Domains (2) summary
    TIGR01100
    Location:13118
    V_ATP_synt_C; vacuolar ATP synthase 16 kDa proteolipid subunit
    cd18176
    Location:86153
    ATP-synt_Vo_c_ATP6C_rpt2; V-type proton ATPase 16 kDa proteolipid subunit (ATP6C/ATP6V0C/ATP6L/ATPL) and similar proteins
  3. NM_001361533.1NP_001348462.1  V-type proton ATPase 16 kDa proteolipid subunit isoform c

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (c) is shorter at the N-terminus compared to isoform a. Variants 4-6 all encode the same isoform (c).
    Source sequence(s)
    BY140472, CT010502
    Conserved Domains (2) summary
    cd18176
    Location:59126
    ATP-synt_Vo_c_ATP6C_rpt2; V-type proton ATPase 16 kDa proteolipid subunit (ATP6C/ATP6V0C/ATP6L/ATPL) and similar proteins
    cl00466
    Location:191
    ATP-synt_C; ATP synthase subunit C
  4. NM_001361534.1NP_001348463.1  V-type proton ATPase 16 kDa proteolipid subunit isoform c

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (c) is shorter at the N-terminus compared to isoform a. Variants 4-6 all encode the same isoform (c).
    Source sequence(s)
    CT010502
    Conserved Domains (2) summary
    cd18176
    Location:59126
    ATP-synt_Vo_c_ATP6C_rpt2; V-type proton ATPase 16 kDa proteolipid subunit (ATP6C/ATP6V0C/ATP6L/ATPL) and similar proteins
    cl00466
    Location:191
    ATP-synt_C; ATP synthase subunit C
  5. NM_001361535.1NP_001348464.1  V-type proton ATPase 16 kDa proteolipid subunit isoform c

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (c) is shorter at the N-terminus compared to isoform a. Variants 4-6 all encode the same isoform (c).
    Source sequence(s)
    BB873227, CT010502
    Conserved Domains (2) summary
    cd18176
    Location:59126
    ATP-synt_Vo_c_ATP6C_rpt2; V-type proton ATPase 16 kDa proteolipid subunit (ATP6C/ATP6V0C/ATP6L/ATPL) and similar proteins
    cl00466
    Location:191
    ATP-synt_C; ATP synthase subunit C
  6. NM_009729.4NP_033859.1  V-type proton ATPase 16 kDa proteolipid subunit isoform b

    See identical proteins and their annotated locations for NP_033859.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (b) is shorter at the N-terminus compared to isoform a. Variants 2 and 3 both encode the same isoform (b).
    Source sequence(s)
    AK002570, BC050939, BY245103
    Consensus CDS
    CCDS28476.1
    UniProtKB/Swiss-Prot
    P63082
    UniProtKB/TrEMBL
    A3KML5
    Related
    ENSMUSP00000024932.6, ENSMUST00000024932.12
    Conserved Domains (2) summary
    TIGR01100
    Location:13118
    V_ATP_synt_C; vacuolar ATP synthase 16 kDa proteolipid subunit
    cd18176
    Location:86153
    ATP-synt_Vo_c_ATP6C_rpt2; V-type proton ATPase 16 kDa proteolipid subunit (ATP6C/ATP6V0C/ATP6L/ATPL) and similar proteins

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    24382839..24388652 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Support Center