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Baat bile acid-Coenzyme A: amino acid N-acyltransferase [ Mus musculus (house mouse) ]

Gene ID: 12012, updated on 23-Jun-2021

Summary

Official Symbol
Baatprovided by MGI
Official Full Name
bile acid-Coenzyme A: amino acid N-acyltransferaseprovided by MGI
Primary source
MGI:MGI:106642
See related
Ensembl:ENSMUSG00000039653
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
BA; BAT; AI118337; AI158864
Expression
Biased expression in liver adult (RPKM 17.8), liver E18 (RPKM 3.3) and 1 other tissue See more
Orthologs
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Genomic context

See Baat in Genome Data Viewer
Location:
4 B1; 4 26.51 cM
Exon count:
4
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (49489416..49507915, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (49489416..49507915, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (49502290..49519430, complement)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene acyl-coenzyme A amino acid N-acyltransferase 1 Neighboring gene predicted gene, 26424 Neighboring gene predicted gene, 33009 Neighboring gene predicted gene, 32894 Neighboring gene predicted gene, 52736 Neighboring gene mitochondrial ribosomal protein L50

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Pathways from PubChem

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables N-acyltransferase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables N-acyltransferase activity ISO
Inferred from Sequence Orthology
more info
PubMed 
enables acyl-CoA hydrolase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables acyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables carboxylic ester hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables choloyl-CoA hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables glycine N-choloyltransferase activity ISO
Inferred from Sequence Orthology
more info
 
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables long-chain acyl-CoA hydrolase activity ISO
Inferred from Sequence Orthology
more info
 
enables medium-chain acyl-CoA hydrolase activity ISO
Inferred from Sequence Orthology
more info
 
enables myristoyl-CoA hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables palmitoyl-CoA hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables thiolester hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
enables very long chain acyl-CoA hydrolase activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in acyl-CoA metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in acyl-CoA metabolic process ISO
Inferred from Sequence Orthology
more info
 
involved_in bile acid biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
involved_in bile acid conjugation ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within bile acid metabolic process IDA
Inferred from Direct Assay
more info
PubMed 
involved_in fatty acid metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in glycine metabolic process ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within lipid metabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in taurine metabolic process ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
is_active_in peroxisome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in peroxisome ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
bile acid-CoA:amino acid N-acyltransferase
Names
BACAT
bile acid-CoA thioesterase
bile acid-Coenzyme A dehydrogenase: amino acid n-acyltransferase
choloyl-CoA hydrolase
glycine N-choloyltransferase
long-chain fatty-acyl-CoA hydrolase
taurine N-acyltransferase
NP_031545.2
XP_006537628.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_007519.3NP_031545.2  bile acid-CoA:amino acid N-acyltransferase

    See identical proteins and their annotated locations for NP_031545.2

    Status: VALIDATED

    Source sequence(s)
    AA255212, AK017923, BB800891, BY080271, CB947692, U95215
    Consensus CDS
    CCDS18173.1
    UniProtKB/Swiss-Prot
    Q91X34
    Related
    ENSMUSP00000041983.3, ENSMUST00000043056.9
    Conserved Domains (2) summary
    pfam08840
    Location:207414
    BAAT_C; BAAT / Acyl-CoA thioester hydrolase C terminal
    pfam04775
    Location:14140
    Bile_Hydr_Trans; Acyl-CoA thioester hydrolase/BAAT N-terminal region

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    49489416..49507915 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006537565.4XP_006537628.1  bile acid-CoA:amino acid N-acyltransferase isoform X1

    Conserved Domains (1) summary
    pfam08840
    Location:34241
    BAAT_C; BAAT / Acyl-CoA thioester hydrolase C terminal
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