Format

Send to:

Choose Destination

Bach2 BTB and CNC homology, basic leucine zipper transcription factor 2 [ Mus musculus (house mouse) ]

Gene ID: 12014, updated on 21-Oct-2021

Summary

Official Symbol
Bach2provided by MGI
Official Full Name
BTB and CNC homology, basic leucine zipper transcription factor 2provided by MGI
Primary source
MGI:MGI:894679
See related
Ensembl:ENSMUSG00000040270
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
E030004N02Rik
Expression
Broad expression in whole brain E14.5 (RPKM 5.3), CNS E14 (RPKM 5.0) and 24 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Bach2 in Genome Data Viewer
Location:
4; 4 A5
Exon count:
12
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (32238413..32586109)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (32238413..32586109)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (32504410..32673083)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene nuclear encoded tRNA glycine 3 (anticodon CCC) Neighboring gene VISTA enhancer mm720 Neighboring gene VISTA enhancer mm510 Neighboring gene BTB and CNC homology 2, opposite strand Neighboring gene caspase 8 associated protein 2 Neighboring gene gap junction protein, alpha 10

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (8)  1 citation
  • Chemically induced (ENU) (3) 
  • Endonuclease-mediated (3) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Clone Names

  • MGC117590

Gene Ontology Provided by MGI

Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
transcription regulator protein BACH2
Names
BTB and CNC homolog 2
BTB and CNC homology 2
Transcription regulator protein BACH2 (BTB and CNC homolog 2)

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001109661.1NP_001103131.1  transcription regulator protein BACH2

    See identical proteins and their annotated locations for NP_001103131.1

    Status: VALIDATED

    Source sequence(s)
    AL831746, BC131642, CX200493
    Consensus CDS
    CCDS51135.1
    UniProtKB/Swiss-Prot
    P97303
    Related
    ENSMUSP00000131592.2, ENSMUST00000171600.2
    Conserved Domains (2) summary
    cd14719
    Location:639709
    bZIP_BACH; Basic leucine zipper (bZIP) domain of BTB and CNC homolog (BACH) proteins: a DNA-binding and dimerization domain
    cd18278
    Location:6129
    BTB_POZ_BACH2; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in BTB and CNC homolog 2 (BACH2)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    32238413..32586109
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011249909.3XP_011248211.1  transcription regulator protein BACH2 isoform X2

    See identical proteins and their annotated locations for XP_011248211.1

    UniProtKB/Swiss-Prot
    P97303
    Related
    ENSMUSP00000103815.3, ENSMUST00000108180.9
    Conserved Domains (2) summary
    cd14719
    Location:639709
    bZIP_BACH; Basic leucine zipper (bZIP) domain of BTB and CNC homolog (BACH) proteins: a DNA-binding and dimerization domain
    cd18278
    Location:6129
    BTB_POZ_BACH2; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in BTB and CNC homolog 2 (BACH2)
  2. XM_030253112.2XP_030108972.1  transcription regulator protein BACH2 isoform X2

    Conserved Domains (2) summary
    cd14719
    Location:639709
    bZIP_BACH; Basic leucine zipper (bZIP) domain of BTB and CNC homolog (BACH) proteins: a DNA-binding and dimerization domain
    cd18278
    Location:6129
    BTB_POZ_BACH2; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in BTB and CNC homolog 2 (BACH2)
  3. XM_011249908.4XP_011248210.1  transcription regulator protein BACH2 isoform X1

    See identical proteins and their annotated locations for XP_011248210.1

    Conserved Domains (2) summary
    cd14719
    Location:646716
    bZIP_BACH; Basic leucine zipper (bZIP) domain of BTB and CNC homolog (BACH) proteins: a DNA-binding and dimerization domain
    cd18278
    Location:13136
    BTB_POZ_BACH2; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in BTB and CNC homolog 2 (BACH2)
  4. XM_006537566.5XP_006537629.1  transcription regulator protein BACH2 isoform X1

    See identical proteins and their annotated locations for XP_006537629.1

    Conserved Domains (2) summary
    cd14719
    Location:646716
    bZIP_BACH; Basic leucine zipper (bZIP) domain of BTB and CNC homolog (BACH) proteins: a DNA-binding and dimerization domain
    cd18278
    Location:13136
    BTB_POZ_BACH2; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in BTB and CNC homolog 2 (BACH2)
  5. XM_030253109.2XP_030108969.1  transcription regulator protein BACH2 isoform X1

    Conserved Domains (2) summary
    cd14719
    Location:646716
    bZIP_BACH; Basic leucine zipper (bZIP) domain of BTB and CNC homolog (BACH) proteins: a DNA-binding and dimerization domain
    cd18278
    Location:13136
    BTB_POZ_BACH2; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in BTB and CNC homolog 2 (BACH2)
  6. XM_036163607.1XP_036019500.1  transcription regulator protein BACH2 isoform X2

    Conserved Domains (2) summary
    cd14719
    Location:639709
    bZIP_BACH; Basic leucine zipper (bZIP) domain of BTB and CNC homolog (BACH) proteins: a DNA-binding and dimerization domain
    cd18278
    Location:6129
    BTB_POZ_BACH2; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in BTB and CNC homolog 2 (BACH2)
  7. XM_036163608.1XP_036019501.1  transcription regulator protein BACH2 isoform X2

    Conserved Domains (2) summary
    cd14719
    Location:639709
    bZIP_BACH; Basic leucine zipper (bZIP) domain of BTB and CNC homolog (BACH) proteins: a DNA-binding and dimerization domain
    cd18278
    Location:6129
    BTB_POZ_BACH2; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in BTB and CNC homolog 2 (BACH2)
  8. XM_006537567.5XP_006537630.1  transcription regulator protein BACH2 isoform X2

    See identical proteins and their annotated locations for XP_006537630.1

    UniProtKB/Swiss-Prot
    P97303
    Conserved Domains (2) summary
    cd14719
    Location:639709
    bZIP_BACH; Basic leucine zipper (bZIP) domain of BTB and CNC homolog (BACH) proteins: a DNA-binding and dimerization domain
    cd18278
    Location:6129
    BTB_POZ_BACH2; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in BTB and CNC homolog 2 (BACH2)
  9. XM_011249910.4XP_011248212.1  transcription regulator protein BACH2 isoform X3

    Conserved Domains (1) summary
    cd14719
    Location:522592
    bZIP_BACH; Basic leucine zipper (bZIP) domain of BTB and CNC homolog (BACH) proteins: a DNA-binding and dimerization domain

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_007521.3: Suppressed sequence

    Description
    NM_007521.3: This RefSeq was permanently suppressed because it represents a poorly supported variant with non-consensus splice sites.
Support Center