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pcbd1.S pterin-4 alpha-carbinolamine dehydratase 1 S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 121396288, updated on 19-Apr-2024

Summary

Official Symbol
pcbd1.S
Official Full Name
pterin-4 alpha-carbinolamine dehydratase 1 S homeolog
Primary source
Xenbase:XB-GENE-17331419
See related
EnsemblRapid:ENSXLAG00005005621
Gene type
protein coding
RefSeq status
MODEL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
pcd; phs; dcoh; pcbd; Xdcoh
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Genomic context

Location:
chromosome: 7S
Exon count:
5
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 7S NC_054384.1 (36434374..36442302)

Chromosome 7S - NC_054384.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 29 (equilibrative nucleoside transporter), member 3 S homeolog Neighboring gene uncharacterized LOC121396287 Neighboring gene unc-5 netrin receptor B S homeolog Neighboring gene uncharacterized LOC121396289 Neighboring gene pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha L homeolog

Genomic regions, transcripts, and products

Genomic Sequence:
NC_054384.1 Chromosome 7S Reference Xenopus_laevis_v10.1 Primary Assembly

General gene information

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables 4-alpha-hydroxytetrahydrobiopterin dehydratase activity IEA
Inferred from Electronic Annotation
more info
 
enables lyase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within tetrahydrobiopterin biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
pterin-4-alpha-carbinolamine dehydratase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054384.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    36434374..36442302
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041571130.1XP_041427064.1  pterin-4-alpha-carbinolamine dehydratase isoform X2

    UniProtKB/Swiss-Prot
    Q5D030, Q91901
    UniProtKB/TrEMBL
    A0A974HBJ9, Q5HZL2
    Conserved Domains (1) summary
    cd00914
    Location:2499
    PCD_DCoH_subfamily_b; PCD_DCoH: The bifunctional protein pterin-4alpha-carbinolamine dehydratase (PCD), also known as DCoH (dimerization cofactor of hepatocyte nuclear factor-1), is both a transcription activator and a metabolic enzyme. DCoH stimulates gene expression by ...
  2. XM_041571131.1XP_041427065.1  pterin-4-alpha-carbinolamine dehydratase isoform X3

    UniProtKB/TrEMBL
    A0A8J1LEG7
    Conserved Domains (1) summary
    cd00914
    Location:155
    PCD_DCoH_subfamily_b; PCD_DCoH: The bifunctional protein pterin-4alpha-carbinolamine dehydratase (PCD), also known as DCoH (dimerization cofactor of hepatocyte nuclear factor-1), is both a transcription activator and a metabolic enzyme. DCoH stimulates gene expression by ...
  3. XM_041571129.1XP_041427063.1  pterin-4-alpha-carbinolamine dehydratase isoform X1

    UniProtKB/Swiss-Prot
    Q5D030, Q91901
    UniProtKB/TrEMBL
    A0A8J1L9Z8
    Related
    ENSXLAP00005016611.1, ENSXLAT00005016907.1
    Conserved Domains (1) summary
    cd00914
    Location:30105
    PCD_DCoH_subfamily_b; PCD_DCoH: The bifunctional protein pterin-4alpha-carbinolamine dehydratase (PCD), also known as DCoH (dimerization cofactor of hepatocyte nuclear factor-1), is both a transcription activator and a metabolic enzyme. DCoH stimulates gene expression by ...