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Cacng2 calcium channel, voltage-dependent, gamma subunit 2 [ Mus musculus (house mouse) ]

Gene ID: 12300, updated on 8-Jul-2021

Summary

Official Symbol
Cacng2provided by MGI
Official Full Name
calcium channel, voltage-dependent, gamma subunit 2provided by MGI
Primary source
MGI:MGI:1316660
See related
Ensembl:ENSMUSG00000019146
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
sta; stg; wag; waggler; AW060990; stargazer; stargazin; B230105C07Rik; B930041E13Rik
Expression
Biased expression in cerebellum adult (RPKM 13.3), cortex adult (RPKM 7.7) and 4 other tissues See more
Orthologs
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Genomic context

See Cacng2 in Genome Data Viewer
Location:
15 E1; 15 36.92 cM
Exon count:
4
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (77876119..78004420, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (77991919..78120220, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 15 NC_000081.5 (77824053..77949710, complement)

Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene FAD-dependent oxidoreductase domain containing 2 Neighboring gene eukaryotic translation initiation factor 3, subunit D Neighboring gene predicted gene, 46520 Neighboring gene RIKEN cDNA A730060N03 gene Neighboring gene intraflagellar transport 27 Neighboring gene parvalbumin

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC123981

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables calcium channel activity IEA
Inferred from Electronic Annotation
more info
 
enables channel regulator activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables ionotropic glutamate receptor binding ISO
Inferred from Sequence Orthology
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables voltage-gated calcium channel activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables voltage-gated calcium channel activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables voltage-gated ion channel activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within calcium ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
involved_in calcium ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within calcium ion transport IEA
Inferred from Electronic Annotation
more info
 
involved_in calcium ion transport IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within ion transport IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within membrane depolarization IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within membrane hyperpolarization IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within nervous system process IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within neuromuscular junction development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in neurotransmitter receptor internalization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in neurotransmitter receptor internalization IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in neurotransmitter receptor localization to postsynaptic specialization membrane IDA
Inferred from Direct Assay
more info
PubMed 
involved_in neurotransmitter receptor localization to postsynaptic specialization membrane IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in neurotransmitter receptor transport, postsynaptic endosome to lysosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in neurotransmitter receptor transport, postsynaptic endosome to lysosome IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of AMPA receptor activity ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of protein localization to basolateral plasma membrane ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of synaptic transmission, glutamatergic IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in postsynaptic neurotransmitter receptor diffusion trapping IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in postsynaptic neurotransmitter receptor diffusion trapping IDA
Inferred from Direct Assay
more info
PubMed 
involved_in postsynaptic neurotransmitter receptor diffusion trapping IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in protein targeting to membrane ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of AMPA receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in regulation of AMPA receptor activity IDA
Inferred from Direct Assay
more info
PubMed 
involved_in regulation of AMPA receptor activity ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within regulation of ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within regulation of membrane potential IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of postsynaptic membrane neurotransmitter receptor levels IDA
Inferred from Direct Assay
more info
PubMed 
involved_in regulation of postsynaptic membrane neurotransmitter receptor levels IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in regulation of postsynaptic membrane neurotransmitter receptor levels IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of postsynaptic membrane neurotransmitter receptor levels IPI
Inferred from Physical Interaction
more info
PubMed 
involved_in transmission of nerve impulse IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within transmission of nerve impulse IGI
Inferred from Genetic Interaction
more info
PubMed 
Component Evidence Code Pubs
part_of AMPA glutamate receptor complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of AMPA glutamate receptor complex IDA
Inferred from Direct Assay
more info
PubMed 
part_of AMPA glutamate receptor complex ISO
Inferred from Sequence Orthology
more info
 
is_active_in Schaffer collateral - CA1 synapse IDA
Inferred from Direct Assay
more info
PubMed 
located_in cell junction IEA
Inferred from Electronic Annotation
more info
 
located_in cell surface ISO
Inferred from Sequence Orthology
more info
 
located_in cerebellar mossy fiber ISO
Inferred from Sequence Orthology
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
is_active_in glutamatergic synapse IDA
Inferred from Direct Assay
more info
PubMed 
located_in glutamatergic synapse IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in glutamatergic synapse IMP
Inferred from Mutant Phenotype
more info
PubMed 
located_in glutamatergic synapse IMP
Inferred from Mutant Phenotype
more info
PubMed 
is_active_in glutamatergic synapse IPI
Inferred from Physical Interaction
more info
PubMed 
located_in glutamatergic synapse IPI
Inferred from Physical Interaction
more info
PubMed 
is_active_in hippocampal mossy fiber to CA3 synapse IDA
Inferred from Direct Assay
more info
PubMed 
located_in hippocampal mossy fiber to CA3 synapse IDA
Inferred from Direct Assay
more info
PubMed 
located_in hippocampal mossy fiber to CA3 synapse IMP
Inferred from Mutant Phenotype
more info
PubMed 
located_in hippocampal mossy fiber to CA3 synapse IPI
Inferred from Physical Interaction
more info
PubMed 
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in integral component of postsynaptic density membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in neuron projection IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 
located_in postsynaptic density ISO
Inferred from Sequence Orthology
more info
 
is_active_in postsynaptic density membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in postsynaptic density membrane ISO
Inferred from Sequence Orthology
more info
 
located_in somatodendritic compartment IDA
Inferred from Direct Assay
more info
PubMed 
located_in synapse IEA
Inferred from Electronic Annotation
more info
 
part_of voltage-gated calcium channel complex IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
voltage-dependent calcium channel gamma-2 subunit
Names
TARP gamma-2
neuronal voltage-gated calcium channel gamma-2 subunit
transmembrane AMPAR regulatory protein gamma-2

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_007583.2NP_031609.1  voltage-dependent calcium channel gamma-2 subunit

    See identical proteins and their annotated locations for NP_031609.1

    Status: VALIDATED

    Source sequence(s)
    AL589650, BC103563
    Consensus CDS
    CCDS27608.1
    UniProtKB/Swiss-Prot
    O88602
    UniProtKB/TrEMBL
    Q3ZB20
    Related
    ENSMUSP00000019290.3, ENSMUST00000019290.3
    Conserved Domains (1) summary
    pfam00822
    Location:6197
    PMP22_Claudin; PMP-22/EMP/MP20/Claudin family

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000081.7 Reference GRCm39 C57BL/6J

    Range
    77876119..78004420 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006520371.3XP_006520434.1  voltage-dependent calcium channel gamma-2 subunit isoform X1

    Conserved Domains (1) summary
    cl21598
    Location:1174
    PMP22_Claudin; PMP-22/EMP/MP20/Claudin family
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