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Lhx5 LIM homeobox 5 [ Rattus norvegicus (Norway rat) ]

Gene ID: 124451, updated on 6-May-2021

Summary

Official Symbol
Lhx5provided by RGD
Official Full Name
LIM homeobox 5provided by RGD
Primary source
RGD:71079
See related
Ensembl:ENSRNOG00000001392
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
LIM homeobox transcription factor; may be involved in the topographic organization of motor neurons [RGD, Feb 2006]
Expression
Biased expression in Brain (RPKM 8.4) and Testes (RPKM 2.2) See more
Orthologs
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Genomic context

See Lhx5 in Genome Data Viewer
Location:
12q16
Exon count:
5
Annotation release Status Assembly Chr Location
108 current mRatBN7.2 (GCF_015227675.2) 12 NC_051347.1 (36126186..36134625, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 12 NC_005111.4 (41663000..41671437, complement)

Chromosome 12 - NC_051347.1Genomic Context describing neighboring genes Neighboring gene serine dehydratase Neighboring gene uncharacterized LOC108352452 Neighboring gene serine dehydratase-like Neighboring gene uncharacterized LOC120095980 Neighboring gene RNA binding motif protein 19

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
LIM/homeobox protein Lhx5
Names
LIM homeobox protein 5
homeobox protein LIM-2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_139036.2NP_620605.1  LIM/homeobox protein Lhx5

    See identical proteins and their annotated locations for NP_620605.1

    Status: VALIDATED

    Source sequence(s)
    JACYVU010000228
    UniProtKB/Swiss-Prot
    P61376
    Related
    ENSRNOP00000001883.2, ENSRNOT00000001883.3
    Conserved Domains (4) summary
    cd09367
    Location:556
    LIM1_Lhx1_Lhx5; The first LIM domain of Lhx1 (also known as Lim1) and Lhx5
    cd09375
    Location:64119
    LIM2_Lhx1_Lhx5; The second LIM domain of Lhx1 (also known as Lim1) and Lhx5
    PHA03378
    Location:247392
    PHA03378; EBNA-3B; Provisional
    pfam00046
    Location:183237
    Homeobox; Homeobox domain

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRatBN7.2 Primary Assembly

Genomic

  1. NC_051347.1 Reference mRatBN7.2 Primary Assembly

    Range
    36126186..36134625 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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