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Ms4a1 membrane-spanning 4-domains, subfamily A, member 1 [ Mus musculus (house mouse) ]

Gene ID: 12482, updated on 6-May-2021

Summary

Official Symbol
Ms4a1provided by MGI
Official Full Name
membrane-spanning 4-domains, subfamily A, member 1provided by MGI
Primary source
MGI:MGI:88321
See related
Ensembl:ENSMUSG00000024673
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Cd20; Ly-4; Ly-44; Ms4a2; AA960661
Expression
Biased expression in spleen adult (RPKM 13.9), mammary gland adult (RPKM 3.4) and 2 other tissues See more
Orthologs
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Genomic context

See Ms4a1 in Genome Data Viewer
Location:
19 A; 19 8.19 cM
Exon count:
7
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (11227043..11243513, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (11249679..11266149, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 19 NC_000085.5 (11325093..11340641, complement)

Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene membrane-spanning 4-domains, subfamily A, member 13 Neighboring gene RIKEN cDNA 4930526L06 gene Neighboring gene membrane-spanning 4-domains, subfamily A, member 12 Neighboring gene membrane-spanning 4-domains, subfamily A, member 5 Neighboring gene membrane-spanning 4-domains, subfamily A, member 14

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables epidermal growth factor receptor binding ISO
Inferred from Sequence Orthology
more info
 
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
 
enables immunoglobulin binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in B cell activation ISO
Inferred from Sequence Orthology
more info
 
involved_in B cell differentiation ISO
Inferred from Sequence Orthology
more info
 
involved_in B cell receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
 
involved_in calcium ion import into cytosol IDA
Inferred from Direct Assay
more info
PubMed 
involved_in calcium ion import into cytosol ISO
Inferred from Sequence Orthology
more info
 
involved_in protein tetramerization ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within response to bacterium IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in store-operated calcium entry ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in cell surface ISO
Inferred from Sequence Orthology
more info
 
located_in external side of plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in integral component of plasma membrane IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 
located_in plasma membrane raft ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
B-lymphocyte antigen CD20
Names
B-cell differentiation antigen Ly-44
CD20 antigen
lymphocyte antigen 44
membrane-spanning 4-domains, subfamily A, member 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_007641.6NP_031667.1  B-lymphocyte antigen CD20

    See identical proteins and their annotated locations for NP_031667.1

    Status: VALIDATED

    Source sequence(s)
    AK017903, AK080148, BE687007
    Consensus CDS
    CCDS37923.1
    UniProtKB/Swiss-Prot
    P19437
    UniProtKB/TrEMBL
    Q542S5
    Related
    ENSMUSP00000126422.2, ENSMUST00000169159.3
    Conserved Domains (1) summary
    pfam04103
    Location:44210
    CD20; CD20-like family

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000085.7 Reference GRCm39 C57BL/6J

    Range
    11227043..11243513 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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