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Cd8b1 CD8 antigen, beta chain 1 [ Mus musculus (house mouse) ]

Gene ID: 12526, updated on 23-Jun-2021

Summary

Official Symbol
Cd8b1provided by MGI
Official Full Name
CD8 antigen, beta chain 1provided by MGI
Primary source
MGI:MGI:88347
See related
Ensembl:ENSMUSG00000053044
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Ly-; Cd8b; Ly-3; Ly-C; Lyt-; Lyt-3
Expression
Restricted expression toward thymus adult (RPKM 247.7) See more
Orthologs
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Genomic context

See Cd8b1 in Genome Data Viewer
Location:
6 C1; 6 32.14 cM
Exon count:
6
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (71299772..71314476)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (71322788..71337492)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (71272806..71287445)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene predicted gene 1070 Neighboring gene predicted gene, 38828 Neighboring gene Cd8 alpha DNase I hypersensitive cluster CIV Neighboring gene Cd8 alpha DNase I hypersensitive cluster CIII Neighboring gene Cd8 alpha DNase I hypersensitive cluster CII Neighboring gene CD8 antigen, alpha chain

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Chemically induced (ENU) (2) 
  • Targeted (3)  1 citation

Pathways from PubChem

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables MHC class I protein binding IEA
Inferred from Electronic Annotation
more info
 
enables coreceptor activity IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within adaptive immune response IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within immune system process IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of immune response IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cell surface IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cell surface IDA
Inferred from Direct Assay
more info
PubMed 
located_in external side of plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
T-cell surface glycoprotein CD8 beta chain
Names
T-cell membrane glycoprotein Ly-3
T-cell surface glycoprotein Lyt-3
lymphocyte antigen 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_009858.3NP_033988.1  T-cell surface glycoprotein CD8 beta chain precursor

    See identical proteins and their annotated locations for NP_033988.1

    Status: VALIDATED

    Source sequence(s)
    AK162993, AK169581, BF023006, BY084951
    Consensus CDS
    CCDS39506.1
    UniProtKB/Swiss-Prot
    P10300
    UniProtKB/TrEMBL
    Q3TEK8
    Related
    ENSMUSP00000070131.8, ENSMUST00000065248.9
    Conserved Domains (2) summary
    cd07700
    Location:29135
    IgV_CD8_beta; Immunoglobulin (Ig) like domain of CD8 beta chain
    smart00410
    Location:26135
    IG_like; Immunoglobulin like

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    71299772..71314476
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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