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LOC126860105 BRD4-independent group 4 enhancer GRCh37_chr7:92324714-92325913 [ Homo sapiens (human) ]

Gene ID: 126860105, updated on 10-Oct-2023

Summary

Gene symbol
LOC126860105
Gene description
BRD4-independent group 4 enhancer GRCh37_chr7:92324714-92325913
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the STARR-seq (self-transcribing active regulatory region sequencing) massively parallel reporter assay in HCT116 colorectal carcinoma cells. This sequence was defined as a group 4 enhancer that depends on the BRD2, P300/CBP, MED14 and CDK7 cofactors, but it has limited or no dependence on the BRD4 bromodomain protein. [provided by RefSeq, Sep 2022]
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Genomic context

See LOC126860105 in Genome Data Viewer
Location:
chromosome: 7
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 7 NC_000007.14 (92695400..92696599)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 7 NC_060931.1 (93937370..93938569)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105375397 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18373 Neighboring gene Sharpr-MPRA regulatory region 6214 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26265 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26266 Neighboring gene uncharacterized LOC112268009 Neighboring gene cyclin dependent kinase 6 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26267 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26268 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26269 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26270 Neighboring gene RNA, U6 small nuclear 10, pseudogene Neighboring gene NANOG hESC enhancer GRCh37_chr7:92353193-92353749 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26271 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26272 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr7:92393426-92394053 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr7:92397855-92398394 Neighboring gene MPRA-validated peak6637 silencer Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26273 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr7:92438696-92439895 Neighboring gene H3K27ac hESC enhancer GRCh37_chr7:92462135-92462635 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18375 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26276 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18376 Neighboring gene CDK6 antisense RNA 1

Genomic regions, transcripts, and products

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_084606.1 

    Range
    101..1300
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p14 Primary Assembly

    Range
    92695400..92696599
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060931.1 Alternate T2T-CHM13v2.0

    Range
    93937370..93938569
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    GenBank, FASTA, Sequence Viewer (Graphics)