Format

Send to:

Choose Destination

Clca3a1 chloride channel accessory 3A1 [ Mus musculus (house mouse) ]

Gene ID: 12722, updated on 23-Jun-2021

Summary

Official Symbol
Clca3a1provided by MGI
Official Full Name
chloride channel accessory 3A1provided by MGI
Primary source
MGI:MGI:1316732
See related
Ensembl:ENSMUSG00000056025
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Clc; Cacc; Clca1
Expression
Broad expression in bladder adult (RPKM 11.5), liver E18 (RPKM 11.1) and 18 other tissues See more
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Clca3a1 in Genome Data Viewer
Location:
3 H2; 3 69.06 cM
Exon count:
16
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (144435438..144466738, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (144729677..144760977, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 3 NC_000069.5 (144393280..144423703, complement)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene SH3-domain GRB2-like B1 (endophilin) Neighboring gene BCL2/adenovirus E1B interacting protein 3 pseudogene Neighboring gene predicted gene, 34866 Neighboring gene nuclear receptor subfamily 5, group A, member 2 pseudogene Neighboring gene chloride channel accessory 3A2 Neighboring gene chloride channel accessory 3B Neighboring gene proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables intracellular calcium activated chloride channel activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables intracellular calcium activated chloride channel activity IDA
Inferred from Direct Assay
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables metallopeptidase activity IEA
Inferred from Electronic Annotation
more info
 
enables peptidase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within chloride transport IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within ion transport IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within proteolysis IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in integral component of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in integral component of plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
calcium-activated chloride channel regulator 3A-1
Names
chloride channel calcium activated 1
chloride channel calcium activated 3A1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_009899.4NP_034029.2  calcium-activated chloride channel regulator 3A-1 precursor

    See identical proteins and their annotated locations for NP_034029.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the functional protein.
    Source sequence(s)
    AC137128, AK137904, AK161805
    Consensus CDS
    CCDS17886.1
    UniProtKB/Swiss-Prot
    Q9QX15
    Related
    ENSMUSP00000054526.6, ENSMUST00000059091.6
    Conserved Domains (1) summary
    TIGR00868
    Location:1865
    hCaCC; calcium-activated chloride channel protein 1

RNA

  1. NR_130895.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an alternate internal exon, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most supported translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC137128, AK137904, AK161805
    Related
    ENSMUST00000029932.14

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    144435438..144466738 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011240004.1XP_011238306.1  calcium-activated chloride channel regulator 3A-1 isoform X2

    Conserved Domains (1) summary
    TIGR00868
    Location:35714
    hCaCC; calcium-activated chloride channel protein 1
  2. XM_006500965.5XP_006501028.1  calcium-activated chloride channel regulator 3A-1 isoform X1

    Conserved Domains (1) summary
    TIGR00868
    Location:1788
    hCaCC; calcium-activated chloride channel protein 1

RNA

  1. XR_004941270.1 RNA Sequence

  2. XR_003954276.2 RNA Sequence

Support Center