COL8A2 - collagen type VIII alpha 2 chain
This gene encodes the alpha 2 chain of type VIII collagen. This protein is a major component of the basement membrane of the corneal endothelium and forms homo- or heterotrimers with alpha 1 (VIII) type collagens. Defects in this gene are associated with Fuchs endothelial corneal dystrophy and posterior polymorphous corneal dystrophy type 2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]
NCBI Orthologs
How was this calculated?genes for:
Protein alignment
Download data
Species | Gene | Architecture | aa |
---|