Format

Send to:

Choose Destination

Csf2rb colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) [ Mus musculus (house mouse) ]

Gene ID: 12983, updated on 25-Nov-2021

Summary

Official Symbol
Csf2rbprovided by MGI
Official Full Name
colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)provided by MGI
Primary source
MGI:MGI:1339759
See related
Ensembl:ENSMUSG00000071713
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Bc; Il3r; AIC2B; Il3rb; Il5rb; CDw131; Il3rb1; Csf2rb1; Csfgmrb; AI848964
Expression
Broad expression in mammary gland adult (RPKM 30.9), spleen adult (RPKM 19.6) and 16 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Csf2rb in Genome Data Viewer
Location:
15 E1; 15 37.36 cM
Exon count:
15
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (78210000..78235201)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (78325800..78351001)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 15 NC_000081.5 (78156420..78181431)

Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene neutrophil cytosolic factor 4 Neighboring gene microRNA 7676-1 Neighboring gene colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage) Neighboring gene microRNA 7676-2 Neighboring gene testis expressed 33 Neighboring gene thiosulfate sulfurtransferase, mitochondrial

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC130522

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables cytokine receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables cytokine receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
is_active_in external side of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of granulocyte macrophage colony-stimulating factor receptor complex ISO
Inferred from Sequence Orthology
more info
 
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
cytokine receptor common subunit beta
Names
CD131 antigen
GM-CSF/IL-3/IL-5 receptor common beta subunit
GM-CSF/IL-3/IL-5 receptor common beta-chain
beta c
colony stimulating factor 2 receptor, beta 1, low-affinity (granulocyte-macrophage)
common beta chain

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001358854.1NP_001345783.1  cytokine receptor common subunit beta precursor

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    AL583893
    Consensus CDS
    CCDS27612.1
    Related
    ENSMUSP00000154836.2, ENSMUST00000230264.3
    Conserved Domains (3) summary
    cd00063
    Location:346439
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cl21522
    Location:250316
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cl26464
    Location:551809
    Atrophin-1; Atrophin-1 family
  2. NM_007780.4NP_031806.3  cytokine receptor common subunit beta precursor

    See identical proteins and their annotated locations for NP_031806.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    AI467222, AK152608, AL583893
    Consensus CDS
    CCDS27612.1
    UniProtKB/Swiss-Prot
    P26955
    Related
    ENSMUSP00000094082.4, ENSMUST00000096355.4
    Conserved Domains (3) summary
    cd00063
    Location:346439
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cl21522
    Location:250316
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cl26464
    Location:551809
    Atrophin-1; Atrophin-1 family

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000081.7 Reference GRCm39 C57BL/6J

    Range
    78210000..78235201
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Support Center