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Csf2rb2 colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage) [ Mus musculus (house mouse) ]

Gene ID: 12984, updated on 23-Jun-2021

Summary

Official Symbol
Csf2rb2provided by MGI
Official Full Name
colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)provided by MGI
Primary source
MGI:MGI:1339760
See related
Ensembl:ENSMUSG00000071714
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
I; AI; Bi; Il3; Bil3; Il3r; AIC2A; Il3rb; Il3rb2; BetaIl3; Csfgmrb
Expression
Broad expression in mammary gland adult (RPKM 26.5), spleen adult (RPKM 9.9) and 15 other tissues See more
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Genomic context

See Csf2rb2 in Genome Data Viewer
Location:
15 E1; 15 37.22 cM
Exon count:
14
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (78166707..78189921, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (78282507..78305721, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 15 NC_000081.5 (78112940..78136033, complement)

Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene parvalbumin Neighboring gene neutrophil cytosolic factor 4 Neighboring gene microRNA 7676-1 Neighboring gene colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) Neighboring gene microRNA 7676-2 Neighboring gene testis expressed 33

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables cytokine receptor activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in cytokine-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
interleukin-3 receptor class 2 subunit beta
Names
IL-3 receptor class 2 subunit beta
IL-3R class 2 subunit beta
colony-stimulating factor 2 receptor subunit beta-2
interleukin-3 receptor class II beta chain

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001287389.1NP_001274318.1  interleukin-3 receptor class 2 subunit beta isoform 2 precursor

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks two alternate exons in the coding region compared to variant 1. The resulting protein (isoform 2) is shorter but has the same N- and C-termini compared to isoform 1.
    Source sequence(s)
    AK155626, AL589692, BY208313
    Consensus CDS
    CCDS88799.1
    UniProtKB/TrEMBL
    Q3U1Z1
    Related
    ENSMUSP00000155013.3, ENSMUST00000230115.3
    Conserved Domains (2) summary
    cd00063
    Location:245329
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cl21522
    Location:140218
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
  2. NM_007781.3NP_031807.1  interleukin-3 receptor class 2 subunit beta isoform 1 precursor

    See identical proteins and their annotated locations for NP_031807.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer protein (isoform 1).
    Source sequence(s)
    AL589692
    Consensus CDS
    CCDS27611.1
    UniProtKB/Swiss-Prot
    P26954
    Related
    ENSMUSP00000094083.4, ENSMUST00000096356.5
    Conserved Domains (3) summary
    smart00060
    Location:137225
    FN3; Fibronectin type 3 domain
    cd00063
    Location:354438
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cl21522
    Location:249327
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000081.7 Reference GRCm39 C57BL/6J

    Range
    78166707..78189921 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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