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Dpep1 dipeptidase 1 [ Mus musculus (house mouse) ]

Gene ID: 13479, updated on 6-Sep-2021

Summary

Official Symbol
Dpep1provided by MGI
Official Full Name
dipeptidase 1provided by MGI
Primary source
MGI:MGI:94917
See related
Ensembl:ENSMUSG00000019278
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
MBD; DPEP-1; AI327012
Expression
Biased expression in large intestine adult (RPKM 182.7), small intestine adult (RPKM 109.8) and 11 other tissues See more
Orthologs
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Genomic context

See Dpep1 in Genome Data Viewer
Location:
8 E1; 8 72.08 cM
Exon count:
11
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (123912974..123928551)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (123186235..123201812)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (125710135..125725712)

Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC118567625 Neighboring gene predicted gene 4316 Neighboring gene charged multivesicular body protein 1A Neighboring gene ribosomal protein S12, pseudogene 9 Neighboring gene spermatogenesis associated 33

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1)  1 citation
  • Endonuclease-mediated (1) 

Pathways from PubChem

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables beta-lactamase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables beta-lactamase activity ISO
Inferred from Sequence Orthology
more info
 
enables cysteine-type endopeptidase inhibitor activity involved in apoptotic process ISO
Inferred from Sequence Orthology
more info
 
enables dipeptidase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables dipeptidase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables metallodipeptidase activity ISO
Inferred from Sequence Orthology
more info
 
enables metallopeptidase activity IEA
Inferred from Electronic Annotation
more info
 
enables modified amino acid binding ISO
Inferred from Sequence Orthology
more info
 
enables peptidase activity IEA
Inferred from Electronic Annotation
more info
 
enables zinc ion binding ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in anchored component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in apical part of cell ISO
Inferred from Sequence Orthology
more info
 
located_in cell junction ISO
Inferred from Sequence Orthology
more info
 
located_in cell projection IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
dipeptidase 1
Names
MBD-1
beta-lactamase
dipeptidase 1 (renal)
membrane bound dipeptidase type II
membrane-bound dipeptidase 1
microsomal dipeptidase
renal dipeptidase
NP_031902.2
XP_017168047.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_007876.2NP_031902.2  dipeptidase 1 precursor

    See identical proteins and their annotated locations for NP_031902.2

    Status: VALIDATED

    Source sequence(s)
    AI482156, AK002380, AK132644, BY229517, D13139
    Consensus CDS
    CCDS22750.1
    UniProtKB/Swiss-Prot
    P31428
    UniProtKB/TrEMBL
    Q3V175
    Related
    ENSMUSP00000019422.5, ENSMUST00000019422.6
    Conserved Domains (1) summary
    pfam01244
    Location:25352
    Peptidase_M19; Membrane dipeptidase (Peptidase family M19)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000074.7 Reference GRCm39 C57BL/6J

    Range
    123912974..123928551
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017312558.2XP_017168047.1  dipeptidase 1 isoform X1

    UniProtKB/Swiss-Prot
    P31428
    Conserved Domains (1) summary
    pfam01244
    Location:25352
    Peptidase_M19; Membrane dipeptidase (Peptidase family M19)
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