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Dpm2 dolichol-phosphate (beta-D) mannosyltransferase 2 [ Mus musculus (house mouse) ]

Gene ID: 13481, updated on 23-Jun-2021

Summary

Official Symbol
Dpm2provided by MGI
Official Full Name
dolichol-phosphate (beta-D) mannosyltransferase 2provided by MGI
Primary source
MGI:MGI:1330238
See related
Ensembl:ENSMUSG00000026810
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
R75484; AW557993
Expression
Ubiquitous expression in adrenal adult (RPKM 57.3), large intestine adult (RPKM 53.3) and 28 other tissues See more
Orthologs
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Genomic context

See Dpm2 in Genome Data Viewer
Location:
2; 2 B
Exon count:
4
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (32460870..32463583)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (32570858..32573571)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (32426378..32429091)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25 Neighboring gene nuclear apoptosis inducing factor 1 Neighboring gene family with sequence similarity 102, member A Neighboring gene RIKEN cDNA 9430097D07 gene Neighboring gene phosphatidylinositol-4-phosphate 5-kinase-like 1 Neighboring gene ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 Neighboring gene predicted gene, 52551 Neighboring gene predicted gene, 23369

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables dolichyl-phosphate beta-D-mannosyltransferase activity ISO
Inferred from Sequence Orthology
more info
PubMed 
enables enzyme activator activity ISO
Inferred from Sequence Orthology
more info
 
enables enzyme regulator activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables enzyme regulator activity ISO
Inferred from Sequence Orthology
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in GPI anchor biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within GPI anchor biosynthetic process ISO
Inferred from Sequence Orthology
more info
PubMed 
involved_in GPI anchor biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within dolichol metabolic process ISO
Inferred from Sequence Orthology
more info
PubMed 
involved_in regulation of protein stability ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
part_of dolichol-phosphate-mannose synthase complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of dolichol-phosphate-mannose synthase complex ISO
Inferred from Sequence Orthology
more info
PubMed 
colocalizes_with endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
 
located_in endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
PubMed 
part_of glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex ISO
Inferred from Sequence Orthology
more info
 
located_in integral component of endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 
located_in integral component of membrane ISM
Inferred from Sequence Model
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in perinuclear region of cytoplasm ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
dolichol phosphate-mannose biosynthesis regulatory protein
Names
DPM synthase subunit 2
dolichol-phosphate mannose synthase subunit 2
NP_034203.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_010073.2NP_034203.1  dolichol phosphate-mannose biosynthesis regulatory protein

    See identical proteins and their annotated locations for NP_034203.1

    Status: VALIDATED

    Source sequence(s)
    BC008256
    Consensus CDS
    CCDS38104.1
    UniProtKB/Swiss-Prot
    Q9Z324
    UniProtKB/TrEMBL
    Q545R7
    Related
    ENSMUSP00000028151.7, ENSMUST00000028151.7
    Conserved Domains (1) summary
    pfam07297
    Location:578
    DPM2; Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    32460870..32463583
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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