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Eef1a2 eukaryotic translation elongation factor 1 alpha 2 [ Mus musculus (house mouse) ]

Gene ID: 13628, updated on 8-Jul-2021

Summary

Official Symbol
Eef1a2provided by MGI
Official Full Name
eukaryotic translation elongation factor 1 alpha 2provided by MGI
Primary source
MGI:MGI:1096317
See related
Ensembl:ENSMUSG00000016349
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
S; S1; STN; wst; Eef1; Eef1a; EEF1AL; wasted; EF-1-alpha-2
Expression
Biased expression in heart adult (RPKM 359.9), cerebellum adult (RPKM 338.2) and 6 other tissues See more
Orthologs
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Genomic context

See Eef1a2 in Genome Data Viewer
Location:
2 H4; 2 103.6 cM
Exon count:
8
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (180783551..180798808, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (181141758..181157015, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (180882397..180891720, complement)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene cholinergic receptor, nicotinic, alpha polypeptide 4 Neighboring gene potassium voltage-gated channel, subfamily Q, member 2 Neighboring gene predicted gene, 24892 Neighboring gene pancreatic progenitor cell differentiation and proliferation factor

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Spontaneous (1) 
  • Endonuclease-mediated (1) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
 
enables GTPase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables protein kinase binding ISO
Inferred from Sequence Orthology
more info
 
enables translation elongation factor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables translation elongation factor activity IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within positive regulation of apoptotic process IDA
Inferred from Direct Assay
more info
PubMed 
involved_in positive regulation of lipid kinase activity ISO
Inferred from Sequence Orthology
more info
 
involved_in translation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in translational elongation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within translational elongation IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
part_of eukaryotic translation elongation factor 1 complex IDA
Inferred from Direct Assay
more info
PubMed 
located_in myelin sheath HDA PubMed 
located_in neuronal cell body ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
located_in synapse EXP
Inferred from Experiment
more info
PubMed 
is_active_in synapse IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
elongation factor 1-alpha 2
Names
eukaryotic elongation factor 1 A-2
statin-S1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_007906.3NP_031932.1  elongation factor 1-alpha 2

    See identical proteins and their annotated locations for NP_031932.1

    Status: VALIDATED

    Source sequence(s)
    AL450341, BC018235, BC060606, BE656626
    Consensus CDS
    CCDS17201.1
    UniProtKB/Swiss-Prot
    P62631
    Related
    ENSMUSP00000054556.8, ENSMUST00000055990.8
    Conserved Domains (1) summary
    PTZ00141
    Location:1460
    PTZ00141; elongation factor 1- alpha; Provisional

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    180783551..180798808 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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