Format

Send to:

Choose Destination

Wfdc18 WAP four-disulfide core domain 18 [ Mus musculus (house mouse) ]

Gene ID: 14038, updated on 23-Jun-2021

Summary

Official Symbol
Wfdc18provided by MGI
Official Full Name
WAP four-disulfide core domain 18provided by MGI
Primary source
MGI:MGI:107506
See related
Ensembl:ENSMUSG00000000983
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Ex; Ka; Expi; Kal1; WDNM; WDNM1
Expression
Biased expression in mammary gland adult (RPKM 18.3), thymus adult (RPKM 11.0) and 4 other tissues See more
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Wfdc18 in Genome Data Viewer
Location:
11; 11 C
Exon count:
3
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (83599830..83602186)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (83709004..83711360)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (83522506..83524862)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene predicted gene 11430 Neighboring gene WAP four-disulfide core domain 17 Neighboring gene WAP four-disulfide core domain 21 Neighboring gene HEAT repeat containing 6

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables peptidase inhibitor activity IEA
Inferred from Electronic Annotation
more info
 
enables serine-type endopeptidase inhibitor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in antibacterial humoral response IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in innate immune response IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within negative regulation of peptidase activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
WAP four-disulfide core domain protein 18
Names
Kallmann syndrome 1 sequence
extracellular peptidase inhibitor
extracellular proteinase inhibitor

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_007969.4NP_031995.3  WAP four-disulfide core domain protein 18 precursor

    See identical proteins and their annotated locations for NP_031995.3

    Status: VALIDATED

    Source sequence(s)
    EH099462, EH105860, EH109450
    Consensus CDS
    CCDS25175.1
    UniProtKB/Swiss-Prot
    P62810
    Related
    ENSMUSP00000001009.8, ENSMUST00000001009.14
    Conserved Domains (1) summary
    cd00199
    Location:1473
    WAP; whey acidic protein-type four-disulfide core domains. Members of the family include whey acidic protein, elafin (elastase-specific inhibitor), caltrin-like protein (a calcium transport inhibitor) and other extracellular proteinase inhibitors. A group of ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    83599830..83602186
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Support Center