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Msmo1 methylsterol monooxygenase 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 140910, updated on 7-Aug-2021

Summary

Official Symbol
Msmo1provided by RGD
Official Full Name
methylsterol monooxygenase 1provided by RGD
Primary source
RGD:620281
See related
Ensembl:ENSRNOG00000032297
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Sc4mol
Summary
may be involved in the repair process of nerve tissues [RGD, Feb 2006]
Expression
Biased expression in Liver (RPKM 757.0), Brain (RPKM 458.9) and 9 other tissues See more
Orthologs
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Genomic context

See Msmo1 in Genome Data Viewer
Location:
16p13
Exon count:
6
Annotation release Status Assembly Chr Location
108 current mRatBN7.2 (GCF_015227675.2) 16 NC_051351.1 (24980680..24997927)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 16 NC_005115.4 (26859441..26875880)

Chromosome 16 - NC_051351.1Genomic Context describing neighboring genes Neighboring gene transmembrane protein 192 Neighboring gene kelch-like family member 2 Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC120097471 Neighboring gene carboxypeptidase E

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

Pathways from PubChem

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables C-4 methylsterol oxidase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
 
enables oxidoreductase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in cholesterol biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
involved_in sterol biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
methylsterol monooxygenase 1
Names
C-4 methylsterol oxidase
RANP-1
neuropep 1
neurorep 1
sterol-C4-methyl oxidase
NP_543162.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_080886.1NP_543162.1  methylsterol monooxygenase 1

    See identical proteins and their annotated locations for NP_543162.1

    Status: PROVISIONAL

    Source sequence(s)
    D50559
    UniProtKB/Swiss-Prot
    O35532
    Related
    ENSRNOP00000043782.1, ENSRNOT00000044171.2
    Conserved Domains (1) summary
    pfam04116
    Location:143274
    FA_hydroxylase; Fatty acid hydroxylase superfamily

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRatBN7.2 Primary Assembly

Genomic

  1. NC_051351.1 Reference mRatBN7.2 Primary Assembly

    Range
    24980680..24997927
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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