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Slco3a1 solute carrier organic anion transporter family, member 3a1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 140915, updated on 30-Sep-2021

Summary

Official Symbol
Slco3a1provided by RGD
Official Full Name
solute carrier organic anion transporter family, member 3a1provided by RGD
Primary source
RGD:620227
See related
EnsemblRapid:ENSRNOG00000032798
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Slc21a11
Summary
transports several types of prostaglandins; may play a role in prostaglandin transport in vascular, renal, and reproductive systems [RGD, Feb 2006]
Expression
Biased expression in Heart (RPKM 55.4), Lung (RPKM 41.4) and 8 other tissues See more
Orthologs
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Genomic context

See Slco3a1 in Genome Data Viewer
Location:
1q31
Exon count:
10
Annotation release Status Assembly Chr Location
108 current mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (128115184..128387887, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (135790854..136073640, complement)

Chromosome 1 - NC_051336.1Genomic Context describing neighboring genes Neighboring gene U1 spliceosomal RNA Neighboring gene hypothetical protein LOC100360396 Neighboring gene actin-like Neighboring gene 60S ribosomal protein L13-like

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Pathways from PubChem

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables sodium-independent organic anion transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in ion transport IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of NF-kappaB transcription factor activity IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of NF-kappaB transcription factor activity ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of protein phosphorylation ISO
Inferred from Sequence Orthology
more info
 
involved_in prostaglandin transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in prostaglandin transport IDA
Inferred from Direct Assay
more info
PubMed 
involved_in prostaglandin transport IEA
Inferred from Electronic Annotation
more info
 
involved_in prostaglandin transport ISO
Inferred from Sequence Orthology
more info
 
involved_in sodium-independent organic anion transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in integral component of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
solute carrier organic anion transporter family member 3A1
Names
OATP-D
organic anion-transporting polypeptide D
prostaglandin transporter subtype 2
sodium-independent organic anion transporter D
solute carrier family 21 (organic anion transporter), member 11
solute carrier family 21 member 11

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_177481.1NP_803434.1  solute carrier organic anion transporter family member 3A1

    See identical proteins and their annotated locations for NP_803434.1

    Status: PROVISIONAL

    Source sequence(s)
    AF239219
    UniProtKB/Swiss-Prot
    Q99N02
    Related
    ENSRNOP00000074908.2, ENSRNOT00000082564.2
    Conserved Domains (3) summary
    cd06174
    Location:47286
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    cd01330
    Location:467511
    KAZAL_SLC21; The kazal-type serine protease inhibitor domain has been detected in an extracellular loop region of solute carrier 21 (SLC21) family members (organic anion transporters) , which may regulate the specificity of anion uptake. The KAZAL_SLC21 domain is a ...
    pfam03137
    Location:41619
    OATP; Organic Anion Transporter Polypeptide (OATP) family

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRatBN7.2 Primary Assembly

Genomic

  1. NC_051336.1 Reference mRatBN7.2 Primary Assembly

    Range
    128115184..128387887 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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