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Ftcd formiminotransferase cyclodeaminase [ Mus musculus (house mouse) ]

Gene ID: 14317, updated on 23-Jun-2021

Summary

Official Symbol
Ftcdprovided by MGI
Official Full Name
formiminotransferase cyclodeaminaseprovided by MGI
Primary source
MGI:MGI:1339962
See related
Ensembl:ENSMUSG00000001155
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Expression
Biased expression in liver adult (RPKM 178.1), liver E18 (RPKM 58.0) and 2 other tissues See more
Orthologs
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Genomic context

See Ftcd in Genome Data Viewer
Location:
10 C1; 10 39.25 cM
Exon count:
15
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (76411482..76426172)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (76575648..76590338)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (76038393..76053083)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4930483K19 gene Neighboring gene lanosterol synthase Neighboring gene spermatogenesis and centriole associated 1 like Neighboring gene predicted gene 15343 Neighboring gene collagen, type VI, alpha 2 Neighboring gene predicted gene, 51774

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables catalytic activity IEA
Inferred from Electronic Annotation
more info
 
enables folic acid binding IEA
Inferred from Electronic Annotation
more info
 
enables formimidoyltetrahydrofolate cyclodeaminase activity ISO
Inferred from Sequence Orthology
more info
 
enables formimidoyltetrahydrofolate cyclodeaminase activity TAS
Traceable Author Statement
more info
PubMed 
enables glutamate formimidoyltransferase activity ISO
Inferred from Sequence Orthology
more info
 
enables glutamate formimidoyltransferase activity TAS
Traceable Author Statement
more info
PubMed 
enables lyase activity IEA
Inferred from Electronic Annotation
more info
 
enables microtubule binding ISO
Inferred from Sequence Orthology
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in cellular metabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in cytoskeleton organization ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within histidine catabolic process TAS
Traceable Author Statement
more info
PubMed 
acts_upstream_of_or_within histidine metabolic process IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within metabolic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in Golgi apparatus IDA
Inferred from Direct Assay
more info
PubMed 
located_in Golgi apparatus ISO
Inferred from Sequence Orthology
more info
 
located_in Golgi membrane ISO
Inferred from Sequence Orthology
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
 
located_in endoplasmic reticulum-Golgi intermediate compartment ISO
Inferred from Sequence Orthology
more info
 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 
located_in smooth endoplasmic reticulum membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
formimidoyltransferase-cyclodeaminase
Names
glutamate formiminotransferase
NP_543121.1
XP_006513278.1
XP_006513279.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_080845.2NP_543121.1  formimidoyltransferase-cyclodeaminase

    See identical proteins and their annotated locations for NP_543121.1

    Status: VALIDATED

    Source sequence(s)
    AK165414, BB610765, CB949427, CD297973
    Consensus CDS
    CCDS23950.1
    UniProtKB/Swiss-Prot
    Q91XD4
    Related
    ENSMUSP00000001183.8, ENSMUST00000001183.8
    Conserved Domains (2) summary
    TIGR02024
    Location:1328
    FtcD; glutamate formiminotransferase
    pfam04961
    Location:340519
    FTCD_C; Formiminotransferase-cyclodeaminase

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    76411482..76426172
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006513216.3XP_006513279.1  formimidoyltransferase-cyclodeaminase isoform X2

    Conserved Domains (3) summary
    pfam02971
    Location:32175
    FTCD; Formiminotransferase domain
    pfam04961
    Location:190363
    FTCD_C; Formiminotransferase-cyclodeaminase
    cl26845
    Location:430
    FTCD_N; Formiminotransferase domain, N-terminal subdomain
  2. XM_006513215.3XP_006513278.1  formimidoyltransferase-cyclodeaminase isoform X1

    Conserved Domains (2) summary
    pfam04961
    Location:323496
    FTCD_C; Formiminotransferase-cyclodeaminase
    cl26845
    Location:2312
    FTCD_N; Formiminotransferase domain, N-terminal subdomain
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