Format

Send to:

Choose Destination

Ptgdr2 prostaglandin D2 receptor 2 [ Mus musculus (house mouse) ]

Gene ID: 14764, updated on 28-Nov-2021

Summary

Official Symbol
Ptgdr2provided by MGI
Official Full Name
prostaglandin D2 receptor 2provided by MGI
Primary source
MGI:MGI:1330275
See related
Ensembl:ENSMUSG00000034117
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Crth2; Gpr44; Grp45
Expression
Broad expression in ovary adult (RPKM 2.6), subcutaneous fat pad adult (RPKM 1.9) and 15 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Ptgdr2 in Genome Data Viewer
Location:
19; 19 A
Exon count:
7
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (10901883..10919875)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (10924519..10942511)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 19 NC_000085.5 (11011650..11017001)

Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene pre-mRNA processing factor 19 Neighboring gene zona pellucida glycoprotein 1 Neighboring gene coiled-coil domain containing 86 Neighboring gene membrane-spanning 4-domains, subfamily A, member 10 Neighboring gene membrane-spanning 4-domains, subfamily A, member 15

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

General gene information

Homology

Clone Names

  • MGC130436

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables G protein-coupled receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables G protein-coupled receptor activity IDA
Inferred from Direct Assay
more info
PubMed 
enables G protein-coupled receptor activity ISO
Inferred from Sequence Orthology
more info
 
enables G protein-coupled receptor activity ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
enables neuropeptide binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables peptide binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables prostaglandin D receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables prostaglandin D receptor activity IDA
Inferred from Direct Assay
more info
PubMed 
enables prostaglandin D receptor activity ISO
Inferred from Sequence Orthology
more info
 
enables prostaglandin F receptor activity IDA
Inferred from Direct Assay
more info
PubMed 
enables prostaglandin J receptor activity IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in integral component of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in integral component of plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in neuron projection IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
prostaglandin D2 receptor 2
Names
G-protein coupled receptor 44
PGD2 receptor
chemoattractant receptor-homologous molecule expressed on TH2 cells
prostaglandin D2 receptor CRTH2

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_009962.3NP_034092.1  prostaglandin D2 receptor 2

    See identical proteins and their annotated locations for NP_034092.1

    Status: VALIDATED

    Source sequence(s)
    AC132402, AC148991, AK041947
    Consensus CDS
    CCDS29592.1
    UniProtKB/Swiss-Prot
    Q9Z2J6
    Related
    ENSMUSP00000036159.4, ENSMUST00000037261.4
    Conserved Domains (2) summary
    cd14964
    Location:3458
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:32314
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000085.7 Reference GRCm39 C57BL/6J

    Range
    10901883..10919875
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011247148.4XP_011245450.1  prostaglandin D2 receptor 2 isoform X1

    See identical proteins and their annotated locations for XP_011245450.1

    UniProtKB/Swiss-Prot
    Q9Z2J6
    Conserved Domains (2) summary
    cd14964
    Location:3458
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:32314
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
  2. XM_006526695.5XP_006526758.1  prostaglandin D2 receptor 2 isoform X1

    See identical proteins and their annotated locations for XP_006526758.1

    UniProtKB/Swiss-Prot
    Q9Z2J6
    Conserved Domains (2) summary
    cd14964
    Location:3458
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:32314
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
  3. XM_006526696.5XP_006526759.1  prostaglandin D2 receptor 2 isoform X1

    See identical proteins and their annotated locations for XP_006526759.1

    UniProtKB/Swiss-Prot
    Q9Z2J6
    Conserved Domains (2) summary
    cd14964
    Location:3458
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:32314
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
Support Center