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Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) [ Mus musculus (house mouse) ]

Gene ID: 14810, updated on 28-Nov-2021

Summary

Official Symbol
Grin1provided by MGI
Official Full Name
glutamate receptor, ionotropic, NMDA1 (zeta 1)provided by MGI
Primary source
MGI:MGI:95819
See related
Ensembl:ENSMUSG00000026959
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
NR1; GluN1; Nmdar; NMD-R1; NMDAR1; M100174; Rgsc174; GluRzeta1; GluRdelta1
Expression
Biased expression in cortex adult (RPKM 73.7), frontal lobe adult (RPKM 72.0) and 5 other tissues See more
Orthologs
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Genomic context

See Grin1 in Genome Data Viewer
Location:
2 A3; 2 17.14 cM
Exon count:
21
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (25181189..25209199, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (25291177..25319187, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (25146697..25174683, complement)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene anaphase promoting complex subunit 2 Neighboring gene transmembrane protein 210 Neighboring gene leucine rich repeat containing 26 Neighboring gene glutamate receptor, ionotropic, NMDA1 (zeta 1), opposite strand Neighboring gene expressed sequence AA543186 Neighboring gene mannosidase, alpha, class 1B, member 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (26)  1 citation
  • Chemically induced (ENU) (1) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
contributes_to NMDA glutamate receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables NMDA glutamate receptor activity IDA
Inferred from Direct Assay
more info
PubMed 
enables NMDA glutamate receptor activity IGI
Inferred from Genetic Interaction
more info
PubMed 
enables NMDA glutamate receptor activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
contributes_to NMDA glutamate receptor activity ISO
Inferred from Sequence Orthology
more info
 
enables NMDA glutamate receptor activity ISO
Inferred from Sequence Orthology
more info
PubMed 
enables amyloid-beta binding ISO
Inferred from Sequence Orthology
more info
 
enables calcium channel activity IDA
Inferred from Direct Assay
more info
PubMed 
enables calcium channel activity IGI
Inferred from Genetic Interaction
more info
PubMed 
contributes_to calcium channel activity ISO
Inferred from Sequence Orthology
more info
 
enables calcium ion binding IDA
Inferred from Direct Assay
more info
PubMed 
enables calmodulin binding IDA
Inferred from Direct Assay
more info
PubMed 
enables cation channel activity IGI
Inferred from Genetic Interaction
more info
PubMed 
enables enzyme binding ISO
Inferred from Sequence Orthology
more info
 
enables glutamate binding ISO
Inferred from Sequence Orthology
more info
 
enables glutamate receptor binding ISO
Inferred from Sequence Orthology
more info
 
enables glutamate-gated calcium ion channel activity ISO
Inferred from Sequence Orthology
more info
 
enables glycine binding IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables glycine binding ISO
Inferred from Sequence Orthology
more info
 
enables ion channel activity IEA
Inferred from Electronic Annotation
more info
 
enables ionotropic glutamate receptor activity ISO
Inferred from Sequence Orthology
more info
 
enables ligand-gated ion channel activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables ligand-gated ion channel activity involved in regulation of presynaptic membrane potential ISO
Inferred from Sequence Orthology
more info
 
enables neurotransmitter binding ISO
Inferred from Sequence Orthology
more info
 
enables phosphatase binding ISO
Inferred from Sequence Orthology
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein-containing complex binding ISO
Inferred from Sequence Orthology
more info
 
enables signaling receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables signaling receptor binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables signaling receptor binding ISO
Inferred from Sequence Orthology
more info
 
enables transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential ISO
Inferred from Sequence Orthology
more info
 
enables voltage-gated cation channel activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within adult locomotory behavior IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within associative learning IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within calcium ion homeostasis IDA
Inferred from Direct Assay
more info
PubMed 
involved_in calcium ion transmembrane import into cytosol ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within calcium ion transport IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within calcium ion transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within cation transport IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in cation transport ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within cellular calcium ion homeostasis IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within cerebral cortex development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in chemical synaptic transmission IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within chemical synaptic transmission TAS
Traceable Author Statement
more info
PubMed 
acts_upstream_of_or_within conditioned taste aversion IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within excitatory postsynaptic potential IGI
Inferred from Genetic Interaction
more info
PubMed 
acts_upstream_of_or_within excitatory postsynaptic potential IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within ion transport IEA
Inferred from Electronic Annotation
more info
 
involved_in ion transport IEA
Inferred from Electronic Annotation
more info
 
involved_in ionotropic glutamate receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within ionotropic glutamate receptor signaling pathway IDA
Inferred from Direct Assay
more info
PubMed 
involved_in ionotropic glutamate receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within learning IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within learning or memory IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within long-term memory IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within male mating behavior IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within memory IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within negative regulation of neuron apoptotic process IGI
Inferred from Genetic Interaction
more info
PubMed 
acts_upstream_of_or_within negative regulation of neuron apoptotic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within neuromuscular process IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within olfactory learning IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within pons maturation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of Schwann cell migration ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within positive regulation of apoptotic process IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in positive regulation of calcium ion transport into cytosol ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of cell death ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of cysteine-type endopeptidase activity ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of dendritic spine maintenance ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of excitatory postsynaptic potential ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of reactive oxygen species biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within prepulse inhibition IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in propylene metabolic process IDA
Inferred from Direct Assay
more info
PubMed 
involved_in protein heterotetramerization ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within protein localization to postsynaptic membrane IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in protein-containing complex assembly ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within regulation of axonogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within regulation of cell communication IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within regulation of dendrite morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within regulation of long-term neuronal synaptic plasticity IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of membrane potential IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within regulation of membrane potential IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within regulation of membrane potential IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of membrane potential ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within regulation of neuron apoptotic process IGI
Inferred from Genetic Interaction
more info
PubMed 
acts_upstream_of_or_within regulation of neuron apoptotic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within regulation of neuronal synaptic plasticity IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within regulation of respiratory gaseous exchange IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within regulation of synapse assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within regulation of synaptic plasticity IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within response to amphetamine IGI
Inferred from Genetic Interaction
more info
PubMed 
acts_upstream_of_or_within response to amphetamine IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in response to ethanol ISO
Inferred from Sequence Orthology
more info
 
involved_in response to glycine ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within response to morphine IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in rhythmic process ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within sensory perception of pain IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within social behavior IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within startle response IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within suckling behavior IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within synaptic transmission, glutamatergic IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within visual learning IGI
Inferred from Genetic Interaction
more info
PubMed 
acts_upstream_of_or_within visual learning IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
part_of NMDA selective glutamate receptor complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of NMDA selective glutamate receptor complex IPI
Inferred from Physical Interaction
more info
PubMed 
part_of NMDA selective glutamate receptor complex ISO
Inferred from Sequence Orthology
more info
 
located_in cell junction IEA
Inferred from Electronic Annotation
more info
 
located_in cell surface IDA
Inferred from Direct Assay
more info
PubMed 
located_in cell surface IMP
Inferred from Mutant Phenotype
more info
PubMed 
located_in cell surface ISO
Inferred from Sequence Orthology
more info
 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in dendrite IDA
Inferred from Direct Assay
more info
PubMed 
located_in dendrite IMP
Inferred from Mutant Phenotype
more info
PubMed 
located_in dendrite ISO
Inferred from Sequence Orthology
more info
 
located_in dendrite membrane ISO
Inferred from Sequence Orthology
more info
 
located_in dendritic branch ISO
Inferred from Sequence Orthology
more info
 
located_in dendritic spine IDA
Inferred from Direct Assay
more info
PubMed 
located_in dendritic spine ISO
Inferred from Sequence Orthology
more info
 
located_in endoplasmic reticulum IDA
Inferred from Direct Assay
more info
PubMed 
located_in endoplasmic reticulum membrane TAS
Traceable Author Statement
more info
 
located_in excitatory synapse ISO
Inferred from Sequence Orthology
more info
 
is_active_in glutamatergic synapse IDA
Inferred from Direct Assay
more info
PubMed 
located_in growth cone NAS
Non-traceable Author Statement
more info
PubMed 
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in integral component of plasma membrane ISO
Inferred from Sequence Orthology
more info
 
is_active_in integral component of postsynaptic density membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in membrane IC
Inferred by Curator
more info
PubMed 
located_in membrane IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in neuron projection IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in neuronal cell body ISO
Inferred from Sequence Orthology
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 
located_in plasma membrane TAS
Traceable Author Statement
more info
 
located_in postsynaptic density IDA
Inferred from Direct Assay
more info
PubMed 
located_in postsynaptic density ISO
Inferred from Sequence Orthology
more info
 
located_in postsynaptic density membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in postsynaptic membrane IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in synapse IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in synapse IDA
Inferred from Direct Assay
more info
PubMed 
located_in synapse ISO
Inferred from Sequence Orthology
more info
PubMed 
located_in synaptic cleft ISO
Inferred from Sequence Orthology
more info
 
located_in synaptic membrane ISO
Inferred from Sequence Orthology
more info
 
located_in synaptic vesicle IDA
Inferred from Direct Assay
more info
PubMed 
located_in synaptic vesicle membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in terminal bouton ISO
Inferred from Sequence Orthology
more info
 
located_in transport vesicle membrane TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
glutamate receptor ionotropic, NMDA 1
Names
N-methyl-D-aspartate receptor subunit NR1
glutamate [NMDA] receptor subunit zeta-1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001177656.2NP_001171127.1  glutamate receptor ionotropic, NMDA 1 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) contains an additional in-frame exon in the 5' coding region, and lacks an exon and contains an alternate 3' terminal exon, resulting in an alternate 3' coding region, compared to variant 1. The encoded isoform (2) has distinct C-terminus and is shorter than isoform 1.
    Source sequence(s)
    AI844150, AK158175, BC039157, CD355382
    Consensus CDS
    CCDS50529.1
    UniProtKB/Swiss-Prot
    P35438
    UniProtKB/TrEMBL
    A2AI16
    Related
    ENSMUSP00000109956.4, ENSMUST00000114317.10
    Conserved Domains (5) summary
    cd06379
    Location:8404
    PBP1_iGluR_NMDA_NR1; N-terminal leucine/isoleucine/valine-binding protein (LIVBP)-like domain of the NR1, an essential channel-forming subunit of the NMDA receptor
    cd13719
    Location:416820
    PBP2_iGluR_NMDA_Nr1; The ligand-binding domain of the NR1 subunit of ionotropic NMDA (N-methyl-D-aspartate) glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
    pfam00060
    Location:582845
    Lig_chan; Ligand-gated ion channel
    pfam01094
    Location:42378
    ANF_receptor; Receptor family ligand binding region
    pfam10562
    Location:856884
    CaM_bdg_C0; Calmodulin-binding domain C0 of NMDA receptor NR1 subunit
  2. NM_001177657.2NP_001171128.1  glutamate receptor ionotropic, NMDA 1 isoform 3 precursor

    See identical proteins and their annotated locations for NP_001171128.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) lacks an exon and contains an alternate 3' terminal exon, resulting in an alternate 3' coding region, compared to variant 1. The encoded isoform (3) has distinct C-terminus and is shorter than isoform 1.
    Source sequence(s)
    AI844150, BC039157, CD355382
    Consensus CDS
    CCDS50528.1
    UniProtKB/Swiss-Prot
    P35438
    Related
    ENSMUSP00000109951.2, ENSMUST00000114312.2
    Conserved Domains (5) summary
    cd06379
    Location:8383
    PBP1_iGluR_NMDA_NR1; N-terminal leucine/isoleucine/valine-binding protein (LIVBP)-like domain of the NR1, an essential channel-forming subunit of the NMDA receptor
    cd13719
    Location:395799
    PBP2_iGluR_NMDA_Nr1; The ligand-binding domain of the NR1 subunit of ionotropic NMDA (N-methyl-D-aspartate) glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
    pfam00060
    Location:561824
    Lig_chan; Ligand-gated ion channel
    pfam01094
    Location:42357
    ANF_receptor; Receptor family ligand binding region
    pfam10562
    Location:835863
    CaM_bdg_C0; Calmodulin-binding domain C0 of NMDA receptor NR1 subunit
  3. NM_001372558.1NP_001359487.1  glutamate receptor ionotropic, NMDA 1 isoform 4 precursor

    Status: VALIDATED

    Source sequence(s)
    AL732309
    Consensus CDS
    CCDS89447.1
    Related
    ENSMUSP00000109949.4, ENSMUST00000114310.10
    Conserved Domains (4) summary
    cd13719
    Location:416820
    PBP2_iGluR_NMDA_Nr1; The ligand-binding domain of the NR1 subunit of ionotropic NMDA (N-methyl-D-aspartate) glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
    pfam07885
    Location:622677
    Ion_trans_2; Ion channel
    pfam10562
    Location:856884
    CaM_bdg_C0; Calmodulin-binding domain C0 of NMDA receptor NR1 subunit
    cd06379
    Location:25404
    PBP1_iGluR_NMDA_NR1; N-terminal leucine-isoleucine-valine-binding protein (LIVBP)-like domain of the NR1, an essential channel-forming subunit of the NMDA receptor
  4. NM_001372559.1NP_001359488.1  glutamate receptor ionotropic, NMDA 1 isoform 5 precursor

    Status: VALIDATED

    Source sequence(s)
    AL732309
    Consensus CDS
    CCDS89446.1
    Related
    ENSMUSP00000109957.4, ENSMUST00000114318.10
    Conserved Domains (4) summary
    cd13719
    Location:416820
    PBP2_iGluR_NMDA_Nr1; The ligand-binding domain of the NR1 subunit of ionotropic NMDA (N-methyl-D-aspartate) glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
    pfam07885
    Location:622677
    Ion_trans_2; Ion channel
    pfam10562
    Location:856884
    CaM_bdg_C0; Calmodulin-binding domain C0 of NMDA receptor NR1 subunit
    cd06379
    Location:25404
    PBP1_iGluR_NMDA_NR1; N-terminal leucine-isoleucine-valine-binding protein (LIVBP)-like domain of the NR1, an essential channel-forming subunit of the NMDA receptor
  5. NM_001372560.1NP_001359489.1  glutamate receptor ionotropic, NMDA 1 isoform 6 precursor

    Status: VALIDATED

    Source sequence(s)
    AL732309
    Consensus CDS
    CCDS89445.1
    Related
    ENSMUSP00000109947.4, ENSMUST00000114308.10
    Conserved Domains (4) summary
    cd13719
    Location:416820
    PBP2_iGluR_NMDA_Nr1; The ligand-binding domain of the NR1 subunit of ionotropic NMDA (N-methyl-D-aspartate) glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
    pfam07885
    Location:622677
    Ion_trans_2; Ion channel
    pfam10562
    Location:856884
    CaM_bdg_C0; Calmodulin-binding domain C0 of NMDA receptor NR1 subunit
    cd06379
    Location:25404
    PBP1_iGluR_NMDA_NR1; N-terminal leucine-isoleucine-valine-binding protein (LIVBP)-like domain of the NR1, an essential channel-forming subunit of the NMDA receptor
  6. NM_001372561.1NP_001359490.1  glutamate receptor ionotropic, NMDA 1 isoform 7 precursor

    Status: VALIDATED

    Source sequence(s)
    AL732309
    Consensus CDS
    CCDS89444.1
    Related
    ENSMUSP00000109953.4, ENSMUST00000114314.10
    Conserved Domains (4) summary
    cd13719
    Location:395799
    PBP2_iGluR_NMDA_Nr1; The ligand-binding domain of the NR1 subunit of ionotropic NMDA (N-methyl-D-aspartate) glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
    pfam07885
    Location:601656
    Ion_trans_2; Ion channel
    pfam10562
    Location:835863
    CaM_bdg_C0; Calmodulin-binding domain C0 of NMDA receptor NR1 subunit
    cd06379
    Location:25383
    PBP1_iGluR_NMDA_NR1; N-terminal leucine-isoleucine-valine-binding protein (LIVBP)-like domain of the NR1, an essential channel-forming subunit of the NMDA receptor
  7. NM_001372562.1NP_001359491.1  glutamate receptor ionotropic, NMDA 1 isoform 8 precursor

    Status: VALIDATED

    Source sequence(s)
    AL732309
    Consensus CDS
    CCDS89443.1
    Related
    ENSMUSP00000109946.2, ENSMUST00000114307.8
    Conserved Domains (4) summary
    cd13719
    Location:395799
    PBP2_iGluR_NMDA_Nr1; The ligand-binding domain of the NR1 subunit of ionotropic NMDA (N-methyl-D-aspartate) glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
    pfam07885
    Location:601656
    Ion_trans_2; Ion channel
    pfam10562
    Location:835863
    CaM_bdg_C0; Calmodulin-binding domain C0 of NMDA receptor NR1 subunit
    cd06379
    Location:25383
    PBP1_iGluR_NMDA_NR1; N-terminal leucine-isoleucine-valine-binding protein (LIVBP)-like domain of the NR1, an essential channel-forming subunit of the NMDA receptor
  8. NM_008169.3NP_032195.1  glutamate receptor ionotropic, NMDA 1 isoform 1 precursor

    See identical proteins and their annotated locations for NP_032195.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes isoform (1).
    Source sequence(s)
    AI844150, AW494928, BC039157, CD355382, CD363997
    Consensus CDS
    CCDS15764.1
    UniProtKB/Swiss-Prot
    P35438
    Related
    ENSMUSP00000028335.7, ENSMUST00000028335.13
    Conserved Domains (6) summary
    cd06379
    Location:8383
    PBP1_iGluR_NMDA_NR1; N-terminal leucine/isoleucine/valine-binding protein (LIVBP)-like domain of the NR1, an essential channel-forming subunit of the NMDA receptor
    cd13719
    Location:395799
    PBP2_iGluR_NMDA_Nr1; The ligand-binding domain of the NR1 subunit of ionotropic NMDA (N-methyl-D-aspartate) glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
    pfam00060
    Location:561824
    Lig_chan; Ligand-gated ion channel
    pfam01094
    Location:42357
    ANF_receptor; Receptor family ligand binding region
    pfam07885
    Location:602656
    Ion_trans_2; Ion channel
    pfam10562
    Location:835863
    CaM_bdg_C0; Calmodulin-binding domain C0 of NMDA receptor NR1 subunit

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    25181189..25209199 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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