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CTVgp01 401-kDa viral polyprotein [ Citrus tristeza virus ]

Gene ID: 1493986, updated on 15-Aug-2018

Summary

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Gene symbol
CTVgp01
Gene description
401-kDa viral polyprotein
Locus tag
CTVgp01
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Citrus tristeza virus
Lineage
Viruses; ssRNA viruses; ssRNA positive-strand viruses, no DNA stage; Closteroviridae; Closterovirus
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Genomic context

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Sequence:
NC_001661.1 (108..10857)

NC_001661.1Genomic Context describing neighboring genes Neighboring gene 33-kDa protein Neighboring gene 6-kDa protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001661.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The RNA-dependent RNA polymerase of Citrus tristeza virus forms oligomers. Cevik B. Virology, 2013 Dec. PMID 24210106
  2. In vivo and in vitro expression analysis of the RNA-dependent RNA polymerase of Citrus tristeza virus. Cevik B, et al. Arch Virol, 2008. PMID 18193157
  3. Screening of the closterovirus genome by degenerate primer-mediated polymerase chain reaction. Karasev AV, et al. J Gen Virol, 1994 Jun. PMID 8207405
  4. Transcriptional strategy of closteroviruses: mapping the 5' termini of the citrus tristeza virus subgenomic RNAs. Karasev AV, et al. J Virol, 1997 Aug. PMID 9223524, Free PMC Article
  5. Complete sequence of the citrus tristeza virus RNA genome. Karasev AV, et al. Virology, 1995 Apr 20. PMID 7747424

GeneRIFs: Gene References Into Functions

General protein information

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Preferred Names
401-kDa viral polyprotein
Names
papain-like protease
papain-like protease
replicase
NP_042860.2
  • p401; The CTV polyprotein contains domains for (5' to 3') two papain-like leader proteases, a methyltransferase, a helicase and a RNA-dependent RNA polymerase, identified by sequence comparisons

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001661.1 Reference assembly

    Range
    108..10857
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_042860.2 401-kDa viral polyprotein [Citrus tristeza virus]

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    Q66237
    Conserved Domains (7) summary
    pfam05533
    Location:891 → 977
    Peptidase_C42; Beet yellows virus-type papain-like endopeptidase C42
    pfam12267
    Location:646 → 812
    DUF3614; Protein of unknown function (DUF3614)
    pfam12364
    Location:1 → 131
    DUF3648; Protein of unknown function (DUF3648)
    pfam12591
    Location:211 → 289
    DUF3762; Protein of unknown function (DUF3762)
    pfam00978
    Location:3101 → 3515
    RdRP_2; RNA dependent RNA polymerase
    pfam01443
    Location:2716 → 2984
    Viral_helicase1; Viral (Superfamily 1) RNA helicase
    pfam01660
    Location:1036 → 1370
    Vmethyltransf; Viral methyltransferase

  2. NP_757347.1 papain-like protease

    Conserved Domains (3) summary
    pfam05533
    Location:396 → 480
    Peptidase_C42; Beet yellows virus-type papain-like endopeptidase C42
    pfam12364
    Location:1 → 131
    DUF3648; Protein of unknown function (DUF3648)
    pfam12591
    Location:211 → 289
    DUF3762; Protein of unknown function (DUF3762)

  3. NP_757348.1 papain-like protease

    Conserved Domains (2) summary
    pfam05533
    Location:407 → 488
    Peptidase_C42; Beet yellows virus-type papain-like endopeptidase C42
    pfam12267
    Location:162 → 328
    DUF3614; Protein of unknown function (DUF3614)

  4. NP_733947.1 replicase

    Conserved Domains (3) summary
    pfam00978
    Location:2125 → 2539
    RdRP_2; RNA dependent RNA polymerase
    pfam01443
    Location:1740 → 2008
    Viral_helicase1; Viral (Superfamily 1) RNA helicase
    pfam01660
    Location:60 → 394
    Vmethyltransf; Viral methyltransferase
Nucleotide Protein
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