Format

Send to:

Choose Destination

Hpca hippocalcin [ Mus musculus (house mouse) ]

Gene ID: 15444, updated on 23-Jun-2021

Summary

Official Symbol
Hpcaprovided by MGI
Official Full Name
hippocalcinprovided by MGI
Primary source
MGI:MGI:1336200
See related
Ensembl:ENSMUSG00000028785
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Expression
Biased expression in cortex adult (RPKM 184.5), frontal lobe adult (RPKM 103.2) and 3 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Hpca in Genome Data Viewer
Location:
4; 4 D2.2
Exon count:
9
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (129005363..129019712, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (129111570..129125919, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (128788819..128798984, complement)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene adenylate kinase 2 Neighboring gene RIKEN cDNA 1700086P04 gene Neighboring gene ring finger protein 19B Neighboring gene transmembrane protein 54 Neighboring gene fibronectin type III domain containing 5 Neighboring gene S100P binding protein

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1)  1 citation
  • Endonuclease-mediated (2) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables actin binding ISO
Inferred from Sequence Orthology
more info
 
enables calcium ion binding ISO
Inferred from Sequence Orthology
more info
 
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
 
enables kinase binding ISO
Inferred from Sequence Orthology
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in axon ISO
Inferred from Sequence Orthology
more info
 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in dendrite cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in dendrite membrane ISO
Inferred from Sequence Orthology
more info
 
located_in dendritic spine head ISO
Inferred from Sequence Orthology
more info
 
located_in extrinsic component of membrane ISO
Inferred from Sequence Orthology
more info
 
located_in glutamatergic synapse ISO
Inferred from Sequence Orthology
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in neuronal cell body membrane ISO
Inferred from Sequence Orthology
more info
 
located_in perikaryon ISO
Inferred from Sequence Orthology
more info
 
located_in postsynapse ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
neuron-specific calcium-binding protein hippocalcin

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001130419.2NP_001123891.1  neuron-specific calcium-binding protein hippocalcin

    See identical proteins and their annotated locations for NP_001123891.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2, 3 and 4 encode the same protein.
    Source sequence(s)
    AI835374, BC058588, BY128037, BY769297, CX240757
    Consensus CDS
    CCDS18682.1
    UniProtKB/Swiss-Prot
    P84075
    Related
    ENSMUSP00000129548.2, ENSMUST00000164649.8
    Conserved Domains (1) summary
    COG5126
    Location:13179
    FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]
  2. NM_001286081.1NP_001273010.1  neuron-specific calcium-binding protein hippocalcin

    See identical proteins and their annotated locations for NP_001273010.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2, 3 and 4 encode the same protein.
    Source sequence(s)
    AI835374, BC058588, CX238650, CX239660
    Consensus CDS
    CCDS18682.1
    UniProtKB/Swiss-Prot
    P84075
    Related
    ENSMUSP00000119178.3, ENSMUST00000139450.8
    Conserved Domains (1) summary
    COG5126
    Location:13179
    FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]
  3. NM_001286083.1NP_001273012.1  neuron-specific calcium-binding protein hippocalcin

    See identical proteins and their annotated locations for NP_001273012.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 1. Variants 1, 2, 3 and 4 encode the same protein.
    Source sequence(s)
    AI835374, BC058588, CX240088
    Consensus CDS
    CCDS18682.1
    UniProtKB/Swiss-Prot
    P84075
    Related
    ENSMUSP00000112143.3, ENSMUST00000116442.9
    Conserved Domains (1) summary
    COG5126
    Location:13179
    FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]
  4. NM_010471.4NP_034601.1  neuron-specific calcium-binding protein hippocalcin

    See identical proteins and their annotated locations for NP_034601.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1, 2, 3 and 4 encode the same protein.
    Source sequence(s)
    AI835374, AK002992, BC058588, BY129411
    Consensus CDS
    CCDS18682.1
    UniProtKB/Swiss-Prot
    P84075
    Related
    ENSMUSP00000030572.4, ENSMUST00000030572.10
    Conserved Domains (1) summary
    COG5126
    Location:13179
    FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    129005363..129019712 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030253224.1XP_030109084.1  neuron-specific calcium-binding protein hippocalcin isoform X1

    Conserved Domains (1) summary
    COG5126
    Location:13179
    FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]
  2. XM_030253226.1XP_030109086.1  neuron-specific calcium-binding protein hippocalcin isoform X1

    Conserved Domains (1) summary
    COG5126
    Location:13179
    FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]
  3. XM_030253227.1XP_030109087.1  neuron-specific calcium-binding protein hippocalcin isoform X1

    Conserved Domains (1) summary
    COG5126
    Location:13179
    FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]
  4. XM_006502776.5XP_006502839.1  neuron-specific calcium-binding protein hippocalcin isoform X1

    See identical proteins and their annotated locations for XP_006502839.1

    UniProtKB/Swiss-Prot
    P84075
    Conserved Domains (1) summary
    COG5126
    Location:13179
    FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]
  5. XM_006502775.4XP_006502838.1  neuron-specific calcium-binding protein hippocalcin isoform X1

    See identical proteins and their annotated locations for XP_006502838.1

    UniProtKB/Swiss-Prot
    P84075
    Related
    ENSMUSP00000112145.3, ENSMUST00000116444.10
    Conserved Domains (1) summary
    COG5126
    Location:13179
    FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]
  6. XM_030253225.1XP_030109085.1  neuron-specific calcium-binding protein hippocalcin isoform X1

    Conserved Domains (1) summary
    COG5126
    Location:13179
    FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]
  7. XM_006502777.3XP_006502840.1  neuron-specific calcium-binding protein hippocalcin isoform X1

    See identical proteins and their annotated locations for XP_006502840.1

    UniProtKB/Swiss-Prot
    P84075
    Conserved Domains (1) summary
    COG5126
    Location:13179
    FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]
Support Center