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Htr1d 5-hydroxytryptamine (serotonin) receptor 1D [ Mus musculus (house mouse) ]

Gene ID: 15552, updated on 16-Oct-2021

Summary

Official Symbol
Htr1dprovided by MGI
Official Full Name
5-hydroxytryptamine (serotonin) receptor 1Dprovided by MGI
Primary source
MGI:MGI:96276
See related
Ensembl:ENSMUSG00000070687
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
5-HT1D; Gpcr14; Htr1db; 5-HT-1D; AI853647
Expression
Biased expression in ovary adult (RPKM 1.0), bladder adult (RPKM 0.8) and 12 other tissues See more
Orthologs
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Genomic context

See Htr1d in Genome Data Viewer
Location:
4 D3; 4 68.74 cM
Exon count:
5
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (136150829..136176284)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (136423522..136444405)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (135979439..136000317)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene heterogeneous nuclear ribonucleoprotein R Neighboring gene predicted gene, 54262 Neighboring gene predicted gene, 31295 Neighboring gene leucine zipper protein 1 Neighboring gene lysine (K)-specific demethylase 1A Neighboring gene heterogeneous nuclear ribonucleoprotein A3 pseudogene Neighboring gene testis expressed 46

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (3) 

Pathways from PubChem

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables G protein-coupled serotonin receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables G protein-coupled serotonin receptor activity IDA
Inferred from Direct Assay
more info
PubMed 
enables G protein-coupled serotonin receptor activity ISO
Inferred from Sequence Orthology
more info
 
enables neurotransmitter receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables serotonin binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables serotonin binding IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
is_active_in dendrite IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in integral component of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in integral component of plasma membrane ISO
Inferred from Sequence Orthology
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
5-hydroxytryptamine receptor 1D
Names
5-hydroxytryptamine (serotonin) receptor 1D beta
G-protein coupled receptor 14
serotonin receptor 1D

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001285482.1NP_001272411.1  5-hydroxytryptamine receptor 1D

    See identical proteins and their annotated locations for NP_001272411.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2, 3 and 4 all encode the same protein.
    Source sequence(s)
    AI853647, AK082016, AL670673, AW487918, BY728591
    Consensus CDS
    CCDS18806.1
    UniProtKB/Swiss-Prot
    Q61224
    Related
    ENSMUSP00000112402.2, ENSMUST00000121571.8
    Conserved Domains (2) summary
    cd14964
    Location:3862
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:32364
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
  2. NM_001285483.1NP_001272412.1  5-hydroxytryptamine receptor 1D

    See identical proteins and their annotated locations for NP_001272412.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1, 2, 3 and 4 all encode the same protein.
    Source sequence(s)
    AI853647, AK082016, AL670673, AW487918
    Consensus CDS
    CCDS18806.1
    UniProtKB/Swiss-Prot
    Q61224
    Related
    ENSMUSP00000112840.2, ENSMUST00000117699.2
    Conserved Domains (2) summary
    cd14964
    Location:3862
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:32364
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
  3. NM_001285484.1NP_001272413.1  5-hydroxytryptamine receptor 1D

    See identical proteins and their annotated locations for NP_001272413.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 1. Variants 1, 2, 3 and 4 all encode the same protein.
    Source sequence(s)
    AI853647, AK082016, AL670673, AW487918
    Consensus CDS
    CCDS18806.1
    UniProtKB/Swiss-Prot
    Q61224
    Conserved Domains (2) summary
    cd14964
    Location:3862
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:32364
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
  4. NM_008309.5NP_032335.2  5-hydroxytryptamine receptor 1D

    See identical proteins and their annotated locations for NP_032335.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2, 3 and 4 all encode the same protein.
    Source sequence(s)
    AI853647, AK082016, AW487918, BY728591
    Consensus CDS
    CCDS18806.1
    UniProtKB/Swiss-Prot
    Q61224
    Related
    ENSMUSP00000086052.5, ENSMUST00000088677.5
    Conserved Domains (2) summary
    cd14964
    Location:3862
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:32364
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    136150829..136176284
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006538578.3XP_006538641.1  5-hydroxytryptamine receptor 1D isoform X1

    See identical proteins and their annotated locations for XP_006538641.1

    UniProtKB/Swiss-Prot
    Q61224
    Conserved Domains (2) summary
    cd14964
    Location:3862
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:32364
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
  2. XM_017319986.3XP_017175475.1  5-hydroxytryptamine receptor 1D isoform X1

    UniProtKB/Swiss-Prot
    Q61224
    Conserved Domains (2) summary
    cd14964
    Location:3862
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:32364
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
  3. XM_006538577.4XP_006538640.1  5-hydroxytryptamine receptor 1D isoform X1

    See identical proteins and their annotated locations for XP_006538640.1

    UniProtKB/Swiss-Prot
    Q61224
    Conserved Domains (2) summary
    cd14964
    Location:3862
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:32364
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
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