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Elavl2 ELAV like RNA binding protein 1 [ Mus musculus (house mouse) ]

Gene ID: 15569, updated on 25-Nov-2021

Summary

Official Symbol
Elavl2provided by MGI
Official Full Name
ELAV like RNA binding protein 1provided by MGI
Primary source
MGI:MGI:1100887
See related
Ensembl:ENSMUSG00000008489
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Hub; mel-N1
Expression
Biased expression in whole brain E14.5 (RPKM 12.9), CNS E18 (RPKM 11.4) and 5 other tissues See more
Orthologs
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Genomic context

See Elavl2 in Genome Data Viewer
Location:
4 C5; 4 42.36 cM
Exon count:
17
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (91099770..91288407, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (91211533..91400108, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (90917457..91066675, complement)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene predicted gene 12643 Neighboring gene within bgcn homolog pseudogene Neighboring gene non-metastatic cells 6, protein expressed in (nucleoside-diphosphate kinase) pseudogene Neighboring gene microRNA 6402 Neighboring gene predicted gene, 40202 Neighboring gene heat shock protein 1 (chaperonin) pseudogene 21

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 
  • Targeted (2)  1 citation
  • Endonuclease-mediated (1) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within cellular response to leukemia inhibitory factor IEP
Inferred from Expression Pattern
more info
PubMed 
Component Evidence Code Pubs
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
 
is_active_in synapse EXP
Inferred from Experiment
more info
PubMed 
is_active_in synapse IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
ELAV-like protein 2
Names
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
ELAV-like neuronal protein 1
HU-antigen B
nervous system-specific RNA-binding protein Mel-N1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001177883.2NP_001171354.1  ELAV-like protein 2 isoform 4

    See identical proteins and their annotated locations for NP_001171354.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) lacks an alterntae exon in the 5' end, which causes translation initiation at a downstream start codon, compared to variant 5. The resulting isoform (4) has a shorter N-terminus when it is compared to isoform 5.
    Source sequence(s)
    AK141919, AL954140, BC046598, BY284852, CO038990
    Consensus CDS
    CCDS51230.1
    UniProtKB/TrEMBL
    Q3UR02
    Related
    ENSMUSP00000102741.4, ENSMUST00000107124.10
    Conserved Domains (1) summary
    TIGR01661
    Location:36358
    ELAV_HUD_SF; ELAV/HuD family splicing factor
  2. NM_001347149.2NP_001334078.1  ELAV-like protein 2 isoform 5

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) encodes isoform 5.
    Source sequence(s)
    AL837505, AL954140, BY284852, CO038990
    Consensus CDS
    CCDS84753.1
    UniProtKB/TrEMBL
    B1AXZ4
    Related
    ENSMUSP00000102737.2, ENSMUST00000107120.8
    Conserved Domains (1) summary
    TIGR01661
    Location:65387
    ELAV_HUD_SF; ELAV/HuD family splicing factor
  3. NM_001357188.1NP_001344117.1  ELAV-like protein 2 isoform 6

    Status: VALIDATED

    Source sequence(s)
    AK141919, AL954140, BC046598, BI985114, BY284852, CB524847, CO038990
    Consensus CDS
    CCDS89779.1
    Conserved Domains (1) summary
    TIGR01661
    Location:65388
    ELAV_HUD_SF; ELAV/HuD family splicing factor
  4. NM_001357189.1NP_001344118.1  ELAV-like protein 2 isoform 6

    Status: VALIDATED

    Source sequence(s)
    AK141919, AL954140, BC046598, BI985114, BY129136, CB524847, CO038990
    Consensus CDS
    CCDS89779.1
    Related
    ENSMUSP00000102733.3, ENSMUST00000107116.9
    Conserved Domains (1) summary
    TIGR01661
    Location:65388
    ELAV_HUD_SF; ELAV/HuD family splicing factor
  5. NM_001374236.1NP_001361165.1  ELAV-like protein 2 isoform 5

    Status: VALIDATED

    Source sequence(s)
    AL837505, AL954140
    Conserved Domains (1) summary
    TIGR01661
    Location:65387
    ELAV_HUD_SF; ELAV/HuD family splicing factor
  6. NM_001374237.1NP_001361166.1  ELAV-like protein 2 isoform 5

    Status: VALIDATED

    Source sequence(s)
    AL837505, AL954140
    Consensus CDS
    CCDS84753.1
    Conserved Domains (1) summary
    TIGR01661
    Location:65387
    ELAV_HUD_SF; ELAV/HuD family splicing factor
  7. NM_001374238.1NP_001361167.1  ELAV-like protein 2 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AL837505, AL954140
    Consensus CDS
    CCDS51230.1
    Conserved Domains (1) summary
    TIGR01661
    Location:36358
    ELAV_HUD_SF; ELAV/HuD family splicing factor
  8. NM_001374696.1NP_001361625.1  ELAV-like protein 2 isoform 7

    Status: VALIDATED

    Source sequence(s)
    AL837505, AL954140
    Consensus CDS
    CCDS89778.1
    Related
    ENSMUSP00000102735.2, ENSMUST00000107118.8
    Conserved Domains (1) summary
    TIGR01661
    Location:65375
    ELAV_HUD_SF; ELAV/HuD family splicing factor
  9. NM_010486.2NP_034616.1  ELAV-like protein 2 isoform 2

    See identical proteins and their annotated locations for NP_034616.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) has multiple differences, one of which causes translation initiation at a downstream start codon, compared to variant 5. The resulting isoform (2) has a shorter N-terminus and has one additional aa in the C-terminus when it is compared to isoform 5.
    Source sequence(s)
    BC046598, BY129136, U29088
    Consensus CDS
    CCDS18355.1
    UniProtKB/Swiss-Prot
    Q60899
    UniProtKB/TrEMBL
    Q564D8, Q80UJ0
    Related
    ENSMUSP00000008633.9, ENSMUST00000008633.15
    Conserved Domains (1) summary
    TIGR01661
    Location:36359
    ELAV_HUD_SF; ELAV/HuD family splicing factor
  10. NM_207685.2NP_997568.1  ELAV-like protein 2 isoform 1

    See identical proteins and their annotated locations for NP_997568.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) differs in the 5' UTR and coding sequence compared to variant 5. The resulting isoform (1) has a shorter and distinct N-terminus compared to isoform 5.
    Source sequence(s)
    AL954140, BC046598, BC058393, CO038990
    Consensus CDS
    CCDS18354.1
    UniProtKB/TrEMBL
    Q80Y51
    Related
    ENSMUSP00000099863.4, ENSMUST00000102799.10
    Conserved Domains (1) summary
    TIGR01661
    Location:50372
    ELAV_HUD_SF; ELAV/HuD family splicing factor
  11. NM_207686.1NP_997569.1  ELAV-like protein 2 isoform 3

    See identical proteins and their annotated locations for NP_997569.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) has multiple differences, one of which causes translation initiation at a downstream start codon, compared to variant 5. The resulting isoform (3) has a shorter N-terminus and has one additional aa in the C-terminus when it is compared to isoform 5.
    Source sequence(s)
    BC046598, BY129136
    Consensus CDS
    CCDS18356.1
    UniProtKB/TrEMBL
    Q80UJ0
    Related
    ENSMUSP00000102727.2, ENSMUST00000107110.8
    Conserved Domains (1) summary
    TIGR01661
    Location:36346
    ELAV_HUD_SF; ELAV/HuD family splicing factor

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    91099770..91288407 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036163717.1XP_036019610.1  ELAV-like protein 2 isoform X12

    Conserved Domains (1) summary
    TIGR01661
    Location:50372
    ELAV_HUD_SF; ELAV/HuD family splicing factor
  2. XM_036163715.1XP_036019608.1  ELAV-like protein 2 isoform X8

    Conserved Domains (1) summary
    TIGR01661
    Location:65387
    ELAV_HUD_SF; ELAV/HuD family splicing factor
  3. XM_006502784.5XP_006502847.1  ELAV-like protein 2 isoform X7

    See identical proteins and their annotated locations for XP_006502847.1

    UniProtKB/TrEMBL
    B1AXZ5
    Conserved Domains (1) summary
    TIGR01661
    Location:65388
    ELAV_HUD_SF; ELAV/HuD family splicing factor
  4. XM_006502788.5XP_006502851.1  ELAV-like protein 2 isoform X13

    Conserved Domains (1) summary
    TIGR01661
    Location:49372
    ELAV_HUD_SF; ELAV/HuD family splicing factor
  5. XM_006502787.5XP_006502850.1  ELAV-like protein 2 isoform X11

    See identical proteins and their annotated locations for XP_006502850.1

    Conserved Domains (1) summary
    TIGR01661
    Location:50373
    ELAV_HUD_SF; ELAV/HuD family splicing factor
  6. XM_030253232.2XP_030109092.1  ELAV-like protein 2 isoform X7

    Conserved Domains (1) summary
    TIGR01661
    Location:65388
    ELAV_HUD_SF; ELAV/HuD family splicing factor
  7. XM_036163714.1XP_036019607.1  ELAV-like protein 2 isoform X8

    Conserved Domains (1) summary
    TIGR01661
    Location:65387
    ELAV_HUD_SF; ELAV/HuD family splicing factor
  8. XM_036163713.1XP_036019606.1  ELAV-like protein 2 isoform X7

    Conserved Domains (1) summary
    TIGR01661
    Location:65388
    ELAV_HUD_SF; ELAV/HuD family splicing factor
  9. XM_036163727.1XP_036019620.1  ELAV-like protein 2 isoform X17

    Related
    ENSMUSP00000102728.3, ENSMUST00000107111.9
    Conserved Domains (1) summary
    TIGR01661
    Location:36345
    ELAV_HUD_SF; ELAV/HuD family splicing factor
  10. XM_036163725.1XP_036019618.1  ELAV-like protein 2 isoform X16

    Conserved Domains (1) summary
    TIGR01661
    Location:36346
    ELAV_HUD_SF; ELAV/HuD family splicing factor
  11. XM_036163722.1XP_036019615.1  ELAV-like protein 2 isoform X15

    Conserved Domains (1) summary
    TIGR01661
    Location:36358
    ELAV_HUD_SF; ELAV/HuD family splicing factor
  12. XM_036163718.1XP_036019611.1  ELAV-like protein 2 isoform X14

    Conserved Domains (1) summary
    TIGR01661
    Location:36359
    ELAV_HUD_SF; ELAV/HuD family splicing factor
  13. XM_036163716.1XP_036019609.1  ELAV-like protein 2 isoform X10

    Conserved Domains (1) summary
    TIGR01661
    Location:65375
    ELAV_HUD_SF; ELAV/HuD family splicing factor
  14. XM_030253243.2XP_030109103.1  ELAV-like protein 2 isoform X16

    Conserved Domains (1) summary
    TIGR01661
    Location:36346
    ELAV_HUD_SF; ELAV/HuD family splicing factor
  15. XM_030253239.2XP_030109099.1  ELAV-like protein 2 isoform X15

    Conserved Domains (1) summary
    TIGR01661
    Location:36358
    ELAV_HUD_SF; ELAV/HuD family splicing factor
  16. XM_006502790.4XP_006502853.1  ELAV-like protein 2 isoform X14

    See identical proteins and their annotated locations for XP_006502853.1

    UniProtKB/Swiss-Prot
    Q60899
    UniProtKB/TrEMBL
    Q564D8
    Conserved Domains (1) summary
    TIGR01661
    Location:36359
    ELAV_HUD_SF; ELAV/HuD family splicing factor
  17. XM_017319989.3XP_017175478.1  ELAV-like protein 2 isoform X9

    Conserved Domains (1) summary
    TIGR01661
    Location:64387
    ELAV_HUD_SF; ELAV/HuD family splicing factor
  18. XM_030253233.2XP_030109093.1  ELAV-like protein 2 isoform X7

    Conserved Domains (1) summary
    TIGR01661
    Location:65388
    ELAV_HUD_SF; ELAV/HuD family splicing factor
  19. XM_006502785.5XP_006502848.1  ELAV-like protein 2 isoform X7

    See identical proteins and their annotated locations for XP_006502848.1

    UniProtKB/TrEMBL
    B1AXZ5
    Conserved Domains (1) summary
    TIGR01661
    Location:65388
    ELAV_HUD_SF; ELAV/HuD family splicing factor
  20. XM_036163721.1XP_036019614.1  ELAV-like protein 2 isoform X14

    Conserved Domains (1) summary
    TIGR01661
    Location:36359
    ELAV_HUD_SF; ELAV/HuD family splicing factor
  21. XM_030253236.2XP_030109096.1  ELAV-like protein 2 isoform X8

    Conserved Domains (1) summary
    TIGR01661
    Location:65387
    ELAV_HUD_SF; ELAV/HuD family splicing factor
  22. XM_036163724.1XP_036019617.1  ELAV-like protein 2 isoform X15

    Conserved Domains (1) summary
    TIGR01661
    Location:36358
    ELAV_HUD_SF; ELAV/HuD family splicing factor
  23. XM_036163729.1XP_036019622.1  ELAV-like protein 2 isoform X18

    Conserved Domains (1) summary
    TIGR01661
    Location:206335
    ELAV_HUD_SF; ELAV/HuD family splicing factor
  24. XM_036163728.1XP_036019621.1  ELAV-like protein 2 isoform X18

    Conserved Domains (1) summary
    TIGR01661
    Location:206335
    ELAV_HUD_SF; ELAV/HuD family splicing factor
  25. XM_006502779.5XP_006502842.1  ELAV-like protein 2 isoform X3

    Conserved Domains (1) summary
    TIGR01661
    Location:205528
    ELAV_HUD_SF; ELAV/HuD family splicing factor
  26. XM_036163711.1XP_036019604.1  ELAV-like protein 2 isoform X5

    Conserved Domains (1) summary
    TIGR01661
    Location:206516
    ELAV_HUD_SF; ELAV/HuD family splicing factor
  27. XM_036163712.1XP_036019605.1  ELAV-like protein 2 isoform X6

    Conserved Domains (1) summary
    TIGR01661
    Location:206515
    ELAV_HUD_SF; ELAV/HuD family splicing factor
  28. XM_036163726.1XP_036019619.1  ELAV-like protein 2 isoform X16

    Conserved Domains (1) summary
    TIGR01661
    Location:36346
    ELAV_HUD_SF; ELAV/HuD family splicing factor
  29. XM_030253231.2XP_030109091.1  ELAV-like protein 2 isoform X4

    Conserved Domains (1) summary
    TIGR01661
    Location:205527
    ELAV_HUD_SF; ELAV/HuD family splicing factor
  30. XM_036163709.1XP_036019602.1  ELAV-like protein 2 isoform X1

    Conserved Domains (1) summary
    TIGR01661
    Location:206529
    ELAV_HUD_SF; ELAV/HuD family splicing factor
  31. XM_036163708.1XP_036019601.1  ELAV-like protein 2 isoform X1

    Conserved Domains (1) summary
    TIGR01661
    Location:206529
    ELAV_HUD_SF; ELAV/HuD family splicing factor
  32. XM_036163704.1XP_036019597.1  ELAV-like protein 2 isoform X1

    Conserved Domains (1) summary
    TIGR01661
    Location:206529
    ELAV_HUD_SF; ELAV/HuD family splicing factor
  33. XM_036163706.1XP_036019599.1  ELAV-like protein 2 isoform X1

    Conserved Domains (1) summary
    TIGR01661
    Location:206529
    ELAV_HUD_SF; ELAV/HuD family splicing factor
  34. XM_036163707.1XP_036019600.1  ELAV-like protein 2 isoform X1

    Conserved Domains (1) summary
    TIGR01661
    Location:206529
    ELAV_HUD_SF; ELAV/HuD family splicing factor
  35. XM_036163703.1XP_036019596.1  ELAV-like protein 2 isoform X1

    Conserved Domains (1) summary
    TIGR01661
    Location:206529
    ELAV_HUD_SF; ELAV/HuD family splicing factor
  36. XM_036163700.1XP_036019593.1  ELAV-like protein 2 isoform X1

    Conserved Domains (1) summary
    TIGR01661
    Location:206529
    ELAV_HUD_SF; ELAV/HuD family splicing factor
  37. XM_036163705.1XP_036019598.1  ELAV-like protein 2 isoform X1

    Conserved Domains (1) summary
    TIGR01661
    Location:206529
    ELAV_HUD_SF; ELAV/HuD family splicing factor
  38. XM_036163702.1XP_036019595.1  ELAV-like protein 2 isoform X1

    Conserved Domains (1) summary
    TIGR01661
    Location:206529
    ELAV_HUD_SF; ELAV/HuD family splicing factor
  39. XM_036163699.1XP_036019592.1  ELAV-like protein 2 isoform X1

    Conserved Domains (1) summary
    TIGR01661
    Location:206529
    ELAV_HUD_SF; ELAV/HuD family splicing factor
  40. XM_036163701.1XP_036019594.1  ELAV-like protein 2 isoform X1

    Conserved Domains (1) summary
    TIGR01661
    Location:206529
    ELAV_HUD_SF; ELAV/HuD family splicing factor
  41. XM_036163697.1XP_036019590.1  ELAV-like protein 2 isoform X1

    Conserved Domains (1) summary
    TIGR01661
    Location:206529
    ELAV_HUD_SF; ELAV/HuD family splicing factor
  42. XM_036163698.1XP_036019591.1  ELAV-like protein 2 isoform X1

    Conserved Domains (1) summary
    TIGR01661
    Location:206529
    ELAV_HUD_SF; ELAV/HuD family splicing factor
  43. XM_036163720.1XP_036019613.1  ELAV-like protein 2 isoform X14

    Conserved Domains (1) summary
    TIGR01661
    Location:36359
    ELAV_HUD_SF; ELAV/HuD family splicing factor
  44. XM_036163710.1XP_036019603.1  ELAV-like protein 2 isoform X2

    Conserved Domains (1) summary
    TIGR01661
    Location:206528
    ELAV_HUD_SF; ELAV/HuD family splicing factor
  45. XM_036163723.1XP_036019616.1  ELAV-like protein 2 isoform X15

    Conserved Domains (1) summary
    TIGR01661
    Location:36358
    ELAV_HUD_SF; ELAV/HuD family splicing factor
  46. XM_030253241.2XP_030109101.1  ELAV-like protein 2 isoform X15

    Conserved Domains (1) summary
    TIGR01661
    Location:36358
    ELAV_HUD_SF; ELAV/HuD family splicing factor
  47. XM_030253244.2XP_030109104.1  ELAV-like protein 2 isoform X16

    Conserved Domains (1) summary
    TIGR01661
    Location:36346
    ELAV_HUD_SF; ELAV/HuD family splicing factor
  48. XM_006502791.4XP_006502854.1  ELAV-like protein 2 isoform X14

    See identical proteins and their annotated locations for XP_006502854.1

    UniProtKB/Swiss-Prot
    Q60899
    UniProtKB/TrEMBL
    Q564D8
    Conserved Domains (1) summary
    TIGR01661
    Location:36359
    ELAV_HUD_SF; ELAV/HuD family splicing factor
  49. XM_017319987.3XP_017175476.1  ELAV-like protein 2 isoform X7

    UniProtKB/TrEMBL
    B1AXZ5
    Conserved Domains (1) summary
    TIGR01661
    Location:65388
    ELAV_HUD_SF; ELAV/HuD family splicing factor
  50. XM_030253237.2XP_030109097.1  ELAV-like protein 2 isoform X8

    Conserved Domains (1) summary
    TIGR01661
    Location:65387
    ELAV_HUD_SF; ELAV/HuD family splicing factor
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