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Kcnq2 potassium voltage-gated channel, subfamily Q, member 2 [ Mus musculus (house mouse) ]

Gene ID: 16536, updated on 16-Oct-2021

Summary

Official Symbol
Kcnq2provided by MGI
Official Full Name
potassium voltage-gated channel, subfamily Q, member 2provided by MGI
Primary source
MGI:MGI:1309503
See related
Ensembl:ENSMUSG00000016346
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
KQT2; HNSPC; Nmf134
Expression
Biased expression in cortex adult (RPKM 26.0), frontal lobe adult (RPKM 26.0) and 5 other tissues See more
Orthologs
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Genomic context

See Kcnq2 in Genome Data Viewer
Location:
2 H4; 2 103.57 cM
Exon count:
21
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (180717372..180777368, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (181075579..181135580, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (180810284..180869930, complement)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene collagen, type XX, alpha 1 Neighboring gene cholinergic receptor, nicotinic, alpha polypeptide 4 Neighboring gene eukaryotic translation elongation factor 1 alpha 2 Neighboring gene predicted gene, 24892

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (8)  1 citation
  • Chemically induced (ENU) (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables ankyrin binding ISO
Inferred from Sequence Orthology
more info
 
enables calmodulin binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables calmodulin binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables calmodulin binding ISO
Inferred from Sequence Orthology
more info
 
enables delayed rectifier potassium channel activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables ion channel activity IEA
Inferred from Electronic Annotation
more info
 
enables potassium channel activity IEA
Inferred from Electronic Annotation
more info
 
enables protein N-terminus binding ISO
Inferred from Sequence Orthology
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables voltage-gated ion channel activity IGI
Inferred from Genetic Interaction
more info
PubMed 
enables voltage-gated potassium channel activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables voltage-gated potassium channel activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within ion transport IEA
Inferred from Electronic Annotation
more info
 
involved_in ion transport IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within membrane hyperpolarization IMP
Inferred from Mutant Phenotype
more info
 
involved_in potassium ion transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in potassium ion transmembrane transport ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within potassium ion transport IEA
Inferred from Electronic Annotation
more info
 
involved_in potassium ion transport IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within regulation of ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within transmission of nerve impulse IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
is_active_in axon initial segment IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in axon initial segment IDA
Inferred from Direct Assay
more info
PubMed 
located_in cell surface IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in integral component of membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in integral component of plasma membrane ISO
Inferred from Sequence Orthology
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in node of Ranvier IDA
Inferred from Direct Assay
more info
PubMed 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 
part_of protein-containing complex ISO
Inferred from Sequence Orthology
more info
 
part_of voltage-gated potassium channel complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of voltage-gated potassium channel complex IGI
Inferred from Genetic Interaction
more info
PubMed 
part_of voltage-gated potassium channel complex ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
potassium voltage-gated channel subfamily KQT member 2
Names
KQT-like 2
potassium channel subunit alpha KvLQT2
voltage-gated potassium channel subunit Kv7.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001003824.2NP_001003824.1  potassium voltage-gated channel subfamily KQT member 2 isoform 2

    See identical proteins and their annotated locations for NP_001003824.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks two alternate in-frame exons but includes an additional in-frame exon, and it also contains alternate 3' exon structure resulting in an alternate 3' coding region, compared to variant 1. The encoded isoform (2) has a distinct C-terminus and is shorter than isoform 1.
    Source sequence(s)
    AL450341, BC145453, CJ121810, CJ263767
    Consensus CDS
    CCDS17193.1
    UniProtKB/TrEMBL
    B7ZBV4
    Related
    ENSMUSP00000016491.8, ENSMUST00000016491.14
    Conserved Domains (4) summary
    pfam00520
    Location:119324
    Ion_trans; Ion transport protein
    pfam03520
    Location:444666
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam07885
    Location:240314
    Ion_trans_2; Ion channel
    pfam16642
    Location:675754
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
  2. NM_001003825.3NP_001003825.1  potassium voltage-gated channel subfamily KQT member 2 isoform 3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) lacks two alternate in-frame exons and uses an alternate in-frame splice site, and it also contains alternate 3' exon structure resulting in an alternate 3' coding region, compared to variant 1. The encoded isoform (3) has a distinct C-terminus and is shorter than isoform 1.
    Source sequence(s)
    AL450341, CJ119072, CJ121810, CJ263767
    Consensus CDS
    CCDS17194.1
    UniProtKB/TrEMBL
    B7ZBV6
    Related
    ENSMUSP00000052453.9, ENSMUST00000049792.15
    Conserved Domains (4) summary
    pfam00520
    Location:119324
    Ion_trans; Ion transport protein
    pfam03520
    Location:444661
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam07885
    Location:240314
    Ion_trans_2; Ion channel
    pfam16642
    Location:670749
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
  3. NM_001006668.2NP_001006669.1  potassium voltage-gated channel subfamily KQT member 2 isoform 4

    See identical proteins and their annotated locations for NP_001006669.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) lacks two alternate in-frame exons but includes an additional in-frame exon, it uses an alternate in-frame splice site, and it also contains alternate 3' exon structure resulting in an alternate 3' coding region, compared to variant 1. The encoded isoform (4) has a distinct C-terminus and is shorter than isoform 1.
    Source sequence(s)
    AL450341, CJ119072, CJ121810, CJ263767
    Consensus CDS
    CCDS17195.1
    UniProtKB/TrEMBL
    B7ZBV8
    Related
    ENSMUSP00000099336.4, ENSMUST00000103047.10
    Conserved Domains (4) summary
    pfam00520
    Location:119324
    Ion_trans; Ion transport protein
    pfam03520
    Location:432654
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam07885
    Location:240314
    Ion_trans_2; Ion channel
    pfam16642
    Location:663742
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
  4. NM_001006669.2NP_001006670.1  potassium voltage-gated channel subfamily KQT member 2 isoform 5

    See identical proteins and their annotated locations for NP_001006670.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) lacks two alternate in-frame exons, and it also contains alternate 3' exon structure resulting in an alternate 3' coding region, compared to variant 1. The encoded isoform (5) has a distinct C-terminus and is shorter than isoform 1.
    Source sequence(s)
    AL450341, CJ119072, CJ121810, CJ263767
    Consensus CDS
    CCDS17196.1
    UniProtKB/TrEMBL
    B7ZBV7
    Related
    ENSMUSP00000099337.4, ENSMUST00000103048.10
    Conserved Domains (4) summary
    pfam00520
    Location:119324
    Ion_trans; Ion transport protein
    pfam03520
    Location:444630
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam07885
    Location:240314
    Ion_trans_2; Ion channel
    pfam16642
    Location:639718
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
  5. NM_001006674.2NP_001006675.1  potassium voltage-gated channel subfamily KQT member 2 isoform 6

    See identical proteins and their annotated locations for NP_001006675.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) lacks two alternate in-frame exons, and it also contains alternate 3' exon structure resulting in an alternate 3' coding region, compared to variant 1. The encoded isoform (6) has a distinct C-terminus and is shorter than isoform 1.
    Source sequence(s)
    AL450341, CJ119072, CJ121810, CJ263767
    Consensus CDS
    CCDS17197.1
    UniProtKB/Swiss-Prot
    Q9Z351
    UniProtKB/TrEMBL
    B7ZBV5
    Related
    ENSMUSP00000080243.7, ENSMUST00000081528.13
    Conserved Domains (3) summary
    pfam00520
    Location:119324
    Ion_trans; Ion transport protein
    pfam03520
    Location:444561
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam07885
    Location:240314
    Ion_trans_2; Ion channel
  6. NM_001302888.1NP_001289817.1  potassium voltage-gated channel subfamily KQT member 2 isoform 13

    Status: VALIDATED

    Description
    Transcript Variant: This variant (13) lacks an alternate in-frame exon and uses an alternate in-frame splice site, resulting in an isoform (13) that is shorter than isoform 1.
    Source sequence(s)
    AK139411, AL450341, CJ119072, CJ121810, CJ263767
    UniProtKB/Swiss-Prot
    Q9Z351
    Related
    ENSMUSP00000099338.4, ENSMUST00000103049.10
    Conserved Domains (5) summary
    pfam00520
    Location:119324
    Ion_trans; Ion transport protein
    pfam03520
    Location:454639
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam07885
    Location:240314
    Ion_trans_2; Ion channel
    pfam11956
    Location:757847
    KCNQC3-Ank-G_bd; Ankyrin-G binding motif of KCNQ2-3
    pfam16642
    Location:648735
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
  7. NM_010611.3NP_034741.2  potassium voltage-gated channel subfamily KQT member 2 isoform 1

    See identical proteins and their annotated locations for NP_034741.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
    Source sequence(s)
    AK135059, AK139411, AL450341, CJ119072, CJ121810, CJ125938, CJ263767
    Consensus CDS
    CCDS17198.1
    UniProtKB/Swiss-Prot
    Q9Z351
    UniProtKB/TrEMBL
    B7ZBV9, Q3UY10
    Related
    ENSMUSP00000122915.3, ENSMUST00000149964.9
    Conserved Domains (5) summary
    pfam00520
    Location:119324
    Ion_trans; Ion transport protein
    pfam03520
    Location:472658
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam07885
    Location:240314
    Ion_trans_2; Ion channel
    pfam11956
    Location:776866
    KCNQC3-Ank-G_bd; Ankyrin-G binding motif of KCNQ2-3
    pfam16642
    Location:667754
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    180717372..180777368 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017315767.3XP_017171256.1  potassium voltage-gated channel subfamily KQT member 2 isoform X24

    Conserved Domains (4) summary
    pfam00520
    Location:92324
    Ion_trans; Ion transport protein
    pfam03520
    Location:426612
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam11956
    Location:733826
    KCNQC3-Ank-G_bd; Ankyrin-G binding motif of KCNQ2-3
    pfam16642
    Location:627714
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
  2. XM_017315754.3XP_017171243.1  potassium voltage-gated channel subfamily KQT member 2 isoform X17

    Conserved Domains (4) summary
    pfam00520
    Location:92324
    Ion_trans; Ion transport protein
    pfam03520
    Location:426648
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam11956
    Location:769862
    KCNQC3-Ank-G_bd; Ankyrin-G binding motif of KCNQ2-3
    pfam16642
    Location:663750
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
  3. XM_030247788.2XP_030103648.1  potassium voltage-gated channel subfamily KQT member 2 isoform X21

    Conserved Domains (4) summary
    pfam00520
    Location:92324
    Ion_trans; Ion transport protein
    pfam03520
    Location:438623
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam11956
    Location:744837
    KCNQC3-Ank-G_bd; Ankyrin-G binding motif of KCNQ2-3
    pfam16642
    Location:638725
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
  4. XM_030247775.2XP_030103635.1  potassium voltage-gated channel subfamily KQT member 2 isoform X9

    Conserved Domains (4) summary
    pfam00520
    Location:92324
    Ion_trans; Ion transport protein
    pfam03520
    Location:438690
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam11956
    Location:811904
    KCNQC3-Ank-G_bd; Ankyrin-G binding motif of KCNQ2-3
    pfam16642
    Location:705792
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
  5. XM_006500567.3XP_006500630.1  potassium voltage-gated channel subfamily KQT member 2 isoform X20

    UniProtKB/TrEMBL
    A0A0G2JFQ2
    Related
    ENSMUSP00000143263.2, ENSMUST00000197015.5
    Conserved Domains (4) summary
    pfam00520
    Location:92324
    Ion_trans; Ion transport protein
    pfam03520
    Location:438624
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam11956
    Location:745838
    KCNQC3-Ank-G_bd; Ankyrin-G binding motif of KCNQ2-3
    pfam16642
    Location:639726
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
  6. XM_017315747.3XP_017171236.1  potassium voltage-gated channel subfamily KQT member 2 isoform X14

    Conserved Domains (4) summary
    pfam00520
    Location:92324
    Ion_trans; Ion transport protein
    pfam03520
    Location:438660
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam11956
    Location:781874
    KCNQC3-Ank-G_bd; Ankyrin-G binding motif of KCNQ2-3
    pfam16642
    Location:675762
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
  7. XM_017315751.3XP_017171240.1  potassium voltage-gated channel subfamily KQT member 2 isoform X15

    Conserved Domains (4) summary
    pfam00520
    Location:92324
    Ion_trans; Ion transport protein
    pfam03520
    Location:438655
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam11956
    Location:776869
    KCNQC3-Ank-G_bd; Ankyrin-G binding motif of KCNQ2-3
    pfam16642
    Location:670757
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
  8. XM_017315743.3XP_017171232.1  potassium voltage-gated channel subfamily KQT member 2 isoform X8

    Conserved Domains (4) summary
    pfam00520
    Location:92324
    Ion_trans; Ion transport protein
    pfam03520
    Location:438691
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam11956
    Location:812905
    KCNQC3-Ank-G_bd; Ankyrin-G binding motif of KCNQ2-3
    pfam16642
    Location:706793
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
  9. XM_036158776.1XP_036014669.1  potassium voltage-gated channel subfamily KQT member 2 isoform X18

    Conserved Domains (4) summary
    pfam00520
    Location:92324
    Ion_trans; Ion transport protein
    pfam03520
    Location:456641
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam11956
    Location:755855
    KCNQC3-Ank-G_bd; Ankyrin-G binding motif of KCNQ2-3
    pfam16642
    Location:656743
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
  10. XM_030247769.2XP_030103629.1  potassium voltage-gated channel subfamily KQT member 2 isoform X4

    Conserved Domains (4) summary
    pfam00520
    Location:92324
    Ion_trans; Ion transport protein
    pfam03520
    Location:456708
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam11956
    Location:829922
    KCNQC3-Ank-G_bd; Ankyrin-G binding motif of KCNQ2-3
    pfam16642
    Location:723810
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
  11. XM_017315740.3XP_017171229.1  potassium voltage-gated channel subfamily KQT member 2 isoform X3

    Conserved Domains (4) summary
    pfam00520
    Location:92324
    Ion_trans; Ion transport protein
    pfam03520
    Location:456709
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam11956
    Location:830923
    KCNQC3-Ank-G_bd; Ankyrin-G binding motif of KCNQ2-3
    pfam16642
    Location:724811
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
  12. XM_006500568.3XP_006500631.1  potassium voltage-gated channel subfamily KQT member 2 isoform X23

    UniProtKB/TrEMBL
    B7ZBW2
    Related
    ENSMUSP00000099339.5, ENSMUST00000103050.10
    Conserved Domains (4) summary
    pfam00520
    Location:92324
    Ion_trans; Ion transport protein
    pfam03520
    Location:436621
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam11956
    Location:742835
    KCNQC3-Ank-G_bd; Ankyrin-G binding motif of KCNQ2-3
    pfam16642
    Location:636723
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
  13. XM_017315763.3XP_017171252.1  potassium voltage-gated channel subfamily KQT member 2 isoform X22

    Related
    ENSMUSP00000123488.2, ENSMUST00000129695.8
    Conserved Domains (4) summary
    pfam00520
    Location:92324
    Ion_trans; Ion transport protein
    pfam03520
    Location:436622
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam11956
    Location:743836
    KCNQC3-Ank-G_bd; Ankyrin-G binding motif of KCNQ2-3
    pfam16642
    Location:637724
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
  14. XM_017315744.3XP_017171233.1  potassium voltage-gated channel subfamily KQT member 2 isoform X10

    Conserved Domains (4) summary
    pfam00520
    Location:92324
    Ion_trans; Ion transport protein
    pfam03520
    Location:436689
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam11956
    Location:810903
    KCNQC3-Ank-G_bd; Ankyrin-G binding motif of KCNQ2-3
    pfam16642
    Location:704791
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
  15. XM_030247772.2XP_030103632.1  potassium voltage-gated channel subfamily KQT member 2 isoform X7

    Conserved Domains (4) summary
    pfam00520
    Location:92324
    Ion_trans; Ion transport protein
    pfam03520
    Location:448700
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam11956
    Location:821914
    KCNQC3-Ank-G_bd; Ankyrin-G binding motif of KCNQ2-3
    pfam16642
    Location:715802
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
  16. XM_006500565.3XP_006500628.1  potassium voltage-gated channel subfamily KQT member 2 isoform X19

    UniProtKB/TrEMBL
    B7ZBW1
    Related
    ENSMUSP00000099340.3, ENSMUST00000103051.9
    Conserved Domains (4) summary
    pfam00520
    Location:92324
    Ion_trans; Ion transport protein
    pfam03520
    Location:448634
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam11956
    Location:755848
    KCNQC3-Ank-G_bd; Ankyrin-G binding motif of KCNQ2-3
    pfam16642
    Location:649736
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
  17. XM_036158772.1XP_036014665.1  potassium voltage-gated channel subfamily KQT member 2 isoform X13

    Conserved Domains (4) summary
    pfam00520
    Location:92324
    Ion_trans; Ion transport protein
    pfam03520
    Location:448670
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam11956
    Location:784884
    KCNQC3-Ank-G_bd; Ankyrin-G binding motif of KCNQ2-3
    pfam16642
    Location:685772
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
  18. XM_017315742.3XP_017171231.1  potassium voltage-gated channel subfamily KQT member 2 isoform X6

    Conserved Domains (4) summary
    pfam00520
    Location:92324
    Ion_trans; Ion transport protein
    pfam03520
    Location:448701
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam11956
    Location:822915
    KCNQC3-Ank-G_bd; Ankyrin-G binding motif of KCNQ2-3
    pfam16642
    Location:716803
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
  19. XM_017315741.3XP_017171230.1  potassium voltage-gated channel subfamily KQT member 2 isoform X5

    Conserved Domains (4) summary
    pfam00520
    Location:92324
    Ion_trans; Ion transport protein
    pfam03520
    Location:454707
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam11956
    Location:828921
    KCNQC3-Ank-G_bd; Ankyrin-G binding motif of KCNQ2-3
    pfam16642
    Location:722809
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
  20. XM_017315753.3XP_017171242.1  potassium voltage-gated channel subfamily KQT member 2 isoform X16

    Conserved Domains (4) summary
    pfam00520
    Location:92324
    Ion_trans; Ion transport protein
    pfam03520
    Location:466651
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam11956
    Location:772865
    KCNQC3-Ank-G_bd; Ankyrin-G binding motif of KCNQ2-3
    pfam16642
    Location:666753
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
  21. XM_017315738.3XP_017171227.1  potassium voltage-gated channel subfamily KQT member 2 isoform X2

    Conserved Domains (4) summary
    pfam00520
    Location:92324
    Ion_trans; Ion transport protein
    pfam03520
    Location:466718
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam11956
    Location:839932
    KCNQC3-Ank-G_bd; Ankyrin-G binding motif of KCNQ2-3
    pfam16642
    Location:733820
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
  22. XM_011239925.3XP_011238227.1  potassium voltage-gated channel subfamily KQT member 2 isoform X11

    Conserved Domains (4) summary
    pfam00520
    Location:92324
    Ion_trans; Ion transport protein
    pfam03520
    Location:466688
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam11956
    Location:809902
    KCNQC3-Ank-G_bd; Ankyrin-G binding motif of KCNQ2-3
    pfam16642
    Location:703790
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
  23. XM_017315746.3XP_017171235.1  potassium voltage-gated channel subfamily KQT member 2 isoform X12

    Conserved Domains (4) summary
    pfam00520
    Location:92324
    Ion_trans; Ion transport protein
    pfam03520
    Location:466683
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam11956
    Location:804897
    KCNQC3-Ank-G_bd; Ankyrin-G binding motif of KCNQ2-3
    pfam16642
    Location:698785
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
  24. XM_017315735.3XP_017171224.1  potassium voltage-gated channel subfamily KQT member 2 isoform X1

    Conserved Domains (4) summary
    pfam00520
    Location:92324
    Ion_trans; Ion transport protein
    pfam03520
    Location:466719
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam11956
    Location:840933
    KCNQC3-Ank-G_bd; Ankyrin-G binding motif of KCNQ2-3
    pfam16642
    Location:734821
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
  25. XM_030247798.2XP_030103658.1  potassium voltage-gated channel subfamily KQT member 2 isoform X26

    Conserved Domains (4) summary
    pfam00520
    Location:1151
    Ion_trans; Ion transport protein
    pfam03520
    Location:265518
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam11956
    Location:639732
    KCNQC3-Ank-G_bd; Ankyrin-G binding motif of KCNQ2-3
    pfam16642
    Location:533620
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
  26. XM_036158780.1XP_036014673.1  potassium voltage-gated channel subfamily KQT member 2 isoform X27

    Conserved Domains (3) summary
    pfam03520
    Location:17270
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam11956
    Location:384484
    KCNQC3-Ank-G_bd; Ankyrin-G binding motif of KCNQ2-3
    pfam16642
    Location:285372
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
  27. XM_030247797.1XP_030103657.1  potassium voltage-gated channel subfamily KQT member 2 isoform X25

    Conserved Domains (4) summary
    pfam00520
    Location:1151
    Ion_trans; Ion transport protein
    pfam03520
    Location:293546
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam11956
    Location:667760
    KCNQC3-Ank-G_bd; Ankyrin-G binding motif of KCNQ2-3
    pfam16642
    Location:561648
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
  28. XM_017315771.3XP_017171260.1  potassium voltage-gated channel subfamily KQT member 2 isoform X27

    Conserved Domains (3) summary
    pfam03520
    Location:17270
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam11956
    Location:384484
    KCNQC3-Ank-G_bd; Ankyrin-G binding motif of KCNQ2-3
    pfam16642
    Location:285372
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
  29. XM_017315781.3XP_017171270.1  potassium voltage-gated channel subfamily KQT member 2 isoform X28

    Conserved Domains (3) summary
    pfam03520
    Location:17269
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam11956
    Location:390483
    KCNQC3-Ank-G_bd; Ankyrin-G binding motif of KCNQ2-3
    pfam16642
    Location:284371
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
  30. XM_017315772.3XP_017171261.1  potassium voltage-gated channel subfamily KQT member 2 isoform X27

    Conserved Domains (3) summary
    pfam03520
    Location:17270
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam11956
    Location:384484
    KCNQC3-Ank-G_bd; Ankyrin-G binding motif of KCNQ2-3
    pfam16642
    Location:285372
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
  31. XM_017315776.3XP_017171265.1  potassium voltage-gated channel subfamily KQT member 2 isoform X27

    Conserved Domains (3) summary
    pfam03520
    Location:17270
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam11956
    Location:384484
    KCNQC3-Ank-G_bd; Ankyrin-G binding motif of KCNQ2-3
    pfam16642
    Location:285372
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2
  32. XM_017315773.3XP_017171262.1  potassium voltage-gated channel subfamily KQT member 2 isoform X27

    Conserved Domains (3) summary
    pfam03520
    Location:17270
    KCNQ_channel; KCNQ voltage-gated potassium channel
    pfam11956
    Location:384484
    KCNQC3-Ank-G_bd; Ankyrin-G binding motif of KCNQ2-3
    pfam16642
    Location:285372
    KCNQ2_u3; Unstructured region on Potassium channel subunit alpha KvLQT2

RNA

  1. XR_003950848.2 RNA Sequence

  2. XR_004938437.1 RNA Sequence

  3. XR_004938426.1 RNA Sequence

  4. XR_004938432.1 RNA Sequence

  5. XR_001781086.3 RNA Sequence

  6. XR_001781085.3 RNA Sequence

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001006675.1: Suppressed sequence

    Description
    NM_001006675.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein, and the transcript appears to retain intronic sequence at its 3' end.
  2. NM_001006676.1: Suppressed sequence

    Description
    NM_001006676.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein, and the transcript appears to retain intronic sequence at its 3' end.
  3. NM_001006677.1: Suppressed sequence

    Description
    NM_001006677.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein, and the transcript appears to retain intronic sequence at its 3' end.
  4. NM_001006678.1: Suppressed sequence

    Description
    NM_001006678.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein, and the transcript appears incomplete at the 3' end.
  5. NM_001006679.1: Suppressed sequence

    Description
    NM_001006679.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein, and the transcript appears to retain intronic sequence at its 3' end.
  6. NM_001006680.1: Suppressed sequence

    Description
    NM_001006680.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein, and the transcript appears to retain intronic sequence at its 3' end.
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