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Lmnb1 lamin B1 [ Mus musculus (house mouse) ]

Gene ID: 16906, updated on 13-Jul-2021

Summary

Official Symbol
Lmnb1provided by MGI
Official Full Name
lamin B1provided by MGI
Primary source
MGI:MGI:96795
See related
Ensembl:ENSMUSG00000024590
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Expression
Broad expression in CNS E11.5 (RPKM 89.9), thymus adult (RPKM 41.9) and 17 other tissues See more
Orthologs
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Genomic context

See Lmnb1 in Genome Data Viewer
Location:
18 D3; 18 30.84 cM
Exon count:
11
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (56840885..56886496)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (56707813..56753424)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 18 NC_000084.5 (56867467..56913078)

Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 50288 Neighboring gene predicted gene, 41738 Neighboring gene membrane associated ring-CH-type finger 3 Neighboring gene predicted gene 15345 Neighboring gene VISTA enhancer mm109

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables JUN kinase binding NAS
Non-traceable Author Statement
more info
PubMed 
enables double-stranded DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
enables phospholipase binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables sequence-specific double-stranded DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in intermediate filament IEA
Inferred from Electronic Annotation
more info
 
located_in lamin filament IDA
Inferred from Direct Assay
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in nuclear envelope IDA
Inferred from Direct Assay
more info
PubMed 
colocalizes_with nuclear envelope ISO
Inferred from Sequence Orthology
more info
 
located_in nuclear envelope ISO
Inferred from Sequence Orthology
more info
 
located_in nuclear envelope TAS
Traceable Author Statement
more info
 
located_in nuclear inner membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in nuclear lamina ISO
Inferred from Sequence Orthology
more info
 
located_in nuclear matrix IDA
Inferred from Direct Assay
more info
PubMed 
located_in nuclear matrix ISO
Inferred from Sequence Orthology
more info
 
located_in nuclear membrane ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleoplasm TAS
Traceable Author Statement
more info
 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_010721.2NP_034851.2  lamin-B1

    See identical proteins and their annotated locations for NP_034851.2

    Status: VALIDATED

    Source sequence(s)
    AK132252, BC052729
    Consensus CDS
    CCDS29261.1
    UniProtKB/Swiss-Prot
    P14733
    Related
    ENSMUSP00000025486.9, ENSMUST00000025486.9
    Conserved Domains (2) summary
    pfam00038
    Location:32388
    Filament; Intermediate filament protein
    pfam00932
    Location:440544
    LTD; Lamin Tail Domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000084.7 Reference GRCm39 C57BL/6J

    Range
    56840885..56886496
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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