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Mbl2 mannose-binding lectin (protein C) 2 [ Mus musculus (house mouse) ]

Gene ID: 17195, updated on 23-Jun-2021

Summary

Official Symbol
Mbl2provided by MGI
Official Full Name
mannose-binding lectin (protein C) 2provided by MGI
Primary source
MGI:MGI:96924
See related
Ensembl:ENSMUSG00000024863
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
MB; MBL; MBL-; MBP-; L-MBP; MBL-C; MBP-C; RARF/P28A
Expression
Biased expression in liver adult (RPKM 158.5), liver E18 (RPKM 28.1) and 1 other tissue See more
Orthologs
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Genomic context

See Mbl2 in Genome Data Viewer
Location:
19 C1; 19 25.14 cM
Exon count:
6
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (30210306..30217087)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (30232906..30239687)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 19 NC_000085.5 (30307447..30314172)

Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene ubiquitin-like, containing PHD and RING finger domains 2 Neighboring gene glycine decarboxylase Neighboring gene ribosomal protein L31, pseudogene 20 Neighboring gene protein dpy-30 homolog Neighboring gene predicted gene, 36319

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1)  1 citation
  • Endonuclease-mediated (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables calcium-dependent protein binding ISO
Inferred from Sequence Orthology
more info
 
enables carbohydrate binding IEA
Inferred from Electronic Annotation
more info
 
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
 
enables mannose binding ISO
Inferred from Sequence Orthology
more info
 
enables signaling receptor binding ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
part_of collagen trimer IEA
Inferred from Electronic Annotation
more info
 
is_active_in collagen-containing extracellular matrix IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in extracellular space IDA
Inferred from Direct Assay
more info
PubMed 
located_in extracellular space ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
mannose-binding protein C
Names
RA-reactive factor P28A subunit
mannan-binding protein
mannose binding lectin, liver (C)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001365058.1NP_001351987.1  mannose-binding protein C precursor

    Status: VALIDATED

    Source sequence(s)
    AC157986
    Consensus CDS
    CCDS29742.1
    Conserved Domains (2) summary
    pfam01391
    Location:3693
    Collagen; Collagen triple helix repeat (20 copies)
    cl02432
    Location:132242
    CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain
  2. NM_010776.2NP_034906.1  mannose-binding protein C precursor

    See identical proteins and their annotated locations for NP_034906.1

    Status: VALIDATED

    Source sequence(s)
    AK149484, DV653788
    Consensus CDS
    CCDS29742.1
    UniProtKB/Swiss-Prot
    P41317
    UniProtKB/TrEMBL
    Q3UEK1
    Related
    ENSMUSP00000025797.6, ENSMUST00000025797.7
    Conserved Domains (2) summary
    pfam01391
    Location:3693
    Collagen; Collagen triple helix repeat (20 copies)
    cl02432
    Location:132242
    CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000085.7 Reference GRCm39 C57BL/6J

    Range
    30210306..30217087
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006526730.1XP_006526793.1  mannose-binding protein C isoform X1

    See identical proteins and their annotated locations for XP_006526793.1

    UniProtKB/Swiss-Prot
    P41317
    UniProtKB/TrEMBL
    Q3UEK1
    Conserved Domains (2) summary
    pfam01391
    Location:3693
    Collagen; Collagen triple helix repeat (20 copies)
    cl02432
    Location:132242
    CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain
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