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F55F8.3 Periodic tryptophan protein 2 homolog [ Caenorhabditis elegans ]

Gene ID: 172224, updated on 11-Apr-2024

Summary

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Gene symbol
F55F8.3
Gene description
Periodic tryptophan protein 2 homolog
Primary source
WormBase:WBGene00018891
Locus tag
CELE_F55F8.3
See related
AllianceGenome:WB:WBGene00018891
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) and ribosomal small subunit assembly. Predicted to be part of Pwp2p-containing subcomplex of 90S preribosome and small-subunit processome. Orthologous to human PWP2 (PWP2 small subunit processome component). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: I
Exon count:
13
Sequence:
Chromosome: I; NC_003279.8 (5649756..5653648, complement)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Protein-tyrosine phosphatase catalytic domain-containing protein Neighboring gene Col_cuticle_N domain-containing protein Neighboring gene ATP-dependent RNA helicase Neighboring gene CBF1-interacting co-repressor CIR N-terminal domain-containing protein Neighboring gene Ribosome biogenesis protein WDR12 homolog Neighboring gene Mitochondrial fission factor

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Germline Maintenance Through the Multifaceted Activities of GLH/Vasa in Caenorhabditis elegans P Granules. Marnik EA, et al. Genetics, 2019 Nov. PMID 31506335, Free PMC Article
  2. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
  3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in ribosomal small subunit assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in ribosome biogenesis IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of Pwp2p-containing subcomplex of 90S preribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleolus IEA
Inferred from Electronic Annotation
more info
  
part_of small-subunit processome IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Periodic tryptophan protein 2 homolog
NP_491653.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    5649756..5653648 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_059252.6 → NP_491653.2  Periodic tryptophan protein 2 homolog [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_491653.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P91341
    Conserved Domains (4) summary
    COG2319
    Location:248 → 618
    WD40; WD40 repeat [General function prediction only]
    pfam04003
    Location:760 → 861
    Utp12; Dip2/Utp12 Family
    sd00039
    Location:318 → 358
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:321 → 608
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P91341.2

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