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HpV1agp4 E1 [ Mupapillomavirus 1 ]

Gene ID: 1724533, updated on 29-Jul-2022

Summary

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Gene symbol
HpV1agp4
Gene description
E1
Locus tag
HpV1agp4
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mupapillomavirus 1 (type: 1a)
Lineage
Viruses; dsDNA viruses, no RNA stage; Papillomaviridae; Mupapillomavirus
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Genomic context

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Sequence:
NC_001356.1 (812..2650)

NC_001356.1Genomic Context describing neighboring genes Neighboring gene E6 protein Neighboring gene E8 protein Neighboring gene E7 protein Neighboring gene regulatory protein E2 Neighboring gene minor capsid protein L2 Neighboring gene major capsid L1 protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001356.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Human papillomavirus 1a complete DNA sequence: a novel type of genome organization among papovaviridae. Danos O, et al. EMBO J, 1982. PMID 6325156, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

General protein information

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Preferred Names
E1
NP_597739.1
  • E1; The Papillomaviriuses are icosahedral dsDNA viruses that encode 7 early proteins, E1 to E7, and 2 late structural proteins L1 and L2. Host infection by members of the papillomaviruses gives rise to warts and cancer in some instances. The E1 helicase protein is an ATP-dependent DNA helicase that facilitates the inititiation of viral DNA replication through its interactions with the viral E2 protein. The E1-E2 complex binds to the viral origin of replication where E1 acts to unwind the DNA and E2 acts as a transcriptional activator.

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001356.1 Reference assembly

    Range
    812..2650
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_597739.1 replication protein E1 [Mupapillomavirus 1]

    See identical proteins and their annotated locations for NP_597739.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P03111
    Conserved Domains (3) summary
    PHA02774
    Location:1 → 612
    PHA02774; E1; Provisional
    pfam00519
    Location:172 → 603
    PPV_E1_C; Papillomavirus helicase
    pfam00524
    Location:1 → 127
    PPV_E1_N; E1 Protein, N terminal domain

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