U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

sqt-1 Cuticle collagen sqt-1 [ Caenorhabditis elegans ]

Gene ID: 174731, updated on 7-Sep-2023

Summary

Go to the top of the page Help
Gene symbol
sqt-1
Gene description
Cuticle collagen sqt-1
Primary source
WormBase:WBGene00005016
Locus tag
CELE_B0491.2
See related
AllianceGenome:WB:WBGene00005016
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
A structural constituent of collagen and cuticulin-based cuticle. Involved in cuticle development involved in collagen and cuticulin-based cuticle molting cycle. Predicted to be part of collagen trimer. [provided by Alliance of Genome Resources, Apr 2022]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: II
Exon count:
3
Sequence:
Chromosome: II; NC_003280.10 (11336693..11337837, complement)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene tRNA-Ala Neighboring gene ncRNA Neighboring gene tRNA-Ala Neighboring gene Regulator of microtubule dynamics protein 1 Neighboring gene Neurotransmitter-gated ion-channel ligand-binding domain-containing protein

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Efficient Transgenesis in Caenorhabditis elegans Using Flp Recombinase-Mediated Cassette Exchange. Nonet ML. Genetics, 2020 Aug. PMID 32513816, Free PMC Article
  2. CRISPR/Cas9 Genome Editing in Caenorhabditis elegans: Evaluation of Templates for Homology-Mediated Repair and Knock-Ins by Homology-Independent DNA Repair. Katic I, et al. G3 (Bethesda), 2015 Jun 3. PMID 26044730, Free PMC Article
  3. Ultrastructural analyses of the Caenorhabditis elegans sqt-1(sc13) left roller mutant. Peixoto CA, et al. J Parasitol, 2000 Apr. PMID 10780544
  4. Proteolytic processing of Caenorhabditis elegans SQT-1 cuticle collagen is inhibited in right roller mutants whereas cross-linking is inhibited in left roller mutants. Yang J, et al. J Biol Chem, 1999 Nov 12. PMID 10551833
  5. The sqt-1 gene of C. elegans encodes a collagen critical for organismal morphogenesis. Kramer JM, et al. Cell, 1988 Nov 18. PMID 3180220

See all (59) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables structural constituent of collagen and cuticulin-based cuticle IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables structural constituent of cuticle IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in anatomical structure development IEA
Inferred from Electronic Annotation
more info
  
involved_in collagen and cuticulin-based cuticle development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in cuticle development involved in collagen and cuticulin-based cuticle molting cycle IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
part_of collagen trimer IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
Cuticle collagen sqt-1
NP_001369874.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    11336693..11337837 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001383951.2 → NP_001369874.1  Cuticle collagen sqt-1 [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P12114, Q17509
    Conserved Domains (3) summary
    smart01088
    Location:8 → 57
    Col_cuticle_N; Nematode cuticle collagen N-terminal domain
    PHA03169
    Location:132 → 293
    PHA03169; hypothetical protein; Provisional
    pfam01391
    Location:170 → 225
    Collagen; Collagen triple helix repeat (20 copies)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P12114.2

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Tools