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rpia-1 Probable-ribose 5-phosphate isomerase [ Caenorhabditis elegans ]

Gene ID: 175995, updated on 23-Nov-2023

Summary

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Gene symbol
rpia-1
Gene description
Probable-ribose 5-phosphate isomerase
Primary source
WormBase:WBGene00015101
Locus tag
CELE_B0280.3
See related
AllianceGenome:WB:WBGene00015101
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable ribose-5-phosphate isomerase activity. Predicted to be involved in D-ribose metabolic process and pentose-phosphate shunt, non-oxidative branch. Predicted to be active in intracellular membrane-bounded organelle. Is expressed in head neurons; intestine; nerve ring; pharynx; and tail neurons. Orthologous to human RPIA (ribose 5-phosphate isomerase A). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: III
Exon count:
4
Sequence:
Chromosome: III; NC_003281.10 (7123128..7124332)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Nuclear hormone receptor family member nhr-10 Neighboring gene U3 small nucleolar RNA-associated protein 18 homolog Neighboring gene Uncharacterized protein Neighboring gene WH1 domain-containing protein Neighboring gene Protection of telomeres homolog 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. D-ribose competitively reverses inhibition by D-psicose of larval growth in Caenorhabditis elegans. Sato M, et al. Biol Pharm Bull, 2009 May. PMID 19420771
  2. Dietary restriction by growth in axenic medium induces discrete changes in the transcriptional output of genes involved in energy metabolism in Caenorhabditis elegans. Castelein N, et al. Biotechnol J, 2008 Jun. PMID 18383023
  3. The RNA-binding protein repertoire of Arabidopsis thaliana. Marondedze C, et al. Sci Rep, 2016 Jul 11. PMID 27405932, Free PMC Article
  4. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article
  5. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables isomerase activity IEA
Inferred from Electronic Annotation
more info
  
enables ribose-5-phosphate isomerase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ribose-5-phosphate isomerase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in D-ribose metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in pentose-phosphate shunt IEA
Inferred from Electronic Annotation
more info
  
involved_in pentose-phosphate shunt, non-oxidative branch IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in pentose-phosphate shunt, non-oxidative branch IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Probable-ribose 5-phosphate isomerase
NP_498556.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    7123128..7124332
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_066155.8 → NP_498556.1  Probable-ribose 5-phosphate isomerase [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_498556.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P41994
    Conserved Domains (1) summary
    TIGR00021
    Location:18 → 242
    rpiA; ribose 5-phosphate isomerase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P41994.1

Gene LinkOut

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