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agmo-1 Alkylglycerol monooxygenase [ Caenorhabditis elegans ]

Gene ID: 176695, updated on 23-Nov-2023

Summary

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Gene symbol
agmo-1
Gene description
Alkylglycerol monooxygenase
Primary source
WormBase:WBGene00007210
Locus tag
CELE_BE10.2
See related
AllianceGenome:WB:WBGene00007210
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable glyceryl-ether monooxygenase activity. Predicted to be involved in membrane lipid metabolic process. Predicted to be located in endoplasmic reticulum membrane. Predicted to be integral component of membrane. Predicted to be active in endoplasmic reticulum. Is expressed in hypodermis. Orthologous to human AGMO (alkylglycerol monooxygenase). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: III
Exon count:
8
Sequence:
Chromosome: III; NC_003281.10 (12793386..12798157, complement)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Gamma-aminobutyric acid receptor subunit beta Neighboring gene Ligand-Gated ion Channel Neighboring gene RING-type domain-containing protein Neighboring gene ncRNA Neighboring gene pseudo

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Lipodisqs for eukaryote lipidomics with retention of viability: Sensitivity and resistance to Leucobacter infection linked to C.elegans cuticle composition. Bada Juarez JF, et al. Chem Phys Lipids, 2019 Aug. PMID 31102583
  2. An enhanced C. elegans based platform for toxicity assessment. Xiong H, et al. Sci Rep, 2017 Aug 29. PMID 28852193, Free PMC Article
  3. Cuticle integrity and biogenic amine synthesis in Caenorhabditis elegans require the cofactor tetrahydrobiopterin (BH4). Loer CM, et al. Genetics, 2015 May. PMID 25808955, Free PMC Article
  4. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  5. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables glyceryl-ether monooxygenase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables glyceryl-ether monooxygenase activity IEA
Inferred from Electronic Annotation
more info
  
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in lipid biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in membrane lipid metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Alkylglycerol monooxygenase
NP_499664.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    12793386..12798157 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_067263.9 → NP_499664.2  Alkylglycerol monooxygenase [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_499664.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O17554
    UniProtKB/TrEMBL
    A0A0H3W5B8
    Conserved Domains (2) summary
    COG3000
    Location:104 → 293
    ERG3; Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily [Lipid transport and metabolism]
    pfam04116
    Location:130 → 262
    FA_hydroxylase; Fatty acid hydroxylase superfamily
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O17554.2

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