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hsp-16.11 Heat shock protein Hsp-16.1/Hsp-16.11 [ Caenorhabditis elegans ]

Gene ID: 179289, updated on 23-Nov-2023

Summary

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Gene symbol
hsp-16.11
Gene description
Heat shock protein Hsp-16.1/Hsp-16.11
Primary source
WormBase:WBGene00002017
Locus tag
CELE_T27E4.2
See related
AllianceGenome:WB:WBGene00002017
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable unfolded protein binding activity. Involved in endoplasmic reticulum unfolded protein response. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: V
Exon count:
2
Sequence:
Chromosome: V; NC_003283.11 (9090077..9090604)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Heat shock protein Hsp-16.48/Hsp-16.49 Neighboring gene Heat shock protein Hsp-16.48/Hsp-16.49 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Methylmercury exposure increases lipocalin related (lpr) and decreases activated in blocked unfolded protein response (abu) genes and specific miRNAs in Caenorhabditis elegans. Rudgalvyte M, et al. Toxicol Lett, 2013 Oct 24. PMID 23872261, Free PMC Article
  2. Locus encoding a family of small heat shock genes in Caenorhabditis elegans: two genes duplicated to form a 3.8-kilobase inverted repeat. Russnak RH, et al. Mol Cell Biol, 1985 Jun. PMID 4033652, Free PMC Article
  3. Differential hypoxia response of hsp-16 genes in the nematode. Hong M, et al. J Mol Biol, 2004 Nov 19. PMID 15522291
  4. Caenorhabditis elegans as model system for rapid toxicity assessment of pharmaceutical compounds. Dengg M, et al. J Pharmacol Toxicol Methods, 2004 Nov-Dec. PMID 15519907
  5. Lifespan extension in C. elegans by a molecular chaperone dependent upon insulin-like signals. Walker GA, et al. Aging Cell, 2003 Apr. PMID 12882326

See all (26) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables unfolded protein binding ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
involved_in IRE1-mediated unfolded protein response HEP PubMed 
involved_in endoplasmic reticulum unfolded protein response IEP
Inferred from Expression Pattern
more info
 PubMed 

General protein information

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Preferred Names
Heat shock protein Hsp-16.1/Hsp-16.11
NP_505357.1
  • Partially confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    9090077..9090604
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_072956.4 → NP_505357.1  Heat shock protein Hsp-16.1/Hsp-16.11 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_505357.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P34696
    UniProtKB/TrEMBL
    Q21062
    Conserved Domains (2) summary
    cd06526
    Location:42 → 123
    metazoan_ACD; Alpha-crystallin domain (ACD) of metazoan alpha-crystallin-type small(s) heat shock proteins (Hsps). sHsps are small stress induced proteins with monomeric masses between 12 -43 kDa, whose common feature is the Alpha-crystallin domain (ACD). sHsps are ...
    COG0071
    Location:17 → 134
    IbpA; Molecular chaperone IbpA, HSP20 family [Posttranslational modification, protein turnover, chaperones]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P34696.1

Gene LinkOut

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