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Myom2 myomesin 2 [ Mus musculus (house mouse) ]

Gene ID: 17930, updated on 23-Jun-2021

Summary

Official Symbol
Myom2provided by MGI
Official Full Name
myomesin 2provided by MGI
Primary source
MGI:MGI:1328358
See related
Ensembl:ENSMUSG00000031461
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
AW146149
Expression
Biased expression in heart adult (RPKM 109.4), mammary gland adult (RPKM 11.0) and 1 other tissue See more
Orthologs
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Genomic context

See Myom2 in Genome Data Viewer
Location:
8; 8 A1.1
Exon count:
40
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (15107653..15183420)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (15057653..15133420)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (15057653..15133419)

Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 35340 Neighboring gene expressed sequence BB014433 Neighboring gene predicted gene, 24231 Neighboring gene predicted gene, 35392

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC141540, MGC141541

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables actin filament binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables kinase binding ISO
Inferred from Sequence Orthology
more info
 
enables structural constituent of cytoskeleton TAS
Traceable Author Statement
more info
PubMed 
Process Evidence Code Pubs
involved_in muscle contraction IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within muscle contraction IDA
Inferred from Direct Assay
more info
PubMed 
involved_in sarcomere organization ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
is_active_in M band IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in M band IDA
Inferred from Direct Assay
more info
PubMed 
located_in M band ISO
Inferred from Sequence Orthology
more info
 
located_in cytoskeleton TAS
Traceable Author Statement
more info
PubMed 

General protein information

Preferred Names
myomesin-2
Names
skeletal muscle 165kD protein
skeletal muscle 165kDa protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_008664.2NP_032690.2  myomesin-2

    See identical proteins and their annotated locations for NP_032690.2

    Status: VALIDATED

    Source sequence(s)
    AJ001038, AK142174, AV232298, BC115722
    Consensus CDS
    CCDS22123.1
    UniProtKB/TrEMBL
    O55124, Q14BI5, Q3UQS9
    Related
    ENSMUSP00000033842.4, ENSMUST00000033842.4
    Conserved Domains (6) summary
    cd05891
    Location:13441435
    IgI_M-protein_C; C-terminal immunoglobulin (Ig)-like domain of M-protein; member of the I-set of Ig superfamily (IgSF) domains
    smart00409
    Location:940995
    IG; Immunoglobulin
    cd00063
    Location:383475
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd00096
    Location:295299
    Ig; Ig strand B [structural motif]
    cd20951
    Location:154247
    IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
    cl11960
    Location:290372
    Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000074.7 Reference GRCm39 C57BL/6J

    Range
    15107653..15183420
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036153791.1XP_036009684.1  myomesin-2 isoform X2

    Conserved Domains (6) summary
    cd05891
    Location:13441435
    IgI_M-protein_C; C-terminal immunoglobulin (Ig)-like domain of M-protein; member of the I-set of Ig superfamily (IgSF) domains
    smart00409
    Location:940995
    IG; Immunoglobulin
    cd00063
    Location:383475
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd00096
    Location:295299
    Ig; Ig strand B [structural motif]
    cd20951
    Location:154247
    IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
    cl11960
    Location:290372
    Ig; Immunoglobulin domain
  2. XM_006508727.4XP_006508790.1  myomesin-2 isoform X1

    Conserved Domains (5) summary
    cd05891
    Location:13671458
    Ig_M-protein_C; C-terminal immunoglobulin (Ig)-like domain of M-protein (also known as myomesin-2)
    smart00409
    Location:9631018
    IG; Immunoglobulin
    cd00063
    Location:406498
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:177269
    I-set; Immunoglobulin I-set domain
    cl11960
    Location:313395
    Ig; Immunoglobulin domain
  3. XM_036153789.1XP_036009682.1  myomesin-2 isoform X2

    Conserved Domains (6) summary
    cd05891
    Location:13441435
    IgI_M-protein_C; C-terminal immunoglobulin (Ig)-like domain of M-protein; member of the I-set of Ig superfamily (IgSF) domains
    smart00409
    Location:940995
    IG; Immunoglobulin
    cd00063
    Location:383475
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd00096
    Location:295299
    Ig; Ig strand B [structural motif]
    cd20951
    Location:154247
    IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
    cl11960
    Location:290372
    Ig; Immunoglobulin domain
  4. XM_036153790.1XP_036009683.1  myomesin-2 isoform X2

    Conserved Domains (6) summary
    cd05891
    Location:13441435
    IgI_M-protein_C; C-terminal immunoglobulin (Ig)-like domain of M-protein; member of the I-set of Ig superfamily (IgSF) domains
    smart00409
    Location:940995
    IG; Immunoglobulin
    cd00063
    Location:383475
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd00096
    Location:295299
    Ig; Ig strand B [structural motif]
    cd20951
    Location:154247
    IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
    cl11960
    Location:290372
    Ig; Immunoglobulin domain
  5. XM_006508728.5XP_006508791.1  myomesin-2 isoform X2

    See identical proteins and their annotated locations for XP_006508791.1

    UniProtKB/TrEMBL
    Q14BI5
    Conserved Domains (6) summary
    cd05891
    Location:13441435
    IgI_M-protein_C; C-terminal immunoglobulin (Ig)-like domain of M-protein; member of the I-set of Ig superfamily (IgSF) domains
    smart00409
    Location:940995
    IG; Immunoglobulin
    cd00063
    Location:383475
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd00096
    Location:295299
    Ig; Ig strand B [structural motif]
    cd20951
    Location:154247
    IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
    cl11960
    Location:290372
    Ig; Immunoglobulin domain
  6. XM_036153788.1XP_036009681.1  myomesin-2 isoform X2

    Conserved Domains (6) summary
    cd05891
    Location:13441435
    IgI_M-protein_C; C-terminal immunoglobulin (Ig)-like domain of M-protein; member of the I-set of Ig superfamily (IgSF) domains
    smart00409
    Location:940995
    IG; Immunoglobulin
    cd00063
    Location:383475
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd00096
    Location:295299
    Ig; Ig strand B [structural motif]
    cd20951
    Location:154247
    IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
    cl11960
    Location:290372
    Ig; Immunoglobulin domain
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