rpc-25 DNA-directed RNA polymerase III subunit RPC8 [Caenorhabditis elegans] - Gene

Summary

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Gene symbol: rpc-25
Gene description: DNA-directed RNA polymerase III subunit RPC8
Primary source: WormBase:WBGene00014111
Locus tag: CELE_ZK856.10
See related: AllianceGenome:WB:WBGene00014111
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable DNA-directed 5'-3' RNA polymerase activity. Predicted to be involved in transcription initiation from RNA polymerase III promoter. Predicted to be located in nucleus. Predicted to be part of RNA polymerase III complex. Orthologous to human POLR3H (RNA polymerase III subunit H). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See rpc-25 in Genome Data Viewer

Location:: chromosome: V

Exon count:: 3

Sequence:: Chromosome: V; NC_003283.11 (10205680..10206602, complement)

Chromosome V - NC_003283.11 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

ZK856.10 (e-PCR)
- UniSTS:316343

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Process	Evidence Code	Pubs
involved_in DNA-templated transcription	IEA Inferred from Electronic Annotation more info
involved_in DNA-templated transcription initiation	IEA Inferred from Electronic Annotation more info
involved_in transcription initiation at RNA polymerase III promoter	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
part_of DNA-directed RNA polymerase complex	IEA Inferred from Electronic Annotation more info
part_of RNA polymerase III complex	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: DNA-directed RNA polymerase III subunit RPC8

NP_505625.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003283.11 Reference assembly

Range

10205680..10206602 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_073224.5 → NP_505625.1 DNA-directed RNA polymerase III subunit RPC8 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_505625.1

Status: REVIEWED

UniProtKB/TrEMBL

Q23645

Conserved Domains (3) summary

COG1095
Location:1 → 194

RPB7; DNA-directed RNA polymerase, subunit E'/Rpb7 [Transcription]

cd04330
Location:2 → 81

RNAP_III_Rpc25_N; RNAP_III_Rpc25_N: Rpc25, N-terminal ribonucleoprotein (RNP) domain. Rpc25 is a subunit of eukaryotic RNA polymerase (RNAP) III and is homologous to Rpa43 of eukaryotic RNAP I, Rpb7 of eukaryotic RNAP II, and RpoE of archaeal RNAP. Rpc25 has two domains, ...

pfam08292
Location:79 → 194

RNA_pol_Rbc25; RNA polymerase III subunit Rpc25