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Napb N-ethylmaleimide sensitive fusion protein attachment protein beta [ Mus musculus (house mouse) ]

Gene ID: 17957, updated on 8-Jul-2021

Summary

Official Symbol
Napbprovided by MGI
Official Full Name
N-ethylmaleimide sensitive fusion protein attachment protein betaprovided by MGI
Primary source
MGI:MGI:104562
See related
Ensembl:ENSMUSG00000027438
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
S; I4; b-; Brp; I47; E161; Brp14; SNARE; b-SNAP
Expression
Biased expression in frontal lobe adult (RPKM 69.4), cortex adult (RPKM 55.9) and 5 other tissues See more
Orthologs
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Genomic context

See Napb in Genome Data Viewer
Location:
2; 2 G3
Exon count:
11
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (148535905..148574396, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (148693985..148732425, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (148520393..148558156, complement)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene NTF2-related export protein 1 Neighboring gene predicted gene, 46771 Neighboring gene GDNF-inducible zinc finger protein 1 Neighboring gene uncharacterized LOC108168731 Neighboring gene predicted gene, 54122 Neighboring gene cystatin-like 1 Neighboring gene cystatin 11

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables SNARE binding ISO
Inferred from Sequence Orthology
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables soluble NSF attachment protein activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables syntaxin binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables syntaxin binding IDA
Inferred from Direct Assay
more info
PubMed 
enables syntaxin binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in SNARE complex disassembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within SNARE complex disassembly IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in intracellular protein transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within protein transport IEA
Inferred from Electronic Annotation
more info
 
involved_in protein-containing complex disassembly ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of ATPase activity ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of receptor internalization ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of synaptic vesicle priming IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in regulation of synaptic vesicle priming IDA
Inferred from Direct Assay
more info
PubMed 
involved_in regulation of synaptic vesicle priming IEP
Inferred from Expression Pattern
more info
PubMed 
acts_upstream_of_or_within regulation of synaptic vesicle priming IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in regulation of synaptic vesicle priming IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of synaptic vesicle priming IPI
Inferred from Physical Interaction
more info
PubMed 
involved_in synaptic transmission, glutamatergic IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within synaptic transmission, glutamatergic IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in synaptic vesicle endocytosis IC
Inferred by Curator
more info
PubMed 
acts_upstream_of_or_within vesicle-mediated transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
part_of SNARE complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in glutamatergic synapse IDA
Inferred from Direct Assay
more info
PubMed 
located_in glutamatergic synapse IDA
Inferred from Direct Assay
more info
PubMed 
located_in glutamatergic synapse IMP
Inferred from Mutant Phenotype
more info
PubMed 
is_active_in glutamatergic synapse IPI
Inferred from Physical Interaction
more info
PubMed 
located_in glutamatergic synapse IPI
Inferred from Physical Interaction
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in myelin sheath HDA PubMed 
located_in postsynapse ISO
Inferred from Sequence Orthology
more info
 
located_in presynapse ISO
Inferred from Sequence Orthology
more info
 
part_of synaptobrevin 2-SNAP-25-syntaxin-1a complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of synaptobrevin 2-SNAP-25-syntaxin-1a complex IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in vacuolar membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
beta-soluble NSF attachment protein
Names
N-ethylmaleimide-sensitive factor attachment protein beta
SNAP-beta
brain protein 14
brain protein I47

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_019632.3NP_062606.1  beta-soluble NSF attachment protein

    See identical proteins and their annotated locations for NP_062606.1

    Status: PROVISIONAL

    Source sequence(s)
    AL844519, AL928638
    Consensus CDS
    CCDS16842.1
    UniProtKB/Swiss-Prot
    P28663
    Related
    ENSMUSP00000028926.7, ENSMUST00000028926.13
    Conserved Domains (1) summary
    cd15832
    Location:9287
    SNAP; Soluble N-ethylmaleimide-sensitive factor (NSF) Attachment Protein family

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    148535905..148574396 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030248234.1XP_030104094.1  beta-soluble NSF attachment protein isoform X1

    Conserved Domains (1) summary
    pfam14938
    Location:34210
    SNAP; Soluble NSF attachment protein, SNAP

RNA

  1. XR_004938799.1 RNA Sequence

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