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Ndufs4 NADH:ubiquinone oxidoreductase core subunit S4 [ Mus musculus (house mouse) ]

Gene ID: 17993, updated on 6-Jul-2021

Summary

Official Symbol
Ndufs4provided by MGI
Official Full Name
NADH:ubiquinone oxidoreductase core subunit S4provided by MGI
Primary source
MGI:MGI:1343135
See related
Ensembl:ENSMUSG00000021764
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
C1-18k; 6720411N02Rik
Expression
Ubiquitous expression in heart adult (RPKM 45.1), CNS E18 (RPKM 31.6) and 28 other tissues See more
Orthologs
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Genomic context

See Ndufs4 in Genome Data Viewer
Location:
13; 13 D2.2
Exon count:
5
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (114424331..114524630, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (114287795..114388094, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 13 NC_000079.5 (115078003..115178302, complement)

Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene ADP-ribosylation factor-like 15 Neighboring gene RIKEN cDNA A430090L17 gene Neighboring gene predicted gene, 41072 Neighboring gene predicted gene, 41073 Neighboring gene predicted gene, 41074 Neighboring gene follistatin

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Process Evidence Code Pubs
acts_upstream_of_or_within adult behavior IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within adult walking behavior IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within brain development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in brain development ISO
Inferred from Sequence Orthology
more info
 
involved_in cellular respiration ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within cellular response to oxygen levels IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within cognition IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within dopamine metabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in electron transport chain IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within inflammatory response IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within innate immune response IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within mitochondrial respiratory chain complex I assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in mitochondrial respiratory chain complex I assembly ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within neuron death IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of fibroblast proliferation ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within psychomotor behavior IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within reactive oxygen species metabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in reactive oxygen species metabolic process ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within regulation of mitochondrial membrane potential IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within regulation of protein phosphorylation ISO
Inferred from Sequence Orthology
more info
PubMed 
acts_upstream_of_or_within respiratory electron transport chain IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within respiratory system process IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in response to cAMP ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within response to injury involved in regulation of muscle adaptation IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within sensory perception of sound IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within tricarboxylic acid cycle TAS
Traceable Author Statement
more info
PubMed 
acts_upstream_of_or_within visual perception IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
 
part_of mitochondrial respiratory chain complex I IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of mitochondrial respiratory chain complex I IDA
Inferred from Direct Assay
more info
PubMed 
part_of mitochondrial respiratory chain complex I ISO
Inferred from Sequence Orthology
more info
 
located_in mitochondrion HDA PubMed 
located_in mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
 
located_in respirasome IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial
Names
CI-18 kDa
CI-AQDQ
NADH-ubiquinone oxidoreductase 18 kDa subunit
complex I-18 kDa
complex I-AQDQ

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_010887.2NP_035017.2  NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial

    Status: VALIDATED

    Source sequence(s)
    AK011124, AK035175, CJ041886, CJ073528
    Consensus CDS
    CCDS49368.1
    UniProtKB/Swiss-Prot
    Q9CXZ1
    UniProtKB/TrEMBL
    E9QPX3
    Related
    ENSMUSP00000022286.7, ENSMUST00000022286.8
    Conserved Domains (1) summary
    pfam04800
    Location:76170
    ETC_C1_NDUFA4; ETC complex I subunit conserved region

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000079.7 Reference GRCm39 C57BL/6J

    Range
    114424331..114524630 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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