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Ntn3 netrin 3 [ Mus musculus (house mouse) ]

Gene ID: 18209, updated on 23-Jun-2021

Summary

Official Symbol
Ntn3provided by MGI
Official Full Name
netrin 3provided by MGI
Primary source
MGI:MGI:1341188
See related
Ensembl:ENSMUSG00000117406
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Nt; Ntn2l
Expression
Broad expression in limb E14.5 (RPKM 9.9), ovary adult (RPKM 3.7) and 19 other tissues See more
Orthologs
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Genomic context

See Ntn3 in Genome Data Viewer
Location:
17; 17 A3.3
Exon count:
6
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (24422805..24428361, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (24203831..24209387, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 17 NC_000083.5 (24340776..24346332, complement)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene amidohydrolase domain containing 2 Neighboring gene ATPase, H+ transporting, lysosomal V0 subunit C Neighboring gene TBC1 domain family, member 24 Neighboring gene tubulin epsilon and delta complex 2 Neighboring gene cyclin F Neighboring gene microRNA 5134

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables signaling receptor binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables signaling receptor binding IDA
Inferred from Direct Assay
more info
PubMed 
enables signaling receptor binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in animal organ morphogenesis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within axonogenesis TAS
Traceable Author Statement
more info
PubMed 
involved_in dendrite development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in motor neuron axon guidance IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within myoblast fusion ISA
Inferred from Sequence Alignment
more info
PubMed 
acts_upstream_of_or_within regulation of transcription, DNA-templated ISA
Inferred from Sequence Alignment
more info
PubMed 
involved_in tissue development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in Golgi apparatus IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in basement membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in extracellular region IDA
Inferred from Direct Assay
more info
PubMed 
located_in extracellular region TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
netrin-3
Names
netrin-2-like protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_010947.3NP_035077.1  netrin-3 precursor

    See identical proteins and their annotated locations for NP_035077.1

    Status: PROVISIONAL

    Source sequence(s)
    BC094362
    Consensus CDS
    CCDS28478.1
    UniProtKB/Swiss-Prot
    Q9R1A3
    UniProtKB/TrEMBL
    Q52KG2
    Related
    ENSMUSP00000024931.5, ENSMUST00000024931.6
    Conserved Domains (4) summary
    cd00055
    Location:373422
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd03579
    Location:456562
    NTR_netrin-1_like; NTR domain, Netrin-1-like subfamily; The C-terminal NTR domain of netrins is also called domain C in the context of C. elegans netrin UNC-6. Netrins are secreted proteins that function as tropic cues in the direction of axon growth and cell migration ...
    pfam00053
    Location:311362
    Laminin_EGF; Laminin EGF domain
    cl02806
    Location:34253
    Laminin_N; Laminin N-terminal (Domain VI)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    24422805..24428361 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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