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Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 [ Mus musculus (house mouse) ]

Gene ID: 18212, updated on 17-Oct-2021

Summary

Official Symbol
Ntrk2provided by MGI
Official Full Name
neurotrophic tyrosine kinase, receptor, type 2provided by MGI
Primary source
MGI:MGI:97384
See related
Ensembl:ENSMUSG00000055254
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Tkrb; trkB; trk-B; GP145-TrkB/GP95-TrkB
Expression
Biased expression in frontal lobe adult (RPKM 10.3), cortex adult (RPKM 10.2) and 12 other tissues See more
Orthologs
NEW
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Try the new Transcript table

Genomic context

See Ntrk2 in Genome Data Viewer
Location:
13 B1; 13 31.2 cM
Exon count:
22
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (58954286..59281784)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (58806472..59133970)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 13 NC_000079.5 (58907957..59231337)

Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4930455J16 gene Neighboring gene ribosomal protein L13, pseudogene 2 Neighboring gene predicted gene, 40968 Neighboring gene VISTA enhancer mm14 Neighboring gene predicted gene 53063 Neighboring gene predicted gene, 34245 Neighboring gene predicted gene, 34307 Neighboring gene predicted gene, 34354 Neighboring gene predicted gene, 34558

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 
  • Targeted (21)  1 citation
  • Endonuclease-mediated (1) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • C030027L06Rik

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables brain-derived neurotrophic factor binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables brain-derived neurotrophic factor binding IDA
Inferred from Direct Assay
more info
PubMed 
enables brain-derived neurotrophic factor binding ISO
Inferred from Sequence Orthology
more info
 
enables brain-derived neurotrophic factor-activated receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables brain-derived neurotrophic factor-activated receptor activity IDA
Inferred from Direct Assay
more info
PubMed 
enables brain-derived neurotrophic factor-activated receptor activity ISO
Inferred from Sequence Orthology
more info
 
enables kinase activity IEA
Inferred from Electronic Annotation
more info
 
enables neurotrophin binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables neurotrophin binding IDA
Inferred from Direct Assay
more info
PubMed 
enables neurotrophin binding ISO
Inferred from Sequence Orthology
more info
 
enables neurotrophin receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables neurotrophin receptor activity ISO
Inferred from Sequence Orthology
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables protease binding ISO
Inferred from Sequence Orthology
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein homodimerization activity ISO
Inferred from Sequence Orthology
more info
 
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
 
enables protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 
enables receptor tyrosine kinase binding ISO
Inferred from Sequence Orthology
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
enables transmembrane receptor protein tyrosine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables transmembrane receptor protein tyrosine kinase activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in brain-derived neurotrophic factor receptor signaling pathway IDA
Inferred from Direct Assay
more info
PubMed 
involved_in brain-derived neurotrophic factor receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
 
involved_in calcium-mediated signaling using intracellular calcium source IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within cell differentiation IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within cellular response to amino acid stimulus IDA
Inferred from Direct Assay
more info
PubMed 
involved_in cellular response to brain-derived neurotrophic factor stimulus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in cellular response to nerve growth factor stimulus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in central nervous system neuron development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in cerebral cortex development IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within circadian rhythm IEP
Inferred from Expression Pattern
more info
PubMed 
acts_upstream_of_or_within feeding behavior IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within glutamate secretion IPI
Inferred from Physical Interaction
more info
PubMed 
involved_in learning IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in long-term memory ISO
Inferred from Sequence Orthology
more info
 
involved_in long-term synaptic potentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within mechanoreceptor differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in multicellular organism development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within myelination in peripheral nervous system IGI
Inferred from Genetic Interaction
more info
PubMed 
acts_upstream_of_or_within negative regulation of amyloid-beta formation ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of anoikis IDA
Inferred from Direct Assay
more info
PubMed 
involved_in negative regulation of neuron apoptotic process ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within nervous system development IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within neuromuscular junction development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in neuron differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in neuron migration IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within neuronal action potential propagation IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in oligodendrocyte differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in peripheral nervous system neuron development IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within phosphorylation IEA
Inferred from Electronic Annotation
more info
 
NOT involved_in positive regulation of ERK1 and ERK2 cascade IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in positive regulation of MAPK cascade IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in positive regulation of MAPK cascade ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of axonogenesis ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of cell population proliferation ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of gene expression IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within positive regulation of glucocorticoid receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in positive regulation of neuron projection development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in positive regulation of neuron projection development IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within positive regulation of peptidyl-serine phosphorylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of phosphatidylinositol 3-kinase signaling IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in positive regulation of phosphatidylinositol 3-kinase signaling ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within positive regulation of synapse assembly IDA
Inferred from Direct Assay
more info
PubMed 
involved_in positive regulation of synaptic transmission, glutamatergic ISO
Inferred from Sequence Orthology
more info
 
involved_in protein autophosphorylation ISO
Inferred from Sequence Orthology
more info
 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of GTPase activity IDA
Inferred from Direct Assay
more info
PubMed 
involved_in regulation of MAPK cascade ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of dendrite development ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within regulation of metabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of neurotransmitter secretion ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of protein kinase B signaling IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in regulation of protein kinase B signaling IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within retina development in camera-type eye IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within retinal rod cell development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in trans-synaptic signaling by BDNF, modulating synaptic transmission IDA
Inferred from Direct Assay
more info
PubMed 
involved_in trans-synaptic signaling by BDNF, modulating synaptic transmission IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in trans-synaptic signaling by neuropeptide, modulating synaptic transmission IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in trans-synaptic signaling by neuropeptide, modulating synaptic transmission IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in transmembrane receptor protein tyrosine kinase signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within vasculogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
is_active_in axon IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in axon ISO
Inferred from Sequence Orthology
more info
 
is_active_in axon terminus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in axon terminus ISO
Inferred from Sequence Orthology
more info
 
located_in cell junction IEA
Inferred from Electronic Annotation
more info
 
located_in cell projection IEA
Inferred from Electronic Annotation
more info
 
located_in cell surface ISO
Inferred from Sequence Orthology
more info
 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in cytosol IDA
Inferred from Direct Assay
more info
PubMed 
located_in dendrite ISO
Inferred from Sequence Orthology
more info
 
is_active_in dendritic spine IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in dendritic spine ISO
Inferred from Sequence Orthology
more info
 
located_in early endosome IDA
Inferred from Direct Assay
more info
PubMed 
located_in endosome IDA
Inferred from Direct Assay
more info
PubMed 
located_in excitatory synapse ISO
Inferred from Sequence Orthology
more info
 
located_in growth cone ISO
Inferred from Sequence Orthology
more info
 
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in integral component of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in integral component of plasma membrane ISO
Inferred from Sequence Orthology
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in neuronal cell body ISO
Inferred from Sequence Orthology
more info
 
located_in perikaryon ISO
Inferred from Sequence Orthology
more info
 
located_in perinuclear region of cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 
located_in plasma membrane TAS
Traceable Author Statement
more info
 
is_active_in postsynaptic density IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in postsynaptic density IDA
Inferred from Direct Assay
more info
PubMed 
located_in postsynaptic density ISO
Inferred from Sequence Orthology
more info
 
located_in postsynaptic membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in presynaptic active zone ISO
Inferred from Sequence Orthology
more info
 
part_of receptor complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of receptor complex ISO
Inferred from Sequence Orthology
more info
PubMed 
located_in rough endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
 
located_in synapse IEA
Inferred from Electronic Annotation
more info
 
located_in terminal bouton IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
BDNF/NT-3 growth factors receptor
Names
neurotrophic tyrosine receptor kinase type 2
trkB tyrosine kinase
NP_001020245.1
NP_001269890.1
NP_032771.1
XP_006517212.1
XP_006517213.1
XP_006517214.1
XP_006517215.1
XP_030103048.1
XP_030103049.1
XP_036013804.1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001025074.2NP_001020245.1  BDNF/NT-3 growth factors receptor isoform a precursor

    See identical proteins and their annotated locations for NP_001020245.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (a). Both variants 1 and 3 encode the same isoform.
    Source sequence(s)
    AC154755, AK147391, CJ098737
    Consensus CDS
    CCDS26573.1
    UniProtKB/Swiss-Prot
    P15209
    Related
    ENSMUSP00000078757.6, ENSMUST00000079828.7
    Conserved Domains (5) summary
    cd05855
    Location:301379
    Ig_TrkB_d5; Fifth domain (immunoglobulin-like) of Trk receptor TrkB
    cd05093
    Location:531818
    PTKc_TrkB; Catalytic domain of the Protein Tyrosine Kinase, Tropomyosin Related Kinase B
    pfam13855
    Location:92150
    LRR_8; Leucine rich repeat
    pfam16920
    Location:152195
    TPKR_C2; Tyrosine-protein kinase receptor C2 Ig-like domain
    cl11960
    Location:205283
    Ig; Immunoglobulin domain
  2. NM_001282961.1NP_001269890.1  BDNF/NT-3 growth factors receptor isoform a precursor

    See identical proteins and their annotated locations for NP_001269890.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR, compared to variant 1. Both variants 1 and 3 encode the same isoform (a).
    Source sequence(s)
    AC154755, AK147391, AK160789
    Consensus CDS
    CCDS26573.1
    UniProtKB/Swiss-Prot
    P15209
    Related
    ENSMUSP00000153553.2, ENSMUST00000225488.2
    Conserved Domains (5) summary
    cd05855
    Location:301379
    Ig_TrkB_d5; Fifth domain (immunoglobulin-like) of Trk receptor TrkB
    cd05093
    Location:531818
    PTKc_TrkB; Catalytic domain of the Protein Tyrosine Kinase, Tropomyosin Related Kinase B
    pfam13855
    Location:92150
    LRR_8; Leucine rich repeat
    pfam16920
    Location:152195
    TPKR_C2; Tyrosine-protein kinase receptor C2 Ig-like domain
    cl11960
    Location:205283
    Ig; Immunoglobulin domain
  3. NM_008745.3NP_032771.1  BDNF/NT-3 growth factors receptor isoform b precursor

    See identical proteins and their annotated locations for NP_032771.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks several exons and uses an alternate 3'-terminal exon, compared to variant 1. The encoded isoform (b) has a shorter and distinct C-terminus, compared to isoform a.
    Source sequence(s)
    AK018789, AK147441, AK160789, BP757570
    Consensus CDS
    CCDS36685.1
    UniProtKB/Swiss-Prot
    P15209
    UniProtKB/TrEMBL
    Q3UHE3
    Related
    ENSMUSP00000153270.2, ENSMUST00000224259.2
    Conserved Domains (6) summary
    cd05855
    Location:301379
    Ig_TrkB_d5; Fifth domain (immunoglobulin-like) of Trk receptor TrkB
    sd00031
    Location:96116
    LRR_1; leucine-rich repeat [structural motif]
    cl02423
    Location:3160
    LRRNT; Leucine rich repeat N-terminal domain
    pfam13855
    Location:92150
    LRR_8; Leucine rich repeat
    pfam16920
    Location:152195
    TPKR_C2; Tyrosine-protein kinase receptor C2 Ig-like domain
    cl11960
    Location:205283
    Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000079.7 Reference GRCm39 C57BL/6J

    Range
    58954286..59281784
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030247188.1XP_030103048.1  BDNF/NT-3 growth factors receptor isoform X2

    Conserved Domains (6) summary
    cd05855
    Location:301379
    Ig_TrkB_d5; Fifth domain (immunoglobulin-like) of Trk receptor TrkB
    sd00031
    Location:96116
    LRR_1; leucine-rich repeat [structural motif]
    pfam01462
    Location:3160
    LRRNT; Leucine rich repeat N-terminal domain
    pfam13855
    Location:92150
    LRR_8; Leucine rich repeat
    pfam16920
    Location:152195
    TPKR_C2; Tyrosine-protein kinase receptor C2 Ig-like domain
    cl11960
    Location:205283
    Ig; Immunoglobulin domain
  2. XM_036157911.1XP_036013804.1  BDNF/NT-3 growth factors receptor isoform X3

    Conserved Domains (7) summary
    sd00031
    Location:96116
    LRR_1; leucine-rich repeat [structural motif]
    pfam01462
    Location:3160
    LRRNT; Leucine rich repeat N-terminal domain
    pfam13855
    Location:92150
    LRR_8; Leucine rich repeat
    pfam16920
    Location:152195
    TPKR_C2; Tyrosine-protein kinase receptor C2 Ig-like domain
    cd00096
    Location:205209
    Ig; Ig strand A' [structural motif]
    cd05855
    Location:286379
    IgI_TrkB_d5; Fifth domain (immunoglobulin-like) of Trk receptor TrkB; member of the I-set of Ig superfamily (IgSF) domains
    cl11960
    Location:205283
    Ig; Immunoglobulin domain
  3. XM_006517149.5XP_006517212.1  BDNF/NT-3 growth factors receptor isoform X1

    See identical proteins and their annotated locations for XP_006517212.1

    UniProtKB/Swiss-Prot
    P15209
    Conserved Domains (5) summary
    cd05855
    Location:301379
    Ig_TrkB_d5; Fifth domain (immunoglobulin-like) of Trk receptor TrkB
    cd05093
    Location:531818
    PTKc_TrkB; Catalytic domain of the Protein Tyrosine Kinase, Tropomyosin Related Kinase B
    pfam13855
    Location:92150
    LRR_8; Leucine rich repeat
    pfam16920
    Location:152195
    TPKR_C2; Tyrosine-protein kinase receptor C2 Ig-like domain
    cl11960
    Location:205283
    Ig; Immunoglobulin domain
  4. XM_030247189.2XP_030103049.1  BDNF/NT-3 growth factors receptor isoform X4

    Conserved Domains (6) summary
    cd05855
    Location:301379
    Ig_TrkB_d5; Fifth domain (immunoglobulin-like) of Trk receptor TrkB
    sd00031
    Location:96116
    LRR_1; leucine-rich repeat [structural motif]
    cl02423
    Location:3160
    LRRNT; Leucine rich repeat N-terminal domain
    pfam13855
    Location:92150
    LRR_8; Leucine rich repeat
    pfam16920
    Location:152195
    TPKR_C2; Tyrosine-protein kinase receptor C2 Ig-like domain
    cl11960
    Location:205283
    Ig; Immunoglobulin domain
  5. XM_006517152.4XP_006517215.1  BDNF/NT-3 growth factors receptor isoform X4

    See identical proteins and their annotated locations for XP_006517215.1

    UniProtKB/Swiss-Prot
    P15209
    UniProtKB/TrEMBL
    Q3UHE3
    Conserved Domains (6) summary
    cd05855
    Location:301379
    Ig_TrkB_d5; Fifth domain (immunoglobulin-like) of Trk receptor TrkB
    sd00031
    Location:96116
    LRR_1; leucine-rich repeat [structural motif]
    cl02423
    Location:3160
    LRRNT; Leucine rich repeat N-terminal domain
    pfam13855
    Location:92150
    LRR_8; Leucine rich repeat
    pfam16920
    Location:152195
    TPKR_C2; Tyrosine-protein kinase receptor C2 Ig-like domain
    cl11960
    Location:205283
    Ig; Immunoglobulin domain
  6. XM_006517150.5XP_006517213.1  BDNF/NT-3 growth factors receptor isoform X2

    Conserved Domains (6) summary
    cd05855
    Location:301379
    Ig_TrkB_d5; Fifth domain (immunoglobulin-like) of Trk receptor TrkB
    sd00031
    Location:96116
    LRR_1; leucine-rich repeat [structural motif]
    pfam01462
    Location:3160
    LRRNT; Leucine rich repeat N-terminal domain
    pfam13855
    Location:92150
    LRR_8; Leucine rich repeat
    pfam16920
    Location:152195
    TPKR_C2; Tyrosine-protein kinase receptor C2 Ig-like domain
    cl11960
    Location:205283
    Ig; Immunoglobulin domain
  7. XM_006517151.5XP_006517214.1  BDNF/NT-3 growth factors receptor isoform X3

    UniProtKB/TrEMBL
    A0A286YDA3
    Related
    ENSMUSP00000153333.2, ENSMUST00000224402.2
    Conserved Domains (7) summary
    sd00031
    Location:96116
    LRR_1; leucine-rich repeat [structural motif]
    pfam01462
    Location:3160
    LRRNT; Leucine rich repeat N-terminal domain
    pfam13855
    Location:92150
    LRR_8; Leucine rich repeat
    pfam16920
    Location:152195
    TPKR_C2; Tyrosine-protein kinase receptor C2 Ig-like domain
    cd00096
    Location:205209
    Ig; Ig strand A' [structural motif]
    cd05855
    Location:286379
    IgI_TrkB_d5; Fifth domain (immunoglobulin-like) of Trk receptor TrkB; member of the I-set of Ig superfamily (IgSF) domains
    cl11960
    Location:205283
    Ig; Immunoglobulin domain
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